Coxsackievirus-adenovirus receptor expression in ovarian cancer cell lines is associated with increased adenovirus transduction efficiency and transgene expression

Cancer Gene Therapy

Volumn 8, Issue 3, 2001, Pages 168-175

  You, Zongbing ^a   Fischer, Dagmar C ^a   Tong, Xiaowen ^a   Hasenburg, Annette ^a   Aguilar Cordova, Estuardo ^b   Kieback, Dirk G ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Adenovirus mediated thymidine kinase (adv rsv tk); Coxsackievirus adenovirus receptor (CAR); Integrin v 3; Integrin v 5; Ovarian cancer cell lines

Indexed keywords

ESTRADIOL; GANCICLOVIR; INTEGRIN; THYMIDINE KINASE; VIRUS RECEPTOR;

ADENOVIRUS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION FUNCTION; COXSACKIE VIRUS; DOSE RESPONSE; FLOW CYTOMETRY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; VIRUS GENE;

ADENOVIRIDAE; COXSACKIEVIRUS;

EID: 0035050302     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700284     Document Type: Article

References (39)

1. Management of epithelial ovarian cancer
2. Direct in vivo gene transfer and expression in malignant cells using adenovirus vectors
3. Adenovirus vectors for gene therapy
4. Adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene selectivity sensitivities human ovarian carcinoma cells to ganciclovir
5. Differential sensitivity of thoracic malignant tumors to adenovirus-mediated drug sensitization gene therapy
6. Adenovirus-mediated gene therapy of ovarian cancer in a mouse model
7. The efficacy of adenovirus-mediated gene therapy of ovarian cancer is enhanced by using the cytomegalovirus promoter
8. Human epithelial ovarian cancer xenotransplants into nude mice can be cured by adenovirus-mediated thymidine kinase gene therapy
9. Adenovirus-mediated p53 tumor suppressor gene therapy of human ovarian carcinoma
10. Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer
11. Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase I clinical trial in malignant mesothelioma
12. Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5
13. The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses
14. HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
15. Adenovirus type 5 fiber knob binds to MHC class I α2 domain at the surface of human epithelial and B lymphoblastoid cells
16. Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment
17. Infectious entry pathway of adenovirus type 2
18. Nuclear import and export of viruses and virus genomes
19. Characterization and properties of nine human ovarian adenocarcinoma cell lines
20. Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma cell lines
21. Estrogen and antiestrogen effects on the growth of human epithelial ovarian cancer in vitro
22. Adenovirus-mediated thymidine kinase gene transduction in human epithelial ovarian cancer cell lines followed by exposure to ganciclovir
23. A monoclonal antibody specific for the cellular receptor for the group B coxsackieviruses
24. Upregulation of integrins αvβ3 and αvβ5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene therapy
25. Polarization of the α6β4 integrin in ovarian carcinomas
26. A single locus on human chromosome 21 directs the expression of a receptor for adenovirus type 2 in mouse A9 cells
27. The coxsackievirus adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F
28. Coxsackievirus and adenovirus receptor cytoplasmic and transmembrane domains are not essential for coxsackievirus and adenovirus infection
29. Integrins: Versatility, modulation, and signalling in cell adhesion
30. Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin
31. Integrin alpha v beta 3 expression by bone-residing breast cancer metastases
32. The integrin β1 subunit associates with the vitronectin receptor αv subunit to form a novel vitronectin receptor in a human embryonic kidney cell line
33. Loss of adenoviral receptor expression in human bladder cancer cells: A potential impact on the efficacy of gene therapy
34. The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cess cultures
35. Adenovirus vector-based purging of multiple myeloma cells
36. Differential susceptibility of primary and established human glioma cells to adenovirus infection: Targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer
37. Expression of the primary coxsackie and adenovirus receptor is downregulated during skeletal muscle maturation and limits the efficacy of adenovirus-mediated gene delivery to muscle cells
38. Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer
39. An interaction between penton base and alpha v integrins plays a minimal role in adenovirus-mediated gene transfer to hepatocytes in vitro and in vivo