Progression of esophageal carcinoma by loss of EGH-STAT1 pathway

Cancer Journal

Volumn 7, Issue 2, 2001, Pages 132-139

  Watanabe, G ^a   Kaganoi, J ^a   Imamura, M ^a   Shimada, Y ^a   Itami, A ^a   Uchida, S ^a   Sato, F ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

EGF; Esophageal cancer; Signal transduction; STAT; Tumor suppressor

Indexed keywords

EPIDERMAL GROWTH FACTOR; STAT PROTEIN;

ARTICLE; CANCER GROWTH; CELL CULTURE; ESOPHAGUS CARCINOMA; GENE EXPRESSION; HUMAN; HUMAN CELL; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

BLOTTING, NORTHERN; CARCINOMA, SQUAMOUS CELL; DISEASE PROGRESSION; DNA-BINDING PROTEINS; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

EID: 0035044641     PISSN: 15289117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Estimates of the worldwide incidence of eighteen major cancers in 1985
2. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
3. Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
4. Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
5. WAF1/CIP1 mediated by STAT1
6. Activation of Stat1 by mutant fibroblast growth factor-receptor in thanatophoric dysplasia type II dwarfism
7. Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
8. Cytokine receptor signalling
9. Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter
10. Activation of transcription by IFN-γ: Tyrosine phosphorylation of a 91-kD DNA binding protein
11. Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear poretargeting complex formation with NPI-1, but not Rch1
12. Inhibitors of mammalian G1 cyclin-dependent kinases
13. Common nuclear signal transduction pathway activated by growth factor and cytokine receptors
14. Epidermal growth factor
15. Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor
16. Radioimmunoassay of human epidermal growth factor-hEGF levels in human body fluids
17. Characterization of 21 newly established esophageal cancer cell lines
18. Prognostic significance of cell culture in carcinoma of the esophagus
19. A simplified method for the routine culture of normal oral epithelial (NOE) cells from upper aerodigestive tract mucosa
20. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
21. In oesophageal squamous cell carcinoma vascular endothelial growth factor is associated with p53 mutation, advanced stage and poor prognosis
22. Decreased expression and rare somatic mutation of the CIP1/WAF1 gene in human hepatocellular carcinoma
23. Growth effects of epidermal growth factor and overexpression of its receptors on human squamous cell carcinomas in culture
24. Anitisense oligonucleotides of WAF1 gene prevents EGF-induced cell-cycle arrest in A431 cells
25. Epidermal growth factor-like proteins in breast fluid and human milk
26. Genetic determinants of p53-induced apoptosis and growth arrest
27. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
28. Lessons from hereditary colorectal cancer
29. TGF-beta signal transduction
30. Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms
31. Effect of cigarette smoking on salivary epidermal growth factor (EGF) and EGF receptor in human buccal mucosa