Probing adenosine and P2 receptors: Design of novel purines and nonpurines as selective ligands

Drug Development Research

Volumn 52, Issue 1-2, 2001, Pages 178-186

  Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Adenosine receptors; G protein coupled receptors; Nucleoides; Nucleotides; Purines; Structure activity relationships; Template

Indexed keywords

1 [(PHOSPHATO)METHYL] 4 (2 CHLORO 6 METHYLAMINOPURIN 9 YL) BICYCLO[3.1.0]HEXANE 2 PHOSPHATE; 5 PROPYL 2 ETHYL 4 PROPYL 3 (ETHYLSULFANYLCARBONYL) 6 PHENYLPYRIDINE 5 CARBOXYLATE; 6 ETHYL 4 PROPYL 2 PHENYL 3 PYRIDINECARBOXYLIC ACID 5 THIOCARBOXYLIC ACID 5 ETHYL 3 PROPYL ESTER; 8 [4 [[(CARBOXY)METHYL]OXY]PHENYL] 1,3 DIPROPYLXANTHINE; ADENOSINE DERIVATIVE; ADENOSINE RECEPTOR; LIGAND; MRS 1760; MRS 1761; MRS 2279; N (4 CYANOPHENYL) 2 [4 (2,3,6,7 TETRAHYDRO 2,6 DIOXO 1,3 DIPROPYL 1H PURIN 8 YL)PHENOXY]ACETAMIDE; PURINE P2 RECEPTOR; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

BINDING AFFINITY; CONFERENCE PAPER; DRUG CONFORMATION; DRUG DESIGN; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; IC 50; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0035042635     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1113     Document Type: Conference Paper

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