Comparison of the systemic effects of fluticasone propionate and budesonide given by dry powder inhaler in healthy and asthmatic subjects

Thorax

Volumn 56, Issue 3, 2001, Pages 186-191

  Harrison, T W ^a   Wisniewski, A ^a   Honour, J ^b   Tattersfield, A E ^a  

^a NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

Asthma; Inhaled corticosteroids; Systemic effects

Indexed keywords

BUDESONIDE; DRUG METABOLITE; FLUTICASONE PROPIONATE; OSTEOCALCIN; PLACEBO;

ADOLESCENT; ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG URINE LEVEL; DRY POWDER; FEMALE; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LONG TERM CARE; MALE; OSTEOPOROSIS; PRIORITY JOURNAL;

ADMINISTRATION, INHALATION; ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; ANDROSTADIENES; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASTHMA; BUDESONIDE; DOUBLE-BLIND METHOD; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; POWDERS;

EID: 0035092070     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.56.3.186     Document Type: Article

References (25)

1. Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue to smoke
2. Use of inhaled corticosteroids and the risk of cataracts
3. High dose inhaled corticosteroids and dose dependent loss of diabetic control
4. Inhaled corticosteroid use and bone-mineral density in patients with asthma
5. Comparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients
6. Effects of budesonide and fluticasone on 24-hour plasma cortisol
7. Assessment of the relative systemic potency of inhaled fluticasone and budesonide
8. Adrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients
9. A dose-response study comparing suppression of plasma cortisol induced by fluticasone propionate from Diskhaler and budesonide from Turbuhaler
10. A comparison of fluticasone propionate, 1 mg daily, with beclomethasone dipropionate, 2 mg daily, in the treatment of severe asthma
11. High dose fluticasone propionate, 1 mg daily, versus fluticasone propionate, 2 mg daily, or budesonide 1.6 mg daily, in patients with chronic severe asthma
12. Comparison of fluticasone propionate with beclomethasone dipropionate in moderate to severe asthma treated for one year
13. Clinical experience with fluticasone propionate in asthma: A meta-analysis of efficacy and systemic activity compared with budesonide and beclomethasone dipropionate at half the microgram dose or less
14. Adrenal function in asthma
15. Rapid method for measurement of bronchial responsiveness
16. Randomised placebo controlled trial of β-agonist dose reduction in asthma
17. Pharmacokinetics and systemic effects of inhaled fluticasone propionate are different in asthmatic and normal volunteers
18. Nocturnal cortisol secretion in asthmatic patients after inhalation of fluticasone propionate
19. Efficacy and safety of inhaled corticosteroids in asthma
20. Inhaled corticosteroids: Benefits and risks
21. Dose-response comparison of systemic bioactivity with inhaled budesonide and triamcinolone acetonide in asthmatic adults
22. Differential effects of inhaled budesonide and oral prednisolone on serum osteocalcin
23. Effects of dose and dosing schedule of inhaled budesonide on bone turnover
24. Short-term dose-response relationship for the relative systemic effects of oral prednisolone and inhaled fluticasone in asthmatic adults
25. Molecular mechanisms of glucocorticoid action: What is important?