Cross-regulation of Hox genes in the Drosophila melanogaster embryo

Mechanisms of Development

Volumn 102, Issue 1-2, 2001, Pages 3-16

  Miller, David F B ^a   Rogers, Bryan T ^a   Kalkbrenner, Amy ^a   Hamilton, Barbara ^a   Holtzman, Stacy L ^a   Kaufman, Thomas ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Central nervous system; Co linearity; Drosophila melanogaster; Ectoderm; Endoderm; Homeotic Complex; Hox; Phenotypic suppression; Posterior dominance; Posterior prevalence; Segmental register shift; Signal transduction; Visceral mesoderm

Indexed keywords

HOMEODOMAIN PROTEIN; PROTEIN;

ANIMAL TISSUE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; EPIDERMIS; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; HOMEOBOX; MESODERM; MUTANT; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; TIME; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

ANIMALS; ARABIDOPSIS PROTEINS; CENTRAL NERVOUS SYSTEM; CROSSES, GENETIC; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; GENOTYPE; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; INSECT PROTEINS; MESODERM; MICROSCOPY, CONFOCAL; MUTATION; NUCLEAR PROTEINS; PLANT PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0035064525     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00301-X     Document Type: Article

References (74)

1. Homeodomain proteins and the regulation of gene expression
2. The molecular basis for metameric pattern in the Drosophila embryo
3. Setting limits on homeotic gene function: Restraint of Sex combs reduced activity by teashirt and other homeotic genes
4. Homeotic transformation of legs to mouthparts by proboscipedia expression in Drosophila imaginal discs
5. Cell-type-specific mechanisms of transcriptional repression by the homeotic gene products Ubx and Abd-A in Drosophila embryos
6. Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes
7. An Ultrabithorax protein binds sequences near its own and the Antennapedia P1 promoters
8. Homeotic genes and positional signalling in the Drosophila viscera
9. Induction of the endoderm in Drosophila
10. TCF: Transcriptional activator or repressor?
11. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
12. Functional dominance among Hox genes: Repression dominates activation in the regulation of Dpp
13. Dissecting the temporal requirements for homeotic gene function
14. Temporal and spatial distribution of transcripts from the Deformed gene of Drosophila
15. Control of expression of the homeotic labial (lab) locus of Drosophila melanogaster: Evidence for both positive and negative autogenous regulation
16. Structural complexity and evolutionary conservation of the Drosophila homeotic gene proboscipedia
17. Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development
18. Developmental and evolutionary implications of labial, Deformed and engrailed expression in the Drosophila head
19. Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos
20. Colinearity and functional hierarchy among genes of the homeotic complexes
21. Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins
22. The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain
23. Control of Drosophila adult pattern by extradenticle
24. The developmental effect of over expressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products
25. Organization of the Drosophila head as revealed by the ectopic expression of the Ultrabithorax product
26. Autocatalysis and phenotypic expression of Drosophila homeotic gene Deformed its dependence on polarity and homeotic gene function
27. Genetic analysis of embryonic cis-acting regulatory elements of the Drosophila homeotic gene Sex combs reduced
28. Positive cross-regulation and enhancer sharing: Two mechanisms for specifying overlapping Hox expression patterns
29. 'Homeotic genes autonomously specific one aspect of pattern in the Drosophila mesoderm.'
30. Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila
31. Spatially regulated expression of homeotic genes in Drosophila
32. Homeotic genes have specific functional roles in the establishment of the Drosophila embryonic peripheral nervous system
33. The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis
34. Cross regulation of decapentaplegic and Ultrabithorax transcription in the embryonic visceral mesoderm of Drosophila
35. Pair-rule segmentation genes regulate the expression of the homeotic selector gene, Deformed
36. Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity
37. A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila
38. A functional analysis of 5′, intronic and promoter regions of the homeotic gene proboscipedia in Drosophila melanogaster
39. Molecular and genetic organization of the Antennapedia gene complex of Drosophila melanogaster
40. spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo
41. Ectopic expression of Ubx and Abd-B proteins during Drosophila embryogenesis: Competition, not a functional hierarchy, explains phenotypic suppression
42. A gene complex controlling segmentation in Drosophila
43. Functional hierarchy and phenotypic suppression among Drosophila homeotic genes: The labial and empty spiracles genes
44. Cross-regulation in the mouse HoxB complex: The expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1
45. Distribution of the Sex combs reduced gene products in Drosophila melanogaster
46. Novel patterns of homeotic protein accumulation in the head of the Drosophila embryo
47. The spatial and temporal deployment of Dfd and Scr transcripts throughout development of Drosophila
48. genetic and developmental analysis of mutations in the Deformed locus in Drosophila melanogaster
49. Homeotic Complex gene regulation and homeosis in the mesoderm of the Drosophila melanogaster embryo: The roles of signal transduction and cell autonomous regulation
50. Control of Drosophila head segment identity by the bZIP homeotic gene cnc
51. Alternative RNA products from the Ultrabithorax domain of the bithorax complex
52. A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis
53. The proboscipedia locus of the Antennapedia complex: A molecular and genetic analysis
54. Rescue and regulation of proboscipedia: A homeotic gene of the Antennapedia Complex
55. Developmental and molecular analysis of Deformed; a homeotic gene controlling Drosophila head development
56. D-Fos, a target gene of Decapentaplegic signalling with a critical role during Drosophila endoderm induction
57. The expression and regulation of Sex combs reduced protein in Drosophila embryos
58. The control of trunk Hox specificity and activity by Extradenticle
59. The molecular organization of the Antennapedia locus of Drosophila
60. Ectopic decapentaplegic in the Drosophila midgut alters the expression of five homeotic genes, dpp, and wingless, causing specific morphological defects
61. dpp induces mesodermal gene expression in Drosophila
62. Regulation of the Ultrabithorax gene of Drosophila by other bithorax complex genes
63. The FlyBase database of the Drosophila genome project and community literature
64. Indirect autoregulation of a homeotic Drosophila gene mediated by extracellular signaling
65. Dissection of an indirect autoregulatory response of a homeotic Drosophila gene
66. Homeotic gene expression in the visceral mesoderm of Drosophila embryos
67. A function of CBP as a transcriptional co-activator during Dpp signalling
68. Spatial regulation of Antennapedia and bithorax gene expression by the Polycomb locus in Drosophila
69. Protein products of the bithorax complex in Drosophila
70. Transcriptional repression due to high levels of Wingless signalling