Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome p450 enzymes in phenytoin-treated rats

Drug Metabolism and Disposition

Volumn 29, Issue 4 I, 2001, Pages 427-434

  Yamazaki, Hiroshi ^a   Komatsu, Tomoko ^a   Takemoto, Kei ^a   Saeki, Mayuko ^b   Minami, Yoshinori ^b   Kawaguchi, Yasuro ^b   Shimada, Noriaki ^c   Nakajima, Miki ^a   Yokoi, Tsuyoshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

^c DAIICHI PURE CHEMICALS CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; HYDROGEN PEROXIDE; HYDROPEROXIDE; PHENYTOIN; STEROID 11BETA MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CATALYSIS; DRUG CLEARANCE; HYDROXYLATION; LIVER MICROSOME; MULTIGENE FAMILY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN BINDING; RAT;

ANIMALS; ANTICONVULSANTS; BACULOVIRIDAE; BENZENE DERIVATIVES; CATECHOLS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; FLUORESCEINS; HYDROXYLATION; MALE; MICROSOMES, LIVER; NADP; OUABAIN; OXIDANTS; PHENYTOIN; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 0035060614     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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