Proadrenomedullin N-terminal 20 peptide (PAMP) inhibits food intake and gastric emptying in mice

Peptides

Volumn 22, Issue 4, 2001, Pages 589-595

  Ohinata, Kousaku ^a   Inui, Akio ^b   Asakawa, Akihiro ^b   Wada, Keiji ^c   Wada, Etsuko ^c   Yoshikawa, Masaaki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KOBE UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Bombesin; Food intake; Gastric emptying; Proadrenomedullin N terminal 20 peptide (PAMP)

Indexed keywords

BOMBESIN; BOMBESIN ANTAGONIST; BOMBESIN RECEPTOR; GASTRIN RELEASING PEPTIDE; PROADRENOMEDULLIN; RECEPTOR SUBTYPE;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SELECTIVITY; FEEDING BEHAVIOR; FOOD INTAKE; HUMAN; HYPERGLYCEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOMACH EMPTYING;

ADRENOMEDULLIN; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY INTAKE; GASTRIC EMPTYING; HUMANS; INJECTIONS, INTRAVENTRICULAR; MICE; MICE, KNOCKOUT; PEPTIDE FRAGMENTS; PEPTIDES; PROTEINS; RECEPTORS, BOMBESIN;

EID: 0035047604     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00368-0     Document Type: Article

References (32)

1. Isolation and structure of bombesin and alytesin, 2 analogous active peptides from the skin of the European amphibians Bombina and Alytes
2. Effects of adrenomedullin and proadrenomedullin N-terminal 20 peptide on rat zona glomerulosa cells
3. Urocortin reduces food intake and gastric emptying in lean and ob/ob obese mice
4. Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells
5. BRS-3: A novel bombesin receptor subtype selectively expressed in testis and lung carcinoma cells
6. Molecular cloning of a new bombesin receptor subtype expressed in uterus during pregnancy
7. Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice
8. Specific binding sites for proadrenomedullin N-terminal 20 peptide (PAMP) in the rat
9. Identification and hypotensive activity of proadrenomedullin N-terminal 20 peptide (PAMP)
10. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin
11. Peptide growth factors and their receptors
12. Peptide structural requirements for antagonism differ between the two mammalian bombesin receptor subtypes
13. Central action of adrenomedullin to inhibit gastric emptying in rats
14. Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue
15. Neuromedin B: A novel bombesin-like peptide identified in porcine spinal cord
16. Neuromedin C: A bombesin-like peptide identified in porcine spinal cord
17. 2-terminal 20 peptide (PAMP) and adrenomedullin bind to teratocarcinoma cells
18. Cholecystokinin suppresses food intake by inhibiting gastric emptying
19. Effects of pancreatic polypeptide family peptides on feeding and learning behavior in mice
20. Proadrenomedullin N-terminal 20 peptide (PAMP) elevates blood glucose levels via bombesin receptor in mice
21. Functional properties of two bombesin-like peptide receptors revealed by the analysis of mice lacking neuromedin B receptor
22. Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity
23. Centrally administered bombesin affects gastric emptying and small and large bowel transit in the rat
24. Centrally-mediated bombesin effects on gastrointestinal motility
25. 2-terminal 20 peptide, a new product of the adrenomedullin gene, inhibits norepinephrine overflow from nerve endings
26. Cloning and functional characterization of a complementary DNA encoding the murine fibroblast bombesin/gastrin-releasing peptide receptor
27. Expression of adrenomedullin mRNA in the human brain and pituitary
28. Adrenomedullin inhibits feeding in the rat by a mechanism involving calcitonin gene-related peptide receptors
29. Decreased food intake and body weight in pancreatic polypeptide-overexpressing mice
30. Potent bombesin receptor antagonists distinguish receptor subtypes
31. Generation and characterization of mice lacking gastrin-releasing peptide receptor
32. cDNA cloning, characterization, and brain region-specific expression of a neuromedin-B-preferring bombesin receptor