Effects of ethanol and arachidonic acid pathway inihibitors on the effectiveness of gastric mucosa cytoprotection

Folia Morphologica

Volumn 60, Issue 1, 2001, Pages 47-56

  Lutnicki, K ^a   Szpringer, E ^a   Czerny, K ^a   Ledwozyw, A ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Antioxidants; Arachidonic acid pathway inhibitors; Cytoprotection; Ethanol; Oxygen free radicals

Indexed keywords

3 AMINO 1 (3 TRIFLUOROMETHYLPHENYL) 2 PYRAZOLINE; ALCOHOL; ANTIOXIDANT; ARACHIDONIC ACID; BICARBONATE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; DOCEBENONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROPEROXIDE; LEUKOTRIENE; LIPOXYGENASE INHIBITOR; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; PIRMAGREL; PROSTAGLANDIN; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; THROMBOXANE; THROMBOXANE A2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; MUCUS SECRETION; NONHUMAN; PEROXIDASE ANTIPEROXIDASE COMPLEX; RAT; STOMACH MUCOSA; STOMACH MUCUS;

ANIMALS; ANTIOXIDANTS; ARACHIDONIC ACID; BENZOQUINONES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ENZYME INHIBITORS; ETHANOL; GASTRIC MUCOSA; IMIDAZOLES; LIPID PEROXIDATION; LIPOXYGENASE INHIBITORS; MALE; PYRIDINES; RATS; RATS, WISTAR; STOMACH ULCER; SUPEROXIDE DISMUTASE;

ANIMALIA;

EID: 0035101351     PISSN: 00155659     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Microsomal lipid peroxidation
2. Free fatty acids, oxygen free radicals, and membrane alterations in brain ischemia and injury
3. Ethanol and the antioxidant defence in the gastrointestinal tract
4. Measurement of catalase activity in tissue extracts
5. Ultrastructural changes of canine gastric mucosa after topical application of graded concentrations of ethanol
6. Oxygen radicals and other oxidants: Their generation, specificity and reactivity in biological systems
7. Adaptation of gastric mucosa to stress. Effect of ranitidine
8. Mechanism of gastrointestinal toxicity of NSAIDs
9. Oxidative stress and mitochondrial damage precedes gastric mucosal cell death induced by ethanol administration
10. Role of oxygen-derived free radicals in hemorrhagic shock-induced lesions in the rat
11. Second messenger role of arachidonic acid and its metabolites in interferon-gamma production
12. Reaktywne formy tlenu a regulacja ekspresji genów
13. Apoptosis in gastric mucosa with stress-induced gastric ulcers
14. Verapamil worsens ethanol-induced gastric ulcers in rats
15. Role of arachidonic acid metabolites in acute gastric lesions induced by indomethacin in rats
16. The relationship between plasma triglicerydes, cholesterol, total lipids peroxidation products during human atherosclerosis
17. Leukotrienes and other products of the 5-lipooxygenase pathway. Biochemistry and relation to pathology in human diseases
18. Antioxidants inhibit ethanol-induced gastric injury in the rat. Role of manganese, glycine, and carotene
19. Protein measurement with the Folin phenol reagent
20. Role of polymorphonuclear leucocytes and oxygen-derived free radicals in the formation of gastric lesions induced by HCI/ethanol, and a possible mechanism of protection by anti-ulcer polysaccharide
21. The role of superoxide anion in the autooxidation of epineprine and a simple assay for superoxide dismutase
22. Changes in superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activities and thiobaarbituric acid-reactive products levels in early stages in development in dystrophic chickens
23. Ethanol-induced gastrointestinal damage. Influence of endogenous antioxidant components and gender
24. Role of oxygen radicals in ethanol-induced damage to cultured gastric mucosal cells
25. Studies on the quantitative and qualitative characterisation of erythrocyte glutathione peroxidase
26. Pharmacology of mucus
27. Synthesis of lipooxygenase metabolites of arachidonic acid and their role in the pathogenesis of inflammation of gastric mucosa
28. Gastrointestinal Toxicity. Role of prostaglandins and leukotrienes
29. Ethanol stimulates formation of leukotriene C4 in rat gastric mucosa
30. Peroxydasen
31. A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats
32. Role of endogenous prostaglandins in preventing gastrointestinal ulceration: Induction of ulcers by antibodies to prostaglandins
33. Prostaglandins: Effects on gastrointestinal tract
34. Role of mucus in gastric mucosal protection
35. Apoptosis: Genetically programmed physiologic cell loss in normal gastric oxyntic mucosa and in mucosa of grossly healed gastric ulcer
36. Anti-ulcer effects of antioxidants, querticin, alpha-tocoferol, nifedipine and tetracycline in rats
37. Cellular and molecular mechanisms of gastric ulcer healing. Is the quality of mucosal scar affected by treatment?
38. Endogenous mediators of mucosal injury and protection
39. Mucosal defence. New Avenues for treatment of ulcer disease
40. Effects of leukotrienes on susceptibility of the rat stomach damage and investigations of the mechanism of action
41. Systemic complement activation lung injury and products of lipid peroxidation
42. Proulcerogenic eicosanoids and related lipid mediators in gastric mucosal damage