Maintaining cell sensitivity to G-protein coupled receptor agonists: Neurotensin and the role of receptor gene activation

Journal of Neuroendocrinology

Volumn 13, Issue 5, 2001, Pages 473-479

  Souaze F ^a  

^a HÔPITAL SAINT ANTOINE   (France)

Author keywords

Cell sensitivity; G protein coupled receptor; Gene regulation; Neurotensin; Receptor internalization

Indexed keywords

G PROTEIN COUPLED RECEPTOR; HORMONE; NEUROTENSIN; NEUROTENSIN RECEPTOR;

ADAPTATION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL STIMULATION; CELL SURFACE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DESENSITIZATION; EXPOSURE; GENE ACTIVATION; HORMONE SENSITIVITY; HUMAN; HUMAN CELL; IN VIVO STUDY; INTERNALIZATION; MOUSE; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECEPTOR GENE; REGULATORY MECHANISM; STIMULUS; TIME; TURNOVER TIME;

ANIMALS; GENE EXPRESSION; GTP-BINDING PROTEINS; HUMANS; NEUROTENSIN; RECEPTORS, NEUROTENSIN;

EID: 0035040094     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.2001.00658.x     Document Type: Article

References (42)

1. Molecular mechanisms of G protein-coupled receptor desensitization and resensitization
2. Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes
3. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
4. Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors
5. Regulatory mechanisms that modulate signalling by G-protein-coupled receptors
6. Regulation and intracellular trafficking pathways of the endothelin receptors
7. Anatomy and mechanisms of neurotensin-dopamine interactions in the central nervous system
8. Neurotensin and neuroendocrine regulation
9. Pharmacology and biochemistry of neurotensin receptors
10. Neurotensin may function as a regulatory peptide in small cell lung cancer
11. Neurotensin stimulates growth of colon cancer
12. Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice
13. Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor
14. Neurotensin and neurotensin receptors
15. Mechanisms of regulation of neurotensin receptors
16. Thr-422 and Tyr-424 residues in the carboxyl terminus are critical for the internalization of the rat neurotensin receptor
17. Identification in the rat neurotensin receptor of amino-acid residues critical for the binding of neurotensin
18. Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization
19. Ligand-induced internalization of neurotensin in transfected COS-7 cells: Differential intracellular trafficking of ligand and receptor
20. JMV 449: A pseudopeptide analogue of neurotensin-(8-13) with highly potent and long-lasting hypothermic and analgesic effects in the mouse
21. Neurotensin agonist induces differential regulation of neurotensin receptor mRNA. Identification of distinct transcriptional and post-transcriptional mechanisms
22. Activation of receptor gene transcription is required to maintain cell sensitization after agonist exposure. Study on neurotensin receptor
23. Somatostatin-induced regulation of SST2A receptor expression and cell surface availability in central neurons: Role of receptor internalization
24. Receptor-mediated internalization is critical for the inhibition of the expression of growth hormone by somatostatin in the pituitary cell line AtT-20
25. Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
26. Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
27. Activation of mitogen-activated protein kinase couples neurotensin receptor stimulation to induction of the primary response gene Krox-24
28. Activation of the mitogen-activated protein kinase pathway by a Gq/11-coupled muscarinic receptor is independent of receptor internalization
29. Regulation of signal transduction by endocytosis
30. Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells
31. A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP
32. Paradoxical increase of 5-hydroxytryptamine2 receptors and 5-hydroxytryptamine2 receptor mRNA in cerebellar granule cells after persistent 5-hydroxytryptamine2 receptor stimulation
33. Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor 1
34. Corticotropin-releasing factor up-regulates its own receptor gene expression in corticotropic adenoma cells in vitro
35. Regulation of messenger ribonucleic acid for corticotropin releasing hormone receptor in the pituitary during stress
36. Regulation of corticotropin-releasing hormone receptor messenger ribonucleic acid in the rat brain and pituitary by glucocorticoids and stress
37. Differential effects of gonadotrophin-releasing hormone (GnRH) pulse frequency on gonadotrophin subunit and GnRH receptor messenger ribonucleic acid levels in vitro
38. Use of nonpeptide antagonists to explore the physiological roles of neurotensin. Focus on brain neurotensin/dopamine interactions
39. Neurotensin receptor down-regulation induced by dexamethasone and forskolin in rat hypothalamic cultures is mediated by endogenous neurotensin
40. Multiple neuropeptides stimulate clonal growth of small cell lung cancer: Effects of bradykinin, vasopressin, cholecystokinin, galanin, and neurotensin
41. Nonpeptide antagonists of neuropeptide receptors: Tools for research and therapy
42. Quantitative RT-PCR limits and accuracy