Therapy of pulmonary hypertension: Targeting pathogenic mechanisms with selective treatment delivery

Critical Care Medicine

Volumn 29, Issue 5, 2001, Pages 1086-1087

  Rubin, L J ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Pulmonary hypertension; Therapy

Indexed keywords

PROSTACYCLIN DERIVATIVE; PROSTANOID; SILDENAFIL;

DRUG EFFICACY; DRUG TOLERABILITY; EDITORIAL; HUMAN; INTENSIVE CARE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SIDE EFFECT; VASCULAR ENDOTHELIUM;

EID: 0035025405     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200105000-00047     Document Type: Editorial

References (14)

1. Medical and surgical treatment options for pulmonary hypertension
2. An imbalance between the excretion of thromboxane and prostacyciin metabolites in pulmonary hypertension
3. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
4. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
5. Heterozygous germline mutations in BMPR2, encoding a TGF beta receptor, cause familial primary pulmonary hypertension. The International PPH Consortium
6. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
7. Aerosolized prostaeydin and iloprost in severe pulmonary hypertension
8. Continuous infusion of prostacyclin normalizes plasma markers of endothelial cell injury and platelet aggregation in primary pulmonary hypertension
9. Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension
10. Sildenafil in primary pulmonary hypertension Letter
11. Sildenafil as a selective pulmonary vasodilator in childhood primary pulmonary hypertension
12. Prolonged pulmonary vasodilator action of inhaled nitric oxide by Zaprinast in awake lambs
13. Sildenafil is a pulmonary vasodilator in awake lambs with acute pulmonary hypertension
14. Nebulized sildenafil is a selective pulmonary vasodilator in lambs with acute pulmonary hypertension