Increased zinc absorption but not secretion in the small intestine of metallothionein-null mice

Biological Trace Element Research

Volumn 78, Issue 1-3, 2000, Pages 231-240

  Hinskens, B ^a   Philcox, J C ^a   Coyle, P ^a   Rofe, A M ^a  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

Absorption; Intestine; Metallothionein; Metallothionein null; Secretion; Zinc

Indexed keywords

ALBUMIN; METALLOTHIONEIN; ZINC; ZINC SULFATE;

ANIMAL TISSUE; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; DUODENUM; GENE EXPRESSION; GENOTYPE; ILEUM; INTESTINE ABSORPTION; INTESTINE SECRETION; JEJUNUM; MOUSE; NONHUMAN; SMALL INTESTINE;

ANIMALIA;

EID: 0035060225     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1385/BTER:78:1-3:231     Document Type: Article

References (21)

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7. Metallothionein knockout and transgenic mice exhibit altered intestinal processing of zinc with uniform zinc-dependent zinc transporter-1 expression
8. Metallothionein-null mice absorb less Zn from an egg white diet, but similar amounts from solutions, although with altered inter-tissue Zn distribution
9. Zinc homeostasis in metallothionein-null mice: Role of intestinal secretion
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11. Targetted disruption of metallothionein I and II genes increases sensitivity to cadmium
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20. Metallothionein is a component of exocrine pancreas secretion: Implications for zinc homeostasis
21. Zn-depleted mice absorb more of an intra-gastric solution of Zn than replete mice by a process enhanced by metallothionein