Effects of lubeluzole on the methamphetamine-induced increase in extracellular glutamate and the long-term depletion of striatal dopamine

Synapse

Volumn 40, Issue 2, 2001, Pages 95-101

  Cohen Jr , M Michael ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Hyperthermia; In vivo microdialysis; Rat; Striatum; Veratridine

Indexed keywords

DOPAMINE; GLUTAMIC ACID; LUBELUZOLE; METHAMPHETAMINE; VERATRIDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; CONTROLLED STUDY; CORPUS STRIATUM; MALE; MICRODIALYSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN;

ANIMALS; BODY TEMPERATURE; DOPAMINE; DRUG INTERACTIONS; EXTRACELLULAR SPACE; GLUTAMIC ACID; MALE; METHAMPHETAMINE; NEOSTRIATUM; NEURONS; NEUROPROTECTIVE AGENTS; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS; THIAZOLES; VERATRIDINE;

EID: 0035077411     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.1030     Document Type: Article

References (46)

1. Effects of repeated administration of a high dose of methamphetamine on dopamine and glutamate release in rat striatum and nucleus accumbens
2. Low environmental temperatures or pharmacologic agents that produce hypothermia decrease methamphetamine neurotoxicity in mice
3. Methamphetamine and dopamine neurotoxicity: Differential effects of agents interfering with glutamatergic neurotransmission
4. The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum
5. Further studies of the role of hyperthermia in methamphetamine neurotoxicity
6. Methamphetamine selectively damages dopaminergic innervation to the nucleus accumbens core while sparing the shell
7. Free radicals and the pathobiology of brain dopamine systems
8. a-Phenyl-N-t-butyl nitrone attenuates methamphetamine-induced depletion of striatal dopamine without altering hyperthermia
9. Glutamate neurotoxicity and diseases of the nervous system
10. Oxidative stress, glutamate, and neurodegenerative disorders
11. Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress
12. Lubeluzole reduces mortality and improves functional outcome in the treatment of acute ischemic stroke: Early preclinical and clinical findings
13. Lubeluzole protects sensorimotor function and reduces infarct size in a photochemical stroke model in rats
14. Methamphetamine induced neuronal damage: A possible role for free radicals
15. An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates
16. Chemical release of dopamine from striatal homogenates: Evidence for an exchange diffusion model
17. Protection with lubeluzole against delayed ischemic brain damage in rats: A quantitative histopathologic study
18. Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain
19. Glutamatergic control of dopamine release in the rat striatum: Evidence for presynaptic N-methyl-D-aspartate receptors on dopaminergic nerve terminals
20. Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway
21. Comparison of the release of [3H]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine
22. Dopamine uptake inhibitors block long-term neurotoxic effects of methamphetamine upon dopaminergic neurons
23. Influence of lubeluzole on voltage-sensitive Ca++ channels in isolated rat neurons
24. Short-term and long-term effects of methamphetamine on biogenic amine metabolism in extrastriatal dopaminergic nuclei
25. Methamphetamine neurotoxicity and striatal glutamate release: Comparison to 3, 4-methylenedioxymethamphetamine
26. Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse
27. Multiple methamphetamine injections induce marked increases in extracellular striatal dopamine which correlates with subsequent neurotoxicity
28. The effects of the novel neuroprotective compound lubeluzole on sodium current and veratridine induced sodium load in rat brain neurons and synaptosomes
29. Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage
30. Developmental dissociation of methamphetamine-induced depletion of dopaminergic terminals and astrocyte reaction in rat striatum
31. The effects of amfonelic acid, a dopamine uptake inhibitor on methamphetamine-induced dopaminergic terminal degeneration and astrocytic response in rat striatum
32. Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: A regional study
33. Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain
34. Further evidence that amphetamines produce long-lasting dopamine neurochemical deficits by destroying dopamine nerve fibers
35. Extracellular changes of glutamate in the periinfarct zone. Effects of lubeluzole
36. Lubeluzole blocks increases in extra-cellular glutamate and taurine in the peri-infarct zone in rats
37. Role of dopamine uptake carrier in the neurochemical response to methamphetamine and effects of amfonelic acid
38. Long-term methamphetamine induced changes in brain catecholamines in tolerant rhesus monkeys
39. Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity
40. Competitive and non-competitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice
41. Methamphetamine-induced neurotoxicity: Roles for glutamate and dopamine efflux
42. Methamphetamine pretreatment and the vulnerability of the striatum to methamphetamine neurotoxicity
43. Substrates of energy metabolism attenuate methamphetamine-induced neurotoxicity in striatum
44. Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?
45. Methamphetamine induced changes in brain catecholamines in rats and guinea pigs
46. Amphetamine neurotoxicity: Roles for dopamine, glutamate and oxidative stress