Dissociation of pulmonary vascular remodeling and right ventricular pressure in tissue angiotensin-converting enzyme-deficient mice under conditions of chronic alveolar hypoxia

American Journal of Respiratory and Critical Care Medicine

Volumn 163, Issue 5, 2001, Pages 1241-1245

  Van Suylen, Robert J ^a,b   Aartsen, Wendy M ^a   Smits, Jos F M ^a   Daemen, Mat J A P ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME DEFICIENCY; FEMALE; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HYPOXIA; LUNG ALVEOLUS HYPOVENTILATION; LUNG ARTERY PRESSURE; LUNG BLOOD VESSEL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

EID: 0035029744     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.163.5.2003144     Document Type: Article

References (26)

1. The small pulmonary arteries in emphysema
2. Rat pulmonary circulation after chronic hypoxia: Hemodynamic and structural features
3. Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization
4. Connective tissue production by vascular smooth muscle in development and disease
5. Active collagen synthesis by pulmonary arteries in human primary pulmonary hypertension
6. Regulation of pulmonary vascular wall cell growth: Developmental and site-specific heterogeneity
7. Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells
8. Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall
9. Vascular smooth muscle cell hypertrophy vs. hyperplasia: Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II
10. Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension
11. Role of angiotensin-converting enzyme and angiotensin II in development of hypoxic pulmonary hypertension
12. Inhibition of tissue angiotensin-converting enzyme with quinapril reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling
13. Prevention of pulmonary vascular changes of chronic alveolar hypoxia by inhibiting of angiotensin I-converting enzyme in the rat
14. Effects of SQ 14,225, an orally active inhibitor of angiotensin-converting enzyme, on hypoxic pulmonary hypertension and right ventricular hypertrophy in rats
15. Effects of cilazapril, a novel angiotensin converting enzyme inhibitor, on the structure of pulmonary arteries of rats exposed to chronic hypoxia
16. Pulmonary artery remodeling differs in hypoxia- and monocrotaline induced pulmonary hypertension
17. The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice
18. Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility
19. The alpha-smooth muscle actin-positive cells in healing human myocardial scars
20. Some statistical methods useful in circulation research
21. Angiotensin II stimulates proliferation of human pulmonary artery smooth muscle cells via the AT1 receptor
22. Chymase: Its pathophysiological roles and inhibitors
23. Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3
24. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study
25. Lack of sex-specific effects on the association between angiotensin-convertlng enzyme gene polymorphism and hypertension in Japanese
26. The DD genotype of the angiotensin converting enzyme gene is negatively associated with right ventricular hypertrophy in male patients with chronic obstructive pulmonary disease