Early markers of brain damage in premature low-birth-weight neonates who suffered from perinatal asphyxia and/or infection

Biology of the Neonate

Volumn 79, Issue 3-4, 2001, Pages 213-218

  Fotopoulos, S ^a   Pavlou, K ^a   Skouteli, H ^a   Papassotiriou, I ^a   Lipsou, N ^a   Xanthou, M ^a  

^a AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

Author keywords

Interleukin 1 ; Interleukin 6; Low birth weight; Nucleated red blood cells; Periventricular leucomalacia; Tumour necrosis factor

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

APGAR SCORE; BRAIN INJURY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; ERYTHROCYTE COUNT; HUMAN; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; NEUROLOGIC EXAMINATION; NEUROLOGICAL COMPLICATION; NEWBORN; PERINATAL ASPHYXIA; PERINATAL INFECTION; PREMATURITY; PRIORITY JOURNAL;

ASPHYXIA NEONATORUM; BIOLOGICAL MARKERS; BRAIN DISEASES; CELL COUNT; ERYTHROCYTES; GESTATIONAL AGE; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; INFECTION; INTERLEUKIN-1; INTERLEUKIN-6; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035079138     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000047094     Document Type: Conference Paper

References (54)

1. Escobar GJ, Littenberg B, Petitt DB: Outcome among surviving very low birthweight infants: A meta-analysis. Arch Dis Child 1991;66:204-211.
2. Murphy DJ, Seller S, MacKenzie IZ, Yudkin PL, Johnson AM: Case-control study of antenatal and intrapartum risk factors for cerebral palsy in very preterm single babies. Lancet 1995;346:1449-1454.
3. Hack M, Friedman H, Fanaroff A: Outcome of extremely low birth weight infants. Pediatrics 1996;98:931-937.
4. Perlman J: White matter injury in the preterm infant: An important determination of abnormal neurodevelopment outcome. Early Hum Dev 1998;53:99-120.
5. Vannucci RC: Current and potentially new management strategies for perinatal hypoxic-ischemic encephalopathy. Pediatrics 1990;85:961-968.
6. Goldberg RN, Morosco P, Bauer CR, Bloom FL, Curless RG, Burke B, Bancalari E: Use of barbiturate therapy in severe perinatal asphyxia: A randomized controlled trial. J Pediatr 1986;109:851-856.
7. Martin-Ancel A, Garcia-Alix A, Pascual-Salcedo D, Cabanas F, Valcarce M, Quero J: Interleukin-6 in the cerebrospinal fluid after perinatal asphyxia is related to early and late neurological manifestations. Pediatrics 1997;100:789-794.
8. Leviton A, Paneth N, Reuss ML, Susser M, Allred EN, Dammann O, Kuban K, Van Marter LJ, Pagano M: Maternal intrauterine infection, fetal inflammatory response and brain damage in very low birth weight infants. Pediatr Res 1999;46:566-575.
9. Dammann O, Leviton A: Maternal intrauterine infection, cytokines, and brain damage in the preterm newborn. Pediatr Res 1997;42:1-8.
10. Grether JK, Nelson KB, Emery ES III, Cummins SK: Prenatal and perinatal factors and cerebral palsy in very low birth weight infants. J Pediatr 1996; 128:407-414.
11. Murphy DJ, Hope PL, Johnson A: Neonatal risk factors for cerebral palsy in very preterm babies: Case-control study. BMJ 1997;314:404-408.
12. Yoon BH, Jun JK, Romero R, Park KH, Gomez R, Choi JH, Kim IO: Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy. Am J Obstet Gynecol 1997;177:19-26.
13. Yoon BH, Romero R, Yang SH, Jun JK, Kim IO, Choi JH, Syn HC: Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia. Am J Obstet Gynecol 1996; 174:1433-1440.
14. Naeye RL, Localio AR: Determining the time before birth when ischemia and hypoxemia initiated cerebral palsy. Obstet Gynecol 1995;86:713-719.
15. Green DW, Hendon B, Mimouni FB: Nucleated erythrocytes and intraventricular hemorrhage in preterm neonates. Pediatrics 1995;96:475-478.
16. Leikin E, Verma U, Klein S, Tejani N: Relationship between neonatal nucleated red blood cell counts and hypoxic-ischemic injury. Obstet Gynecol 1996;87:439-443.
17. Korst LM, Phelan JP, Ahn MO, Martin GI: Nucleated red blood cells: An update on the marker for fetal asphyxia. Am J Obstet Gynecol 1996;175: 843-846.
18. Buonocore G, Perrone S, Gioia D, Gatti MG, Massafra C, Agosta R, Bracci R: Nucleated red blood cell counts at birth as an index of perinatal brain damage. Am J Obstet Gynecol 1999;181:1500-1505.
19. Perlman JM: Markers of asphyxia and neonatal brain damage. N Engl J Med 1999;341:364-365.
20. Badawi N, Kurinczuk JJ, Keogh JM, Alessandri LM, O'Sullivan F, Burton PR, Pemberton PJ, Stanley FJ: Intrapartum risk factors for newborn encephalopathy: The Western Australian case-control study. BMJ 1998;317:1554-1558.
21. Savman K, Blennow M, Gustafson K, Tarkowski E, Hagberg H: Cytokine response in cerebrospinal fluid after birth asphyxia. Pediatr Res 1998;43: 746-751.
22. Singh B, Merchant P, Walker CR, Kryworuchko M, Mitoma FD: Interleukin-6 expression in cord blood of patients with clinical chorioamnionitis. Pediatr Res 1996;39:976-979.
23. Berner R, Niemeyer CM, Leititis JU, Funke A, Schwab C, Rau U, Richter K, Tawfeek MSK, Clad A, Brandis M: Plasma levels and gene expression of granulocyte colony-stimulating factor, tumor necrosis factor-α, interleukin (IL)-1β, IL-6, IL-8 and soluble intercellular adhesion molecule-1 in neonatal early onset sepsis. Pediatr Res 1998;44:469-477.
24. Paterakis G, Lykopoulou L, Papassotiriou I, Stamouylakatou A, Loukopoulos D: Direct estimation of nucleated red cell counts in thalassemia and sickle cell disease by the R-1000 (SYSMEX) apparatus (abstract). Blood 1994;84:557.
25. Amiell-Tison C: Neuromotor status; in Taeusch HW, Yogman MW (eds): Follow-Up Management of the High-Risk Infant. Boston, Little, Brown, 1987, pp 115-126.
26. Nelson KB, Dambrosia JM, Grether JK, Phillips TM: Neonatal cytokines and coagulation factors in children with cerebral palsy. Ann Neurol 1998;44: 665-675.
27. Miller LC, Isa S, Lopreste G, Schaller JG, Dinarello CA: Neonatal interleukin-1β, interleukin-6 and tumor necrosis factor: Cord blood levels and cellular production. J Pediatr 1990;117:961-965.
28. O'Shea TM, Klinepeter KL, Meis PJ, Dillard RG: Intrauterine infection and the risk of cerebral palsy in very low-birthweight infants. Paediatr Perinat Epidemiol 1998;12:72-83.
29. Spinillo A, Capuzzo E, Orcesi S, Stronati M, Di Mario M, Fazzi E: Antenatal and delivery risk factors simultaneously associated with neonatal death and cerebral palsy in preterm infants. Early Hum Dev 1997;48:81-91.
30. Yoon BH, Romero R, Kim CJ, Jun JK, Gomez R, Choi JH, Syn HC: Amniotic fluid interleukin-6: A sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity. Am J Obstet Gynecol 1995;172:960-970.
31. Weeks JW, Reynolds L, Taylor D, Lewis J, Wan T, Gall SA: Umbilical cord blood interleukin-6 levels and neonatal morbidity. Obstet Gynecol 1997;90: 815-818.
32. Palmer C: Hypoxic-ischemic encephalopathy. Therapeutic approaches against microvascular injury and role of neutrophils, PAF and free radicals. Clin Perinatol 1995;22:481-517.
33. Fellman V, Raivio KO: Reperfusion injury as the mechanism of brain damage after perinatal asphyxia. Pediatr Res 1997;41:599-606.
34. Ghezzi P, Dinarello CA, Bianchi M, Rosandrich ME, Repine JE, White CW: Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells. Cytokine 1991;3: 189-194.
35. Garcia JH, Liu KF, Yoshida Y, Lian J, Chen S, Zoppo GJ: Influx of leukocytes and platelets in an evolving brain infarct. Am J Pathol 1994;144:188-199.
36. McRae A, Gilland E, Bona E, Hadberg H: Microglia activation after neonatal hypoxic-ischemia. Dev Brain Res 1994;84:245-252.
37. Szaflarski J, Burtrum D, Silverstein FS: Cerebral hypoxia-ischemia stimulates cytokine gene expression in perinatal rats. Stroke 1995;26:1-8.
38. Hagberg H, Gilland E, Bona E, Hansson LA, Hahn-Zoric M, Hoist M, McRae A, Soder O: Enhanced expression of interleukin (IL)-1 and IL-6 messenger RNA and bioactive protein after hypoxia-ischemia in neonatal rats. Pediatr Res 1996;40: 603-609.
39. Adinolfi M: The development of the human blood-CSF-brain barrier. Dev Med Child Neurol 1985; 27:532-537.
40. Megyeri P, Abraham CS, Temesvari P, Kovacs J, Vas T, Speer CP: Recombinant human tumor necrosis factor alpha constricts pial arterioles and increases blood-brain barrier permeability in newborn piglets. Neurosci Lett 1992;148:137-140.
41. Seo K, McGregor JA, French JI: Preterm birth is associated with increased risk of maternal and neonatal infection. Obstet Gynecol 1992;79:75-80.
42. Perlman JM: Markers of asphyxia and neonatal brain injury. N Engl J Med 1999;341:364-365.
43. Leviton A: Preterm birth and cerebral palsy: Is tumor necrosis factor the missing link. Dev Med Child Neurol 1993;35:553-558.
44. Lee SC, Dickson DW, Lin W, Brosnan CF: Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ. J Neuroimmunol 1993;46:19-24.
45. Hattori H, Wasterlain CG: Excitatory amino acids in the developing brain, ontogeny, plasticity and excitotoxicity. Pediatr Neurol 1990;6:219-228.
46. Dammann O, Leviton A: Brain damage in preterm newborns: Might enhancement of developmentally regulated endogenous protection open a door for prevention. Pediatrics 1999;104:541-550.
47. Silverstein FS, Barks JDE, Hagan P, Liu XH, Ivacko J, Szaflarski J: Cytokines and perinatal brain injury. Neurochem Int 1997;30:375-383.
48. Volpe JJ: Neurology of the Newborn, ed 3. Philadelphia, Saunders, 1994, pp 876-884.
49. Perlman JM, Risser R: Can asphyxiated infants at risk for neonatal seizures be rapidly identified by current high-risk markers? Pediatrics 1996;97: 456-462.
50. Gilles FH, Leviton A, Kerr CS: Endotoxin leucoencephalopathy in the telencephalon of the newborn kitten. J Neurol Sci 1976;27:183-191.
51. Yoon BH, Romero R, Kim CJ, Koo JN, Choe G, Syn HC, Chi JG: High expression of tumor necrosis factor-alpha and interleukin-6 in periventricular leukomalacia. Am J Obstet Gynecol 1997;177: 406-411.
52. Hope PL, Gould SJ, Howard S, Hamilton PA, Costello AM, Reynolds EOR: Precision of ultrasound diagnosis of pathologically verified lesions in the brains of very preterm infants. Dev Med Child Neurol 1988;30:457-471.
53. Battin M, Maalouf EF, Counsell S, Herithy AH, Edwards AS: Magnetic resonance imaging of the brain of premature infants. Lancet 1997;349: 1741.
54. Dammann O, Leviton A: Brain damage in preterm newborns: Biological response modification as a strategy to reduce disabilities. J Pediatr 2000;136: 433-438.