Animal-derived or synthetic surfactant for the treatment of neonatal respiratory distress syndrome: A review

Acta Paediatrica, International Journal of Paediatrics, Supplement

Volumn 90, Issue 436, 2001, Pages 25-27

  Milligan, D W A ^a   Ainsworth, S B ^a  

^a ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

Exogenous surfactant; Newborn; Respiratory distress syndrome

Indexed keywords

APOSURF; ARTIFICIAL LUNG SURFACTANT; BLES; LUCINACTANT; LUNG SURFACTANT EXTRACT; LUSUPULTIDE; SURFACTANT; SURFACTANT TA; TURFSURF; UNCLASSIFIED DRUG;

AMNION FLUID; ANIMAL MODEL; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SYNTHESIS; GAS EXCHANGE; HUMAN; IN VITRO STUDY; LUNG ALVEOLUS SURFACE TENSION; LUNG FUNCTION; LUNG LAVAGE; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEWBORN MORTALITY; NONHUMAN; PREMATURITY; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 0035046872     PISSN: 08035326     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2001.tb01625.x     Document Type: Article

References (32)

1. Natural vs synthetic surfactants in neonatal respiratory distress syndrome
2. Natural surfactant extract versus synthetic surfactant for neonatal respiratory distress syndrome
3. The pulmonary surfactant system: Biochemical and clinical aspects
4. Pulmonary surfactant: Functions and molecular composition
5. Molecular structures and interactions of pulmonary surfactant components
6. Lung surfactant proteins A and D in innate immune defense
7. The efficacy and safety of KL4-surfactant in preterm infants with respiratory distress syndrome
8. Comparison of rSP-C surfactant with natural and synthetic surfactants after late treatment in a rat model of the acute respiratory distress syndrome
9. Biophysical properties of protein-free, totally synthetic surfactants, ALEC and Exosurf, in comparison with surfactant TA
10. Comparison of surface properties and physiological effects of a synthetic and natural surfactant in preterm rabbits
11. Surfactant inhibition by plasma proteins: Differential sensitivity of various surfactant preparations
12. Resistance of new recombinant surfactant preparations to inhibition by meconium
13. A controlled clinical comparison of four different surfactant preparations in surfactant-deficient preterm lambs
14. Treatment responses to surfactants containing natural surfactant proteins in preterm rabbits
15. Effects of suffactant protein-A on surfactant function in preterm ventilated rabbits
16. Different ventilation strategies alter surfactant responses in preterm rabbits
17. Lung function, surfactant apoprotein content, and level of PEEP in prematurely delivered rabbits
18. Positive end-expiratory pressure preserves surfactant function in preterm lambs
19. Changes in exogenous surfactant in ventilated preterm lamb lungs
20. Static respiratory compliance in the newborn. III: Early changes after exogenous surfactant treatment
21. Randomized trial examining cerebral haemodynamics following artificial or animal surfactant
22. Clinical trial of Survanta vs Exosurf therapy in infants < 1500 g with respiratory distress syndrome
23. A randomized trial comparing Exosurf vs. Survanta in the treatment of neonatal RDS
24. A multicenter randomized trial comparing two surfactants for the treatment of respiratory distress syndrome
25. Modified bovine surfactant (Survanta) versus a protein-free surfactant (Exosurf) in the treatment of respiratory distress syndrome in preterm infants: A pilot study
26. A multicenter randomized masked comparison trial of natural versus synthetic surfactant for the treatment of respiratory distress syndrome
27. A multicenter, randomized trial comparing synthetic surfactant to modified bovine surfactant in the treatment of neonatal respiratory distress syndrome
28. A multicenter randomized masked comparison trial of synthetic surfactant versus calf lung surfactant extract for the prevention of neonatal respiratory distress syndrome
29. Comparative efficacy of Exosurf and Survanta surfactants on early clinical course of respiratory distress syndrome and complications of prematurity
30. Comparative trial of artificial and natural surfactants in the treatment of respiratory distress syndrome of prematurity: Experiences in a developing country
31. Pumactant and poractant alfa for the treatment of respiratory distress syndrome in neonates born at 25 to 29 weeks' gestation: A randomised trial
32. Randomised trial comparing natural and synthetic surfactant: Increased risk of infection after natural surfactant?