Activation of brainstem N-methyl-D-aspartate receptors is required for the analgesic actions of morphine given systemically

Pain

Volumn 92, Issue 1-2, 2001, Pages 129-138

  Heinricher, M M ^a,b   Schouten, J C ^a   Jobst, E E ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

3 dione disodium; 6 Cyano 7 nitroquinoxaline 2; D 2 amino 5 phosophonopentanoic acid; Microinjection; Nucleus raphe magnus; Opioid; Pain modulation

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; AMINO ACID; MORPHINE DERIVATIVE; MU OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SODIUM CHLORIDE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; BRAIN STEM; CELL ACTIVATION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; MALE; NERVE FIBER; NEUROMODULATION; NEUROTRANSMISSION; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; REFLEX; SPINAL CORD DORSAL HORN;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANALGESICS, OPIOID; ANIMALS; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MEDULLA OBLONGATA; MICROINJECTIONS; MORPHINE; NOCICEPTORS; PAIN THRESHOLD; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0035056184     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(00)00480-2     Document Type: Article

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