Tri-dimensional prostate cell cultures in simulated microgravity and induced changes in lipid second messengers and signal transduction

Journal of Cellular and Molecular Medicine

Volumn 5, Issue 1, 2001, Pages 60-73

  Clejan, Sanda ^a,d   O'Connor, Kim ^b   Rosensweig, Nitsa ^c  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Tulane University   (United States)

^c XAVIER UNIVERSITY OF LOUISIANA   (United States)

^d TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CHOLINE; DIACYLGLYCEROL; INOSITOL PHOSPHATE; PHOSPHOLIPID;

ARTICLE; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; METABOLISM; METHODOLOGY; PROSTATE; SECOND MESSENGER; THIN LAYER CHROMATOGRAPHY; TIME; WEIGHTLESSNESS;

CELL CULTURE TECHNIQUES; CERAMIDES; CHOLINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; DIGLYCERIDES; HUMANS; INOSITOL PHOSPHATES; MALE; PHOSPHOLIPIDS; PROSTATE; SECOND MESSENGER SYSTEMS; TIME FACTORS; TUMOR CELLS, CULTURED; WEIGHTLESSNESS SIMULATION;

EID: 0035066676     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2001.tb00138.x     Document Type: Article

References (32)

1. O'Connor K.C., Three-dimensional cultures of prostatic cells: tissue models for the development of novel anti-cancer therapies, Pharm. Res., 16: 486493, 1999
2. Clejan S., O'Connor K.C., Cowger N.L., Cheles M.K., Haque S., Primavera A.C., Effects of simulated microgravity on DU-145 human prostate carcinoma cells, Biotech. Bioeng., 50: 587-597, 1996
3. O'Connor K.C., Enmon R., Primavera A., Dotson R. Clejan S., Characterization of extracellular matrix in three-dimensional cultures of DU-145 human prostate carcinoma cells. In: MJT Carrondo, JB Griffiths, C MacDonald, eds., Animal Cell Technology, Vaccines to Genetic Medicine, Kluwer Academic Publishers, Dordrecht, 1996, pp. 571-575
4. O'Connor K.C., Enmon R.M., Dotson R.S., Primavera A.C., Clejan S., Characterization of autocrine growth factors, their receptors and extracellular matrix present in three-dimensional cultures of DU-145 human prostate carcinoma cells grown in simulated microgravity, Tissue Eng., 3: 2,161171, 1997
5. Clejan S., Dotson R.S., Ide CF., Beckman B.S., Coordinated effects of electromagnetic field exposure on erythropoietin-induced activities of phosphadylinositol-phospholipase C and phosphatidylinositol 3kinase, Cell. Biochem. Biophys., 27: 203-225, 1997
6. Burrow M.E., Weldon C.B., Collins-Burrow B.M., Ramsey N., McKee A., Klippel A., McLachlan J.A., Clejan S., Beckman B.S., Cross-talk between phosphatidylinositol 3 -kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions., J. Biol. Chem., 275: 13;9628-9635, 2000
7. Clejan S., Analytical methods and steps to sample preparation for determination of molecular species of fatty acids. In: Bird I.M. and Clejan S, eds., Molecular Biology, Phospholipid Signaling Protocols, Humana Press, vol. 105, New Jersey, 1998, pp. 243-254
8. Burow M.E., Weldon C.B., Tang Y., Navar GL., Krajewski S., Reed J.C., Hammond T.G, Clejan S., Beckman B.S., Differences in susceptibility to tumor necrosis factor a-induced apoptosis among MCF-7 breast cancer cell variants, Cancer Res., 58: 1, 4940-4946, 1998
9. Garzotto M., White-Jones M., Jiang Y., Ehleiter D., Liao W.C., Haimovitz-Friedman A., Fuks Z., and Kolesnick R., 12-O-tetradecanoylphorbol-13-acetateinduced apoptosis in LNCaP cells is mediated through ceramide synthase, Cancer Res., 58: 2260-2264, 1998
10. Clejan S., Ide C., Walker C., Wolf E., Corb M., and Beckman B., Electromagnetic field induced changes in lipid second messengers, J. Lipid Med. Cell. Sig., 13: 301-324, 1996
11. Clejan S., Mallia C., Vinson D., Dotson, R, and Beckman B.S., Erythropoietin stimulates G-proteincoupled phospholipase D in haematopoietic target cells, Biochem. J., 314: 853-860, 1996
12. Clejan S., HPLC analytical methods for the separation of molecular species of fatty acids in diacylglycerol and cellular phospholipids. In: Bird I.M. and Clejan S, eds, Methods in Molecular Biology, Phospholipid Signaling Protocols, Vol. 105, Humana Press, New Jersey, 1998, pp. 255-274
13. Clejan S., Analysis of molecular species of cellular sphingomyelins and ceramides. In: Bird I.M. and Clejan S, eds, Methods in Molecular Biology, Phospholipid Signaling Protocols, Vol. 105, Humana Press, New Jersey, 1998, pp. 275-285
14. Beckman B.S., Mallia C., Clejan S., Molecular species of phospholipids in a murine stem cell line responsive to erythropoietin, Biochem. J., 314: Sol867, 1996
15. Susa M., Keeler M., Varticovski L., Platelet -derived growth factor activates membrane-associated phosphatidylinositol 3-kinase and mediates its translocation from the cytosol, J. Biol. Chem., 267: 22, 951956, 1992
16. Clejan S., Wolf E., Corb M., Dotson R., Ide C., Morphological differentiation of N1E-115 neuroblastorna cells by dimethyl sulfoxide and activation oflipid second messengers, Exp. Cell. Res., 224: 16-27, 1996
17. Coffer PJ., Jin J., Woodgett J.R., Protein kinase B (cAkt): a multifunctional mediator of phosphatidylinositol 3-kinase activation, Biochem. J., 335: 1-13, 1998
18. Downward J., Mechanisms and consequences of activation of protein kinase B/Akt, Curr. Opln. Cell. Biol, 10: 262-267, 1998
19. Kulik G, Weber M.J., Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor l, Mol. Cell. Biol., 18: 6711-6718, 1998
20. Dudek H., Datta S.R., Franke T.F., Birnbaum M.J., Yao R., Cooper GM., Segal R.A., Kaplan D.R., Greenberg M.E., Regulation of neuronal survival by the serine-threonine protein kinase Akt, Science, 275: 661-665, 1997
21. Chen R.-H., Su Y.-H., Chuang R.L.C., Chang T.Y., Suppression of transforming growth factor-betainduced apoptosis through a phosphatidylinositol 3kinase/Akt-dependent pathway, Oncogene, 17: 15,1959-1968, 1998
22. Eves E.M., Xiong W., Bellacosa A., Kennedy S.G, Tsichlis P.N., Rosner M.R., Hay N., Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line, Mol. Cell. BioL, 18: 4,2143-3252, 1998
23. Cuvillier O., Rosenthal D. S., Smulson M. E., Spiegel S., Sphingosine l-phosphate inhibits activation of caspases that cleave poly (ADP-ribose) polymerase and lamins during Fas- and ceramide- mediated apoptosis in Jurkat T lymphocytes, J. Biol. Chem., 273: 5,2910-2916, 1998
24. Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., Greenberg M.E., Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery, Cell, 91: 2,231-241, 1997
25. Scheid M.P., and Duronio V., Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation, Proc. Nail. Acad. Sci. USA, 95: 13,7439-7444, 1998
26. Zundel W., Giaccia A., Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress, Genes Dev, 12: 13,1941-1946, 1998
27. Summers S.A., Gar/a L.A., Zhou H., Birnbaum M.J., Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide, Mol. Cell. Biol, 18: 9,5457-5464, 1998
28. Zhou H., Summers S.A., Birnbaum M.J., Pirtman R.N., Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis, J. Biol. Chem., 273: 26,16568-16575, 1998
29. Dufourny B., Alblas J., van Teeffelen H.A., van Schaik F.M., van der Burg B., Steenbergh P.H., Sussenbach J.S., Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase, J. Biol. Chem., 272:49,31163-31171
30. Dethlefsen S.M., Shepro D., D'Amore P.A., Arachidonic acid metabolites in bFGF-, PDGF-, and serum-stimulated vascular cell growth, Exp. Cell. Res., 212: 262-273, 1994
31. Bang Y-J., Pirnia F., Fang W-G, Kang W.K., Sartor O., Whitesell L, Ha M.J., Tsokos M., Sheahan M.D., Nguyen R, Niklinski W.T., Myers C.E., Trepel J.B., Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP, Proc. Nail. Acad. Sci. USA, 91: 5330-5334, 1994
32. 2+ transients. Endocrinol., 134: 2, 596-602, 1994