An alternative cis-isoprenyltransferase activity in yeast that produces polyisoprenols with chain lengths similar to mammalian dolichols

Glycobiology

Volumn 11, Issue 1, 2001, Pages 89-98

  Schenk, Barbara ^a   Rush, Jeffrey S ^b   Waechter, Charles J ^b   Aebi, Markus ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Cis isoprenyltransferase; Endoplasmic reticulum; Polyprenol biosynthesis; Protein N glycosylation

Indexed keywords

DOLICHOL; DOLICHOL PHOSPHATE; FARNESYL DIPHOSPHATE; ISOPRENALINE; ISOPRENE; ISOPRENOID; ISOPRENYLTRANSFERASE; LIPID; TRANSFERASE; UNCLASSIFIED DRUG;

ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; CATALYSIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ESCHERICHIA COLI; EUKARYOTIC CELL; FUNGUS GROWTH; GENE DELETION; GENE LOCUS; GENE OVEREXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAMMAL; MAMMAL CELL; MICROCOCCUS LUTEUS; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; REVERTANT; SACCHAROMYCES CEREVISIAE; YEAST; YEAST CELL;

ARABIDOPSIS; ARABIDOPSIS THALIANA; ESCHERICHIA COLI; EUKARYOTA; FUNGI; MAMMALIA; MICROCOCCUS LUTEUS; SACCHAROMYCES CEREVISIAE;

EID: 0035094506     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/11.1.89     Document Type: Article

References (57)

1. Characterization of the Saccharomyces cerevisiae cis-prenyltransferase required for dolichyl phosphate biosynthesis
2. Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: Cloning, expression and characterization of the essential uppS gene
3. Sec59 encodes a membrane protein required for core glycosylation in Saccharomyces cerevisiae
4. The dolichol pathway of N-linked glycosylation
5. Stepwise assembly of the lipid-linked oligosaccharide in the endoplasmic reticulum of Saccharomyces cerevisiae: Identification of the ALG9 gene encoding a putative mannosyl transferase
6. Enhancement of protein glycosylation in tissue slices by dolichylphosphate
7. Long-chain cis-isoprenyltransferase activity is induced early in the developmental program for protein N-glycosylation in embryonic rat brain cells
8. Characterization and localization of a long-chain isoprenyltransferase activity in porcine brain: Proposed role in the biosynthesis of dolichyl phosphate
9. Induction of dolichyl-saccharide intermediate biosynthesis corresponds to increased long chain cis-isoprenyltransferase activity during the mitogenic response in mouse B cells
10. Biosynthesis of dolichol phosphate by subcellular fractions from liver
11. Protein C-mannosylation is enzyme-catalysed and uses dolichyl-phosphate-mannose as a precursor
12. Conditions for quantitation of dolichyl phosphate, dolichol, ubiquinone and cholesterol by HPLC
13. Isoprenoid biosynthesis in rat liver peroxisomes. Characterization of cis-prenyltransferase and squalene synthetase
14. Yeast secretory mutants that block the formation of active cell surface enzymes
15. Genes required for completion of import of proteins into the endoplasmic reticulum in yeast
16. Allele-specific suppression of a Saccharomyces cerevisiae prp20 mutation by overexpression of a nuclear serine/threonine protein kinase
17. Studies on the biosynthesis of dolichyl phosphate: Evidence for the in vitro formation of 2, 3-dehydrodolichyl phosphate
18. Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins
19. A developmental change in dolichyl phosphate mannose synthase activity in pig brain
20. Effect of exogenous dolichyl monophosphate on a developmental change in mannosylphosphoryldolichol biosynthesis
21. Carbohydrate moeity of carboxypeptidase Y and perturbation of its biosynthesis
22. Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity
23. Topography of glycosylation in the rough endoplasmic reticulum and Golgi apparatus
24. Synthesis of the N-linked oligosaccharides of glycoproteins. Assembly of the lipid-linked precursor oligosaccharide and its relation to protein synthesis in vivo
25. The Escherichia coli homologue of yeast RER2, a key enzyme of dolichol synthesis, is essential for carrier lipid formation in bacterial cell wall synthesis
26. The oligosaccharyltransferase complex from yeast
27. Long-term effect of cyclic AMP on N-glycosylation is caused by an increase in the activity of the cis-prenyltransferase
28. Assembly of asparagine-linked oligosaccharides
29. The importance of being dolichol
30. Metabolism and function of polyisoprenol sugar intermediates in membrane-associated reactions
31. Increase in the lipid intermediate pathway of protein glycosylation during hen oviduct differentiation
32. Molecular cloning, expression and functional analysis of a cis-prenyltransferase from Arabidopsis thaliana
33. Alteration of the product specificities of prenyltransferases by metal ions
34. Specificity of solubilized yeast glycosyl transferases for polyprenyl derivatives
35. Identification of Schizosaccharomyces pombe prenol as dolichol-16, 17
36. Distribution, metabolism and function of dolichol and polyprenols
37. Regulation of glycosylation. Three enzymes compete for a common pool of dolichyl phosphate in vivo
38. Use of polymerase chain reaction for rapid detection of gene insertions in whole yeast cells
39. The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis
40. Molecular cloning, expression and purification of undecaprenyl diphosphate synthase. No sequence similarity between E- and Z-prenyl diphosphate synthases
41. Biochemistry, molecular biology and genetics of the oligosaccharyltransferase
42. Control of N-linked carbohydrate unit synthesis in thyroid endoplasmic reticulum by membrane organization and dolichyl phosphate availability
43. Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole
44. Protein O-mannosylation
45. Products of S. cerevisiae cis-prenyltransferase activity in vitro
46. Polyprenol formation in the yeast Saccharomyces cerevisiae: Effect of farnesyl diphosphate synthase overexpression
47. GPI-anchor biosynthesis
48. The yeast WBP1 is essential for oligosaccharyl transferase activity in vivo and in vitro
49. The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast
50. Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae
51. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
52. The site of biosynthesis and intracellular deposition of dolichol in rat liver
53. Oligosaccharyltransferase: A complex multisubunit enzyme of the endoplasmic reticulum
54. STT3, a highly conserved protein required for yeast oligosaccharyl transferase activity in vivo