Oxidative stress and mitochondrial damage precedes gastric mucosal cell death induced by ethanol administration

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 3 SUPPL. 1, 1998, Pages

  Hirokawa, M ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Ethanol; Gastric mucosal cells; Glutathione; Mitochondrial permeability transition (mpt); Oxygen radicals

Indexed keywords

ALCOHOL; REACTIVE OXYGEN METABOLITE;

ANIMAL; ARTICLE; CELL DEATH; CELL LINE; DOSE RESPONSE; DRUG EFFECT; INTRACELLULAR MEMBRANE; LIPID PEROXIDATION; METABOLISM; MITOCHONDRION; RAT; STOMACH MUCOSA;

ANIMALS; CELL DEATH; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GASTRIC MUCOSA; INTRACELLULAR MEMBRANES; LIPID PEROXIDATION; MITOCHONDRIA; RATS; REACTIVE OXYGEN SPECIES;

EID: 0032063022     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/acer.1998.22.s3_part1.111s     Document Type: Article

References (3)

1. Feinman L, Korsten MA, Lieber CS: Alcohol and the digestive tract, in Lieber CS (ed): Medical and Nutritional Complication of Alcoholism. Mechanism and Management. 1992. New York, Plenum Publishing Co., 1992, p 307
2. Pihan G, Regillo C, Szabo S: Free radicals and lipid peroxidation in ethanol- or aspirin-induced gastric mucosal injury. Dig Dis Sci 32:1395-1401
3. Szelenyi I, Brune K: Possible role of oxygen free radicals in ethanol-induced gastric mucosal damage in rats. Dig Dis Sci 33:865-871, 1988