Profiling the immune response in patients with breast cancer by phage-displayed cDNA libraries

European Journal of Immunology

Volumn 31, Issue 3, 2001, Pages 716-725

  Sioud, Mouldy ^a   Hansen, Mona H ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Breast cancer; cDNA library; Immune response; Phage display; SEREX

Indexed keywords

CALMODULIN; CATHEPSIN L; COMPLEMENTARY DNA; GENE PRODUCT; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN G; INTEGRIN; INTERLEUKIN 2; INTERLEUKIN 6; MESSENGER RNA; PENTRAXIN; POLYCLONAL ANTIBODY; PROTEIN BCL X; PROTEIN P53; RECOMBINANT PROTEIN; RIBOSOME PROTEIN;

ANTIGEN BINDING; ANTIGEN DETECTION; ARTICLE; BACTERIOPHAGE M13; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; DNA LIBRARY; ESCHERICHIA COLI; GENE SEQUENCE; GENETIC CODE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; MOLECULAR CLONING; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

ANTIBODIES, NEOPLASM; ANTIGENS, NEOPLASM; BACTERIOPHAGE M13; BREAST NEOPLASMS; C-REACTIVE PROTEIN; ESCHERICHIA COLI; FEMALE; GENE LIBRARY; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN G; NERVE TISSUE PROTEINS; PEPTIDE LIBRARY; RNA, MESSENGER; SEQUENCE ANALYSIS, PROTEIN; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035080338     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200103)31:3<716::AID-IMMU716>3.0.CO;2-9     Document Type: Article

References (46)

1. Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
2. Searching for peptide ligands with an epitope library
3. Probing the basis of antibody reactivity with a panel of constrained peptide libraries displayed by filamentous phage
4. Human anti-self antibodies with high specificity from phage display libraries
5. Identification of new B cell epitopes in the sera of rheumatoid arthritis patients using a random nanopeptide phage library
6. Characterization of naturally occurring autoantibodies against tumour necrosis factor-alpha (TNF-α):. In vitro function and precise epitope mapping by phage epitope library
7. Peptide phage libraries can be an efficient tool for identifying antibody ligands for polyclonal antisera
8. A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera
9. Identification of polyclonal serum specificities with phage-display libraries
10. Selection of ligands for polyclonal antibodies from random peptide libraries: Potential identification of (auto)antigens that may trigger B and T cell responses in autoimmune diseases
11. Selection of biologically active peptides using random libraries displayed on phage
12. T-cell-mediated cytotoxicity against autologous malignant melanoma: Analysis with interleukin 2-dependent T cell cultures
13. Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes
14. Serological analysis of human tumor antigens: Molecular definition and implications
15. New paths in human cancer serology
16. Cancer antigens: Immune recognition of self and altered self
17. Clonal analysis and in situ characterization of lymphocytes infiltrating human breast carcinomas
18. Limited heterogeneity in the T-cell receptor V-gene usage in lymphocytes infiltrating human colorectal tumours
19. Immunologic nonresponsiveness to tumors
20. Human neoplasms elicit multiple specific immune responses in the autologous host
21. Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library
22. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
23. A survey of the humoral immune response of cancer patients to a panel of human tumor antigens
24. Derivation of vaccines from mimotopes: Immunogenic properties of human hepatitis b virus surface antigen mimotopes displayed on filamentous phage
25. Increased serum and synovial fluid antibodies to immunoselected peptides in patients with rheumatoid arthritis
26. Surface expression and ligand-based selection of cDNAs fused to filamentous phage gene VI
27. Display of expression products of cDNA libraries on phage surfaces
28. Expression cloning of cDNA by phage display selection
29. Cloning of ligand binding domains of bacterial receptors by phage display
30. Phage display shot-gun cloning of ligand-binding domains of prokaryotic receptors approaches 100% correct clones
31. Efficient display of an HCV cDNA expression library as C-terminal fusion to the capsid protein D of bacteriophage lambda
32. The relationship between serum p53 autoantibodies and characteristics of human breast cancer
33. High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F Clin
34. Immunogenicity and epitope mapping of foreign sequences via genetically engineered filamentous phage
35. The fibroblast growth factor family
36. The translation initiation factor elF3-p48 subunit is encoded by int-6, a site of frequent integration by the mouse mammary tumor virus genome
37. Translation initiation factor elF-4γ is encoded by an amplified gene and includes an immune response in squamous cell lung carcinoma
38. Int-2 oncogene amplification and prognosis in node-negative breast carcinoma
39. Human lung cancer antigens recognized by autologous antibodies: Definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3
40. Cathepsin L2, a novel human cysteine proteinase produced by breast and colorectal carcinomas
41. The p150-spir protein provides a link between c-Jun N-terminal kinase function and actin reorganization
42. Ribosomal protein genes are overexpressed in colorectal cancer: Isolation of a cDNA clone encoding the human S3 ribosomal protein
43. Several genes encoding ribosomal proteins are over-expressed in protaste-cancer cell lines
44. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells
45. Mouse and human neuronal pentraxin (NPTX1): Conservation, genomic structure, and chromosomal localization