Insulin-like growth factor 1 blocks collagen release and down regulates matrix metalloproteinase-1, -3, -8, and -13 mRNA expression in bovine nasal cartilage stimulated with oncostatin M in combination with interleukin 1α

Annals of the Rheumatic Diseases

Volumn 60, Issue 3, 2001, Pages 254-261

  Hui, W ^a   Rowan, A D ^a   Cawston, T ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGENASE; COLLAGENASE 3; HYDROXYPROLINE; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; NEUTROPHIL COLLAGENASE; ONCOSTATIN M; RECOMBINANT INTERLEUKIN 1ALPHA; RECOMBINANT SOMATOMEDIN C; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ARTICLE; CARTILAGE CELL; CHONDROLYSIS; COLLAGEN SYNTHESIS; COW; DOWN REGULATION; DRUG INHIBITION; ENZYME ACTIVITY; HUMAN; NONHUMAN; NORTHERN BLOTTING; NOSE CARTILAGE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; BLOTTING, NORTHERN; CARTILAGE; CATTLE; CELLS, CULTURED; CHONDROCYTES; COLLAGEN; DOWN-REGULATION; GENE EXPRESSION; HUMANS; HYDROXYPROLINE; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-1; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 8; ONCOSTATIN M; PEPTIDES; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 0035093381     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.60.3.254     Document Type: Article

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