Real-time genotyping of cytochrome P4501A1 A4889G and T6235C polymorphisms

Molecular and Cellular Probes

Volumn 15, Issue 2, 2001, Pages 93-97

  Harth, V ^a   Bruning T ^b   Abel, J ^c   Koch, B ^a   Berg, I ^a   Sachinidis, A ^a   Bolt, H M ^b   Vetter, H ^a   Ko, Y ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^c UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

CYP1A1 polymorphisms; Real time PCR

Indexed keywords

CYTOCHROME P450 1A1;

ADULT; ARTICLE; CANCER RISK; CAUCASIAN; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ANALYSIS;

EID: 0035054037     PISSN: 08908508     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcpr.2001.0349     Document Type: Article

References (14)

1. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
2. Molecular basis of polymorphic drug metabolism
3. Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility: A review
4. Assignment of the human 2,4,7, 8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 gene to chromosome 15
5. Human dioxin-inducible cytochrome 1-450: Complementary DNA and amino acid sequence
6. Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
7. Characterization of human lung microsomal cytochrome P450 1A1 and its role in oxidation of chemical carcinogens
8. Contribution of genetic and nutritional factors to DNA damage in heavy smokers
9. Polycyclic aromatic hydrocarbon-DNA adducts in human placenta and modulation by CYP1A1 induction and genotype
10. Genetic linkage of lung cancer-associated Mspl polymorphisms with amino acid replacement in the heme binding region of the human cytochrome P4501A1 gene
11. Detection of CYP1A1 gene polymorphism using designed RFLP and distributions of CYP1A1 genotypes in Japanese
12. Rapid analysis of GSTM1, GSTT1 and GSTP1 polymorphisms using real-time polymerase chain reaction
13. A casecontrol study of cytochrome P450 1A1, glutathione S-transferase M1, cigarette smoking and lung cancer susceptibility (Massachusetts United States)
14. Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens