메뉴 건너뛰기




Volumn 18, Issue 3, 1997, Pages 503-509

Contribution of genetic and nutritional factors to DNA damage in heavy smokers

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; BETA CAROTENE; DNA; GLUTATHIONE TRANSFERASE; POLYCYCLIC AROMATIC HYDROCARBON; RETINOL; TRACE ELEMENT; VALINE;

EID: 0031417557     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.3.503     Document Type: Article
Times cited : (140)

References (54)
  • 1
    • 0009040854 scopus 로고
    • The role of molecular epidemiology in cancer prevention
    • DeVita, V.T., Jr, Hellman, S. and Rosenberg, S.A. (eds), J.B. Lippincott, Philadelphi, PA
    • Perera, F.P. and Mooney, L.A. (1993) The role of molecular epidemiology in cancer prevention. In DeVita, V.T., Jr, Hellman, S. and Rosenberg, S.A. (eds), Cancer Prevention. J.B. Lippincott, Philadelphi, PA, pp. 1-15.
    • (1993) Cancer Prevention , pp. 1-15
    • Perera, F.P.1    Mooney, L.A.2
  • 2
    • 0015682899 scopus 로고
    • Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma
    • Kellerman, G., Shaw, C.R. and Kellermann, M.L. (1973) Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma. New Engl. J. Med., 289, 934-937.
    • (1973) New Engl. J. Med. , vol.289 , pp. 934-937
    • Kellerman, G.1    Shaw, C.R.2    Kellermann, M.L.3
  • 3
    • 0020385021 scopus 로고
    • Positive correlation between high aryl hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes
    • Kouri, R.E., McKinney, C.E., Slomiany, D.J., Snodgrass, D.R., Wray, N.P. and McLemore, T.L. (1982) Positive correlation between high aryl hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes. Cancer Res., 45, 5030-5037.
    • (1982) Cancer Res. , vol.45 , pp. 5030-5037
    • Kouri, R.E.1    McKinney, C.E.2    Slomiany, D.J.3    Snodgrass, D.R.4    Wray, N.P.5    McLemore, T.L.6
  • 4
    • 0025938214 scopus 로고
    • Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose
    • Nakachi, K., Imai, K., Hayashi, S., Watanabe, J. and Kawajiri, K. (1991) Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res., 51, 5177-5180.
    • (1991) Cancer Res. , vol.51 , pp. 5177-5180
    • Nakachi, K.1    Imai, K.2    Hayashi, S.3    Watanabe, J.4    Kawajiri, K.5
  • 5
    • 0026785516 scopus 로고
    • High susceptibility to lung cancer analyzed in terms of combined genotype of P450IA1 and Mu-class glutathione S-transferase genes
    • Hayashi, S., Watanabe, J. and Kawajiri, K. (1992) High susceptibility to lung cancer analyzed in terms of combined genotype of P450IA1 and Mu-class glutathione S-transferase genes. Jpn. J. Cancer Res., 83, 866-870.
    • (1992) Jpn. J. Cancer Res. , vol.83 , pp. 866-870
    • Hayashi, S.1    Watanabe, J.2    Kawajiri, K.3
  • 7
    • 0028182661 scopus 로고
    • I462V mutation in the human CYP1A1 gene: Lack of correlation with either the Msp I 1.9kb (M2) allele or Cyp1A1 inducibility in a three-generation family of East Mediterranean descent
    • Wedlund, P.J., Kimura, S., Gonzalez, F.J. and Nebert, D.W. (1994) I462V mutation in the human CYP1A1 gene: lack of correlation with either the Msp I 1.9kb (M2) allele or Cyp1A1 inducibility in a three-generation family of East Mediterranean descent. Pharmacogenetics, 4, 21-26.
    • (1994) Pharmacogenetics , vol.4 , pp. 21-26
    • Wedlund, P.J.1    Kimura, S.2    Gonzalez, F.J.3    Nebert, D.W.4
  • 10
    • 0025523339 scopus 로고
    • Individual differences in lung cancer susceptibility in relation to polymorphisms of P-450IA1 gene and cigarette dose
    • Kawajiri, K., Nakachi, K., Imai, K., Hayashi, S. and Watanabe, J. (1990) Individual differences in lung cancer susceptibility in relation to polymorphisms of P-450IA1 gene and cigarette dose. Int. Symp. Princess Takamatsu Cancer Res. Fund, 21, 55-61.
    • (1990) Int. Symp. Princess Takamatsu Cancer Res. Fund , vol.21 , pp. 55-61
    • Kawajiri, K.1    Nakachi, K.2    Imai, K.3    Hayashi, S.4    Watanabe, J.5
  • 11
    • 0028859929 scopus 로고
    • The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1), rather than the rsal polymorphism of IIE1 (CypIIE1), is associated with lung cancer in Rio de Janeiro
    • Hamada., G.S. et al. (1995) The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1), rather than the rsal polymorphism of IIE1 (CypIIE1), is associated with lung cancer in Rio de Janeiro. Cancer Epidemiol. Biomarkers Prevent., 4, 63-67.
    • (1995) Cancer Epidemiol. Biomarkers Prevent. , vol.4 , pp. 63-67
    • Hamada, G.S.1
  • 12
    • 0026921501 scopus 로고
    • Point-mutational MspI and Ile-Val polymorphism closely linked in the CYP1A1 gene: Lack of association with susceptibility to lung cancer in a Finnish study population
    • Hirvonen, A., Husgafvel-Pursiainen, K., Karjalainen, A., Anttila, S. and Vainio, H. (1992) Point-mutational MspI and Ile-Val polymorphism closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. Cancer Epidemiol. Biomarkers Prevent., 1, 485-489.
    • (1992) Cancer Epidemiol. Biomarkers Prevent. , vol.1 , pp. 485-489
    • Hirvonen, A.1    Husgafvel-Pursiainen, K.2    Karjalainen, A.3    Anttila, S.4    Vainio, H.5
  • 13
    • 0026240167 scopus 로고
    • Human CYP1A1 (cytochrome P450) gene: Lack of association between the Mspl restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population
    • Tefre, T., Ryberg, D., Haugen, A., Nebert, D.W., Skaug, V., Brogger, A. and Borresen, A. (1991) Human CYP1A1 (cytochrome P450) gene: lack of association between the Mspl restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. Pharmacogenetics, 1, 20-25.
    • (1991) Pharmacogenetics , vol.1 , pp. 20-25
    • Tefre, T.1    Ryberg, D.2    Haugen, A.3    Nebert, D.W.4    Skaug, V.5    Brogger, A.6    Borresen, A.7
  • 15
    • 0025058262 scopus 로고
    • Isoenzyme(s) of glutathione transferase (class mu) as a marker for the susceptibility to lung cancer: A follow-up study
    • Seidegard, J., Pero, R.W., Markowitz, M.M., Roush, G., Miller, D.G. and Beattie, E.J. (1990) Isoenzyme(s) of glutathione transferase (class mu) as a marker for the susceptibility to lung cancer: a follow-up study. Carcinogenesis, 11, 33-36.
    • (1990) Carcinogenesis , vol.11 , pp. 33-36
    • Seidegard, J.1    Pero, R.W.2    Markowitz, M.M.3    Roush, G.4    Miller, D.G.5    Beattie, E.J.6
  • 16
    • 0025778695 scopus 로고
    • Glutathione S-transferase mu locus: Use of genotyping and phenotyping assays to assess association with lung cancer susceptibility
    • Zhong, S., Howie, A.F., Ketterer, B., Taylor, J., Hayes, J.D., Beckett, G.J., Wathen, C.G., Wolf, C.R. and Spurr, N.K. (1991) Glutathione S-transferase mu locus: use of genotyping and phenotyping assays to assess association with lung cancer susceptibility. Carcinogenesis, 9, 1533-1537.
    • (1991) Carcinogenesis , vol.9 , pp. 1533-1537
    • Zhong, S.1    Howie, A.F.2    Ketterer, B.3    Taylor, J.4    Hayes, J.D.5    Beckett, G.J.6    Wathen, C.G.7    Wolf, C.R.8    Spurr, N.K.9
  • 17
    • 0028168178 scopus 로고
    • Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: A study on host factors in relation to age at onset, gender and histological cancer types
    • Alexandrie, A.K., Sundberg, M.I., Seidegard, J., Tornling, G. and Rannug, A. (1994) Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: a study on host factors in relation to age at onset, gender and histological cancer types. Carcinogenesis, 15, 1785-1790.
    • (1994) Carcinogenesis , vol.15 , pp. 1785-1790
    • Alexandrie, A.K.1    Sundberg, M.I.2    Seidegard, J.3    Tornling, G.4    Rannug, A.5
  • 18
    • 0027067889 scopus 로고
    • Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: Application to glutathione transferase
    • Bell, D.A., Thompson, C.L., Taylor, J., Clark, G., Miller, C.R., Perera, F., Hsieh, L. and Lucier, G.W. (1992) Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: application to glutathione transferase. Environ. Hlth Perspect., 98, 113-117.
    • (1992) Environ. Hlth Perspect. , vol.98 , pp. 113-117
    • Bell, D.A.1    Thompson, C.L.2    Taylor, J.3    Clark, G.4    Miller, C.R.5    Perera, F.6    Hsieh, L.7    Lucier, G.W.8
  • 19
    • 0023756891 scopus 로고
    • Protective role of glutathione and glutathione transferases in mutagenesis and carcinogenesis
    • Ketterer, B. (1988) Protective role of glutathione and glutathione transferases in mutagenesis and carcinogenesis. Mutat. Res., 202, 343-361.
    • (1988) Mutat. Res. , vol.202 , pp. 343-361
    • Ketterer, B.1
  • 20
    • 0026888485 scopus 로고
    • The data support a role for antioxidants in reducing cancer risk
    • Block, G. (1992) The data support a role for antioxidants in reducing cancer risk. Nutr. Rev., 50, 207-213.
    • (1992) Nutr. Rev. , vol.50 , pp. 207-213
    • Block, G.1
  • 22
    • 0027194346 scopus 로고
    • Vitamin E and smoking and the risk of lung cancer
    • Knekt, P. (1993) Vitamin E and smoking and the risk of lung cancer. Annls NY Acad. Sci., 686, 280-288.
    • (1993) Annls NY Acad. Sci. , vol.686 , pp. 280-288
    • Knekt, P.1
  • 23
    • 0002726987 scopus 로고
    • Diet as a factor in the etiology and prevention of lung cancer
    • In Samet, J.M. (ed.), Marcel Dekker, New York, NY
    • Byers, T. (1994) Diet as a factor in the etiology and prevention of lung cancer. In Samet, J.M. (ed.), Epidemiology of Lung Cancer. Marcel Dekker, New York, NY, pp. 335-352.
    • (1994) Epidemiology of Lung Cancer , pp. 335-352
    • Byers, T.1
  • 24
    • 0028207272 scopus 로고
    • Micronutrients and cancer risk
    • Willett, W.C. (1994) Micronutrients and cancer risk. Am. J. Clin. Nutr., 59 (suppl.), 1162S-1165S.
    • (1994) Am. J. Clin. Nutr. , vol.59 , Issue.SUPPL.
    • Willett, W.C.1
  • 25
    • 0028138821 scopus 로고
    • Polycyclic aromatic hydrocarbon-DNA adducts in smokers and their relationship to micronutrient levels and glutathione S-transferase M1 genotype
    • Grinberg Funes, R.A., Singh, V.N., Perera, F.P., Bell, D.A., Young, T.L., Dickey, C., Wang, L.W. and Santella, R.M. (1994) Polycyclic aromatic hydrocarbon-DNA adducts in smokers and their relationship to micronutrient levels and glutathione S-transferase M1 genotype. Carcinogenesis, 15, 2449-2454.
    • (1994) Carcinogenesis , vol.15 , pp. 2449-2454
    • Grinberg Funes, R.A.1    Singh, V.N.2    Perera, F.P.3    Bell, D.A.4    Young, T.L.5    Dickey, C.6    Wang, L.W.7    Santella, R.M.8
  • 26
    • 0028567143 scopus 로고
    • Carcinogen-DNA adducts and gene mutation in foundry workers with low level exposure to polycyclic aromatic hydrocarbons
    • Perera, F.P. et al. (1994) Carcinogen-DNA adducts and gene mutation in foundry workers with low level exposure to polycyclic aromatic hydrocarbons. Carcinogenesis, 15, 2905-2910.
    • (1994) Carcinogenesis , vol.15 , pp. 2905-2910
    • Perera, F.P.1
  • 27
    • 0026613710 scopus 로고
    • Molecular and genetic damage from environmental pollution in Poland
    • Perera, F.P. et al. (1992) Molecular and genetic damage from environmental pollution in Poland. Nature, 360, 256-258.
    • (1992) Nature , vol.360 , pp. 256-258
    • Perera, F.P.1
  • 28
    • 0029086358 scopus 로고
    • Decline in DNA damage and other biomarkers in peripheral blood following smoking cessation
    • Mooney, L.A. et al. (1995) Decline in DNA damage and other biomarkers in peripheral blood following smoking cessation. Cancer Epidemiol. Biomarkers Prevent., 4, 627-634.
    • (1995) Cancer Epidemiol. Biomarkers Prevent. , vol.4 , pp. 627-634
    • Mooney, L.A.1
  • 29
    • 0029000008 scopus 로고
    • A case-control molecular epidemiologic study of lung cancer
    • Tang, D. et al. (1995) A case-control molecular epidemiologic study of lung cancer. Cancer Epidemiol. Biomarkers Prevent., 4, 341-346.
    • (1995) Cancer Epidemiol. Biomarkers Prevent. , vol.4 , pp. 341-346
    • Tang, D.1
  • 30
    • 0016747769 scopus 로고
    • Clonidine in alcohol withdrawal
    • Bjorkquist, S.E. (1975) Clonidine in alcohol withdrawal. Acta Paediat. Scand., 52, 256-263.
    • (1975) Acta Paediat. Scand. , vol.52 , pp. 256-263
    • Bjorkquist, S.E.1
  • 31
    • 0018097616 scopus 로고
    • Clonidine in opiate withdrawal
    • Gold, M.S., Redmond, D.E. and Kleber, H.D. (1978) Clonidine in opiate withdrawal. Lancet, i, 929-930.
    • (1978) Lancet , vol.1 , pp. 929-930
    • Gold, M.S.1    Redmond, D.E.2    Kleber, H.D.3
  • 32
    • 0021674627 scopus 로고
    • Cigarette craving, smoking withdrawl, and clonidine
    • Glassman, A.H., Jackson, W.K. and Walsh, B.T. (1984) Cigarette craving, smoking withdrawl, and clonidine. Science, 226, 864-866.
    • (1984) Science , vol.226 , pp. 864-866
    • Glassman, A.H.1    Jackson, W.K.2    Walsh, B.T.3
  • 33
    • 0023910021 scopus 로고
    • Detection of polycyclic aromatic hydrocarbon-DNA adducts in white blood cells of foundry workers
    • Perera, F.P., Hemminki, K., Young, T.L., Brenner, D., Kelly, G. and Santella, R.M. (1988) Detection of polycyclic aromatic hydrocarbon-DNA adducts in white blood cells of foundry workers. Cancer Res., 48, 2288-2291.
    • (1988) Cancer Res. , vol.48 , pp. 2288-2291
    • Perera, F.P.1    Hemminki, K.2    Young, T.L.3    Brenner, D.4    Kelly, G.5    Santella, R.M.6
  • 34
    • 0022588849 scopus 로고
    • The determination of nicotine and cotinine in plasma
    • Davis, R.A. (1986) The determination of nicotine and cotinine in plasma. J. Chromatogr. Sci., 24, 134-141.
    • (1986) J. Chromatogr. Sci. , vol.24 , pp. 134-141
    • Davis, R.A.1
  • 36
    • 0027306050 scopus 로고
    • Genetic risk and carcinogen exposure: A common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer
    • Bell, D.A., Taylor, J.A., Paulson, D.F., Robertson, C.N., Mohler, J.L. and Lucier, G.W. (1993) Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. J. Natl Cancer Inst., 85, 1159-1164.
    • (1993) J. Natl Cancer Inst. , vol.85 , pp. 1159-1164
    • Bell, D.A.1    Taylor, J.A.2    Paulson, D.F.3    Robertson, C.N.4    Mohler, J.L.5    Lucier, G.W.6
  • 37
    • 0026509087 scopus 로고
    • Maternal vitamin levels during pregnancies producing infants with neural tube defects
    • Mills, J.L. et al. (1992) Maternal vitamin levels during pregnancies producing infants with neural tube defects. J. Pediat., 120, 863-871.
    • (1992) J. Pediat. , vol.120 , pp. 863-871
    • Mills, J.L.1
  • 38
    • 0029806936 scopus 로고    scopus 로고
    • Preferential formation of benzo(a)pyrene adducts at lung cancer mutational hotspots in P53
    • Denissenko, M.F., Pao, A., Tang, M. and Pfeifer, G.P. (1996) Preferential formation of benzo(a)pyrene adducts at lung cancer mutational hotspots in P53. Science, 274, 430-432.
    • (1996) Science , vol.274 , pp. 430-432
    • Denissenko, M.F.1    Pao, A.2    Tang, M.3    Pfeifer, G.P.4
  • 41
    • 0019137319 scopus 로고
    • Inhibition by L-ascorbate of binding to DNA or BaP and its metabolites
    • Shah, G.M. and Bhattacharya, R.K. (1980) Inhibition by L-ascorbate of binding to DNA or BaP and its metabolites. Ind. J. Biochem. Biophys., 17, 96-98.
    • (1980) Ind. J. Biochem. Biophys. , vol.17 , pp. 96-98
    • Shah, G.M.1    Bhattacharya, R.K.2
  • 42
    • 0018831870 scopus 로고
    • Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C
    • Kallistratos, G. and Fasske, E. (1980) Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C. J. Cancer Res. Clin. Oncol., 97, 91-96.
    • (1980) J. Cancer Res. Clin. Oncol. , vol.97 , pp. 91-96
    • Kallistratos, G.1    Fasske, E.2
  • 43
    • 0024433924 scopus 로고
    • Induction of glutathione-S-transferase activity by antioxidants in hepatocyte culture
    • Chen, L.H. and Chih-Chii, A.S. (1989) Induction of glutathione-S-transferase activity by antioxidants in hepatocyte culture. Anticancer Res., 9, 1069-1072.
    • (1989) Anticancer Res. , vol.9 , pp. 1069-1072
    • Chen, L.H.1    Chih-Chii, A.S.2
  • 45
    • 0002020447 scopus 로고
    • Cellular biology and biochemistry of the retinoids
    • Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds), Raven Press, New York, NY
    • Gudas, L.J., Sporn, M.B. and Roberts, A.B. (1994) Cellular biology and biochemistry of the retinoids. In Sporn, M.B., Roberts, A.B. and Goodman, D.S. (eds), The Retinoids, Biology, Chemistry, and Medicine, 2nd Edn. Raven Press, New York, NY, pp. 443-520.
    • (1994) The Retinoids, Biology, Chemistry, and Medicine, 2nd Edn. , pp. 443-520
    • Gudas, L.J.1    Sporn, M.B.2    Roberts, A.B.3
  • 47
    • 0029009951 scopus 로고
    • Human lung carcinogen-DNA adduct levels mediated by genetic polymorphisms in vivo
    • Kato, S., Bowman, E.D., Harrington, A.M., Blomeke, B. and Shields, P.G. (1995) Human lung carcinogen-DNA adduct levels mediated by genetic polymorphisms in vivo. JNCI, 87, 902-907.
    • (1995) JNCI , vol.87 , pp. 902-907
    • Kato, S.1    Bowman, E.D.2    Harrington, A.M.3    Blomeke, B.4    Shields, P.G.5
  • 48
    • 0026592561 scopus 로고
    • Dietary effects on cytochromes P450, xenobiotic metabolism, and toxicity
    • Yang, C.S., Brady, J.F. and Hong, J.Y. (1992) Dietary effects on cytochromes P450, xenobiotic metabolism, and toxicity. FASEB J., 6, 737-744.
    • (1992) FASEB J. , vol.6 , pp. 737-744
    • Yang, C.S.1    Brady, J.F.2    Hong, J.Y.3
  • 49
    • 0005383917 scopus 로고
    • Vitamin A as an antioxidant in vitro and in vivo
    • Livrea, M.A. and Packer, L. (eds), Birkhauser Verlag, Basel, Switzerland
    • Livrea, M.A. and Packer, L. (1994) Vitamin A as an antioxidant in vitro and in vivo. In Livrea, M.A. and Packer, L. (eds), Retinoids: From Basic Science to Clinical Applications. Birkhauser Verlag, Basel, Switzerland, pp. 293-304.
    • (1994) Retinoids: from Basic Science to Clinical Applications , pp. 293-304
    • Livrea, M.A.1    Packer, L.2
  • 50
    • 0027220611 scopus 로고
    • Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes
    • Shields, P.G., Bowman, E.D., Harrington, A.M., Doan, V.T. and Weston, A. (1993) Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes. Cancer Res., 53, 3486-3492.
    • (1993) Cancer Res. , vol.53 , pp. 3486-3492
    • Shields, P.G.1    Bowman, E.D.2    Harrington, A.M.3    Doan, V.T.4    Weston, A.5
  • 51
    • 0028818149 scopus 로고
    • The impact of glutathione S-transferase M1 and cytochrome P450 1A1 genotypes on white blood cell polycyclic aromatic hydrocarbon-DNA adduct levels in humans
    • Rothman, N., Shields, P.G., Poirier, M.C., Harrington, A.M., Ford, D.P. and Strickland, P.T. (1995) The impact of glutathione S-transferase M1 and cytochrome P450 1A1 genotypes on white blood cell polycyclic aromatic hydrocarbon-DNA adduct levels in humans. Mol. Carcinogen., 14, 63-68.
    • (1995) Mol. Carcinogen. , vol.14 , pp. 63-68
    • Rothman, N.1    Shields, P.G.2    Poirier, M.C.3    Harrington, A.M.4    Ford, D.P.5    Strickland, P.T.6
  • 53
    • 0029998738 scopus 로고    scopus 로고
    • Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes
    • Duthie, S.J., Ma, A., Ross, M.A. and Collins, A.R. (1996) Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes. Cancer Res., 56, 1291-1295.
    • (1996) Cancer Res. , vol.56 , pp. 1291-1295
    • Duthie, S.J.1    Ma, A.2    Ross, M.A.3    Collins, A.R.4
  • 54
    • 0010607277 scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
    • Alpha-Tocopherol BCCPSG (1994) The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. New Engl. J. Med., 330, 1029-1035.
    • (1994) New Engl. J. Med. , vol.330 , pp. 1029-1035


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.