Recognition and oxidative metabolism of cyclodipeptides by hepatic cytochrome P450

Peptides

Volumn 22, Issue 4, 2001, Pages 557-565

  Delaforge, Marcel ^a   Bouillé, Geneviève ^a   Jaouen, Maryse ^b   Jankowski, Christopher K ^d   Lamouroux, Christine ^d   Bensoussan, Claude ^c  

^a CEA SACLAY   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Rhodia Europe   (France)

^d UNIVERSITÉ DE MONCTON   (Canada)

Author keywords

Active site binding; Amino acids; Cyclopeptides; Cytochrome P450 3A; Diketopiperazine; Peptides

Indexed keywords

3 METHYLCHOLANTHRENE; CLOFIBRATE; CYCLOPEPTIDE; CYTOCHROME P450; CYTOCHROME P450 3A; DEXAMETHASONE; DIPEPTIDE; PHENOBARBITAL;

AEROBIC METABOLISM; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HUMAN; LIVER MICROSOME; MALE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; RAT; REGULATORY MECHANISM; TURNOVER TIME; YEAST;

ANIMALS; BINDING SITES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DOGS; HUMANS; MALE; MICROSOMES, LIVER; OXIDATION-REDUCTION; PEPTIDES, CYCLIC; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

MAMMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0035043963     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00364-3     Document Type: Article

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