메뉴 건너뛰기




Volumn 16, Issue 3, 2001, Pages 197-202

Induction of mutant lymphocytes in cyclophosphamide- and chlorambucil-treated patients

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROPEROXYCYCLOPHOSPHAMIDE; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; TIOGUANINE;

EID: 0035023502     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/16.3.197     Document Type: Article
Times cited : (5)

References (45)
  • 1
    • 0028242718 scopus 로고
    • Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis
    • Allegretta, M., Albertini, R.J., Howell, M.D., Smith, L.R., Martin, R., McFarland, H.F., Sriram, S., Brostoff, S. and Steinman, L. (1994) Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis. J. Clin. Invest., 94, 105-109.
    • (1994) J. Clin. Invest. , vol.94 , pp. 105-109
    • Allegretta, M.1    Albertini, R.J.2    Howell, M.D.3    Smith, L.R.4    Martin, R.5    McFarland, H.F.6    Sriram, S.7    Brostoff, S.8    Steinman, L.9
  • 2
    • 0023926112 scopus 로고
    • Elevated frequencies of 6-thioguanine resistant lymphocytes in multiple sclerosis patients treated with cyclophosphamide: A prospective study
    • Ammenheuser, M.M., Ward, J.B., Jr, Whorton, E.B., Kilian, J.M. and Legator, M.S. (1988) Elevated frequencies of 6-thioguanine resistant lymphocytes in multiple sclerosis patients treated with cyclophosphamide: a prospective study. Mutat. Res., 204, 509-520.
    • (1988) Mutat. Res. , vol.204 , pp. 509-520
    • Ammenheuser, M.M.1    Ward J.B., Jr.2    Whorton, E.B.3    Kilian, J.M.4    Legator, M.S.5
  • 3
    • 0025858510 scopus 로고
    • Comparison of Hprt variant frequencies and chromosome aberration frequencies in lymphocytes from radiotherapy and chemotherapy patients: A prospective study
    • Ammenheuser, M.M., Au, W.W., Whorton, E.B., Jr, Belli, J.A. and Ward, J.B., Jr (1991) Comparison of Hprt variant frequencies and chromosome aberration frequencies in lymphocytes from radiotherapy and chemotherapy patients: a prospective study. Environ. Mol. Mutagen., 18, 126-135.
    • (1991) Environ. Mol. Mutagen. , vol.18 , pp. 126-135
    • Ammenheuser, M.M.1    Au, W.W.2    Whorton E.B., Jr.3    Belli, J.A.4    Ward J.B., Jr.5
  • 5
    • 0344837245 scopus 로고
    • Mutagenicity of cancer chemotherapeutic agents in the Salmonella/ microsome test
    • Benedict, W.F., Baker, M.S., Haroun, L., Choi, E. and Ames, B.N. (1977) Mutagenicity of cancer chemotherapeutic agents in the Salmonella/ microsome test. Cancer Res., 37, 2209-2213.
    • (1977) Cancer Res. , vol.37 , pp. 2209-2213
    • Benedict, W.F.1    Baker, M.S.2    Haroun, L.3    Choi, E.4    Ames, B.N.5
  • 6
    • 0022586863 scopus 로고
    • Cytogenetic effects of cyclophosphamide on human lymphocytes in vivo and in vitro
    • Bochkov, N.P., Filippova, T.V., Kuzin, S.M. and Stukalov, S.V. (1986) Cytogenetic effects of cyclophosphamide on human lymphocytes in vivo and in vitro. Mutat. Res., 159, 103-107.
    • (1986) Mutat. Res. , vol.159 , pp. 103-107
    • Bochkov, N.P.1    Filippova, T.V.2    Kuzin, S.M.3    Stukalov, S.V.4
  • 7
    • 0023718266 scopus 로고
    • Immunosuppression with high-dose i.v. cyclophosphamide and ACTH in progressive multiple sclerosis: Cumulative 6-year experience in 164 patients
    • Carter, J.L., Hafler, D.A., Dawson, D.M., Orav, J. and Weiner, H.L. (1988) Immunosuppression with high-dose i.v. cyclophosphamide and ACTH in progressive multiple sclerosis: cumulative 6-year experience in 164 patients. Neurology, 38 (Suppl.), 9-14.
    • (1988) Neurology , vol.38 , Issue.SUPPL. , pp. 9-14
    • Carter, J.L.1    Hafler, D.A.2    Dawson, D.M.3    Orav, J.4    Weiner, H.L.5
  • 8
    • 0021737050 scopus 로고
    • Mutation frequency in nurses and pharmacists working with cytotoxic drugs
    • Chrysostomou, A., Morley, A.A. and Seshadri, R. (1984) Mutation frequency in nurses and pharmacists working with cytotoxic drugs. Aust. NZ J. Med., 14, 831-834.
    • (1984) Aust. NZ J. Med. , vol.14 , pp. 831-834
    • Chrysostomou, A.1    Morley, A.A.2    Seshadri, R.3
  • 9
    • 0343584568 scopus 로고
    • Chromosome damage during nitrogen mustard therapy
    • Conen, P.E. and Lansky, G.S. (1961) Chromosome damage during nitrogen mustard therapy. Br. Med. J., ii, 1055-1057.
    • (1961) Br. Med. J. , vol.2 , pp. 1055-1057
    • Conen, P.E.1    Lansky, G.S.2
  • 11
    • 0027958297 scopus 로고
    • Assessment of clinical parameters associated with increased frequency of mutant T cells in patients with systemic lupus erythematosus
    • Dawisha, S.M., Gmelig-Meyling, F. and Steinberg, A.D. (1994) Assessment of clinical parameters associated with increased frequency of mutant T cells in patients with systemic lupus erythematosus. Arthrit. Rheum., 37, 270-277.
    • (1994) Arthrit. Rheum. , vol.37 , pp. 270-277
    • Dawisha, S.M.1    Gmelig-Meyling, F.2    Steinberg, A.D.3
  • 12
    • 0021858186 scopus 로고
    • Increased mutation frequency following treatment with cancer chemotherapy
    • Dempsey, J.L., Seshadri, R. and Morley, A.A. (1985) Increased mutation frequency following treatment with cancer chemotherapy. Cancer Res., 45, 2873-2877.
    • (1985) Cancer Res. , vol.45 , pp. 2873-2877
    • Dempsey, J.L.1    Seshadri, R.2    Morley, A.A.3
  • 14
    • 0018785705 scopus 로고
    • Mutagenicity in urine of nurses handling cytostatic drugs
    • Falck, K., Grohn, P., Sorsa, M., Vainio, H., Heinonen, E. and Holsti, L.R. (1979) Mutagenicity in urine of nurses handling cytostatic drugs. Lancet, 8128, 1250-1251.
    • (1979) Lancet , vol.8128 , pp. 1250-1251
    • Falck, K.1    Grohn, P.2    Sorsa, M.3    Vainio, H.4    Heinonen, E.5    Holsti, L.R.6
  • 15
    • 0025282802 scopus 로고
    • Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families
    • Gibbs, R.A., Nguyen, P.-N., Edwards, A., Civitello, A.B. and Caskey, C.T. (1990) Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families. Genomics, 7, 235-244.
    • (1990) Genomics , vol.7 , pp. 235-244
    • Gibbs, R.A.1    Nguyen, P.-N.2    Edwards, A.3    Civitello, A.B.4    Caskey, C.T.5
  • 16
    • 0021358397 scopus 로고
    • Mutagenicity of urine from nurses handling cytotoxic drugs
    • Gibson, J.F., Gompertz, D. and Hedworth-Whitty, R.B. (1984) Mutagenicity of urine from nurses handling cytotoxic drugs. Lancet, 8368, 100-101.
    • (1984) Lancet , vol.8368 , pp. 100-101
    • Gibson, J.F.1    Gompertz, D.2    Hedworth-Whitty, R.B.3
  • 17
    • 0032698083 scopus 로고    scopus 로고
    • Tissue-specific mutant frequencies and mutational spectra in cyclophosphamide-treated lacI transgenic mice
    • Gorelick, N.J., Andrews, J.L., de Boer, J.G., Young, R., Gibson, D.P. and Walker, V.A. (1999) Tissue-specific mutant frequencies and mutational spectra in cyclophosphamide-treated lacI transgenic mice. Environ. Mol. Mutagen., 34, 154-166.
    • (1999) Environ. Mol. Mutagen. , vol.34 , pp. 154-166
    • Gorelick, N.J.1    Andrews, J.L.2    De Boer, J.G.3    Young, R.4    Gibson, D.P.5    Walker, V.A.6
  • 18
    • 0032999653 scopus 로고    scopus 로고
    • Elimination of non-viable 6-thioguanine-sensitive T cells from viable T cells prior to PCR analysis
    • Grant, D.D., Glodstein, R., Karsh, J. and Birnboim, H.C. (1999) Elimination of non-viable 6-thioguanine-sensitive T cells from viable T cells prior to PCR analysis. J. Immunol. Methods, 225, 61-66.
    • (1999) J. Immunol. Methods , vol.225 , pp. 61-66
    • Grant, D.D.1    Glodstein, R.2    Karsh, J.3    Birnboim, H.C.4
  • 19
    • 0018654055 scopus 로고
    • Acute leukemia and immunosuppressive drug use
    • Grunwald, H.W. and Rosner, F. (1979) Acute leukemia and immunosuppressive drug use. Arch. Intern. Med., 139, 461-466.
    • (1979) Arch. Intern. Med. , vol.139 , pp. 461-466
    • Grunwald, H.W.1    Rosner, F.2
  • 20
    • 0025058133 scopus 로고
    • Increased frequency of 6-thioguanine-resistant lymphocytes in peripheral blood of workers employed in cyclophosphamide production
    • Huttner, E., Merger, U., Braun, R. and Schoneich, J. (1990) Increased frequency of 6-thioguanine-resistant lymphocytes in peripheral blood of workers employed in cyclophosphamide production. Mutat. Res., 243, 101-107.
    • (1990) Mutat. Res. , vol.243 , pp. 101-107
    • Huttner, E.1    Merger, U.2    Braun, R.3    Schoneich, J.4
  • 22
    • 0027741273 scopus 로고
    • Measurement of chromosomal aberration, sister chromatid exchange, hprt mutations, and DNA adducts in peripheral blood lymphocytes of human populations at increased risk for cancer
    • Jacobson-Kram, D. et al. (1993) Measurement of chromosomal aberration, sister chromatid exchange, hprt mutations, and DNA adducts in peripheral blood lymphocytes of human populations at increased risk for cancer. Environ. Health Perspect., 101 (Suppl. 3), 121-125.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.SUPPL. 3 , pp. 121-125
    • Jacobson-Kram, D.1
  • 23
    • 7344262505 scopus 로고    scopus 로고
    • p53 mutations in cyclophosphamide-associated bladder cancer
    • Khan, M.A. et al. (1998) p53 mutations in cyclophosphamide-associated bladder cancer. Cancer Epidemiol. Biomarkers Prevent., 7, 397-403.
    • (1998) Cancer Epidemiol. Biomarkers Prevent. , vol.7 , pp. 397-403
    • Khan, M.A.1
  • 24
    • 0025023493 scopus 로고
    • Leukemia following chemotherapy for ovarian cancer
    • Kaldor, J.M. et al. (1990) Leukemia following chemotherapy for ovarian cancer. New Engl. J. Med., 322, 1-6.
    • (1990) New Engl. J. Med. , vol.322 , pp. 1-6
    • Kaldor, J.M.1
  • 26
    • 0028053609 scopus 로고
    • Myelin basic protein peptide specificity and T-cell receptor gene usage of HPRT mutant T-cell clones in patients with multiple sclerosis
    • Lodge, P.A., Allegretta, M., Steinman, L. and Sriram, S (1994) Myelin basic protein peptide specificity and T-cell receptor gene usage of HPRT mutant T-cell clones in patients with multiple sclerosis. Ann. Neurol., 36, 734-740.
    • (1994) Ann. Neurol. , vol.36 , pp. 734-740
    • Lodge, P.A.1    Allegretta, M.2    Steinman, L.3    Sriram, S.4
  • 27
    • 0022392892 scopus 로고
    • Methods for study of mutations and mutagenesis in human lymphocytes
    • Morley, A.A., Trainor, K.J., Dempsey, J.L. and Seshadri, R.S. (1985) Methods for study of mutations and mutagenesis in human lymphocytes. Mutat. Res., 147, 363-367.
    • (1985) Mutat. Res. , vol.147 , pp. 363-367
    • Morley, A.A.1    Trainor, K.J.2    Dempsey, J.L.3    Seshadri, R.S.4
  • 28
    • 0022921845 scopus 로고
    • Thioguanine-resistant mutations induced by cytotoxic drugs in lymphocytes of patients with connective tissue diseases
    • Palmer, R.G., Smith-Burchnell, C.A., Dore, C.J. and Denman, A.M. (1986) Thioguanine-resistant mutations induced by cytotoxic drugs in lymphocytes of patients with connective tissue diseases. Br. J. Rheumatol., 25, 376-379.
    • (1986) Br. J. Rheumatol. , vol.25 , pp. 376-379
    • Palmer, R.G.1    Smith-Burchnell, C.A.2    Dore, C.J.3    Denman, A.M.4
  • 29
    • 0023917264 scopus 로고
    • Use of T cell cloning to detect in vivo mutations induced by T cell cloning to detect in vivo mutations induced by cyclophosphamide
    • Palmer, R.G., Smith-Burchnell, C.A., Pelton, B.K., Hylton, W. and Denman, A.M. (1988) Use of T cell cloning to detect in vivo mutations induced by T cell cloning to detect in vivo mutations induced by cyclophosphamide. Arthrit. Rheum., 31, 757-761.
    • (1988) Arthrit. Rheum. , vol.31 , pp. 757-761
    • Palmer, R.G.1    Smith-Burchnell, C.A.2    Pelton, B.K.3    Hylton, W.4    Denman, A.M.5
  • 30
    • 0023507384 scopus 로고
    • Clinical and pharmacologic effects of high dose single agent busulfan with autologous bone marrow support in the treatment of solid tumors
    • Peters, W.P. et al. (1987) Clinical and pharmacologic effects of high dose single agent busulfan with autologous bone marrow support in the treatment of solid tumors. Cancer Res., 47, 6402-6406.
    • (1987) Cancer Res. , vol.47 , pp. 6402-6406
    • Peters, W.P.1
  • 31
    • 0005942065 scopus 로고
    • DNA damage and mutagenesis induced by nitrogen mustards
    • Povirk, L.F. and Shuker, D.E. (1994) DNA damage and mutagenesis induced by nitrogen mustards. Mutat. Res., 318, 205-226.
    • (1994) Mutat. Res. , vol.318 , pp. 205-226
    • Povirk, L.F.1    Shuker, D.E.2
  • 32
    • 0030591653 scopus 로고    scopus 로고
    • Mutagenic damage to mammalian cells by therapeutic alkylating agents
    • Sanderson, B.J.S. and Shield, A.J. (1996) Mutagenic damage to mammalian cells by therapeutic alkylating agents. Mutat. Res., 355, 41-57.
    • (1996) Mutat. Res. , vol.355 , pp. 41-57
    • Sanderson, B.J.S.1    Shield, A.J.2
  • 33
    • 0025741096 scopus 로고
    • Dose-dependent cytotoxic and mutagenic effects of antineoplastic alkylating agents on human lymphoblastoid cells
    • Sanderson, B.J.S., Johnson, K.J. and Henner, W.D. (1991) Dose-dependent cytotoxic and mutagenic effects of antineoplastic alkylating agents on human lymphoblastoid cells. Environ. Mol. Mutagen., 17, 238-243.
    • (1991) Environ. Mol. Mutagen. , vol.17 , pp. 238-243
    • Sanderson, B.J.S.1    Johnson, K.J.2    Henner, W.D.3
  • 35
    • 0027399411 scopus 로고
    • The biology of alkylating-agent cellular injury
    • Shulman, L.N. (1993) The biology of alkylating-agent cellular injury. Hematol.-Oncol. Clin. N. Amer., 7, 325-335.
    • (1993) Hematol.-oncol. Clin. N. Amer. , vol.7 , pp. 325-335
    • Shulman, L.N.1
  • 36
    • 0030591666 scopus 로고    scopus 로고
    • Monitoring occupational exposure to cytostatic anticancer agents
    • Sorsa, M. and Anderson, D. (1996) Monitoring occupational exposure to cytostatic anticancer agents. Mutat. Res., 355, 253-261.
    • (1996) Mutat. Res. , vol.355 , pp. 253-261
    • Sorsa, M.1    Anderson, D.2
  • 37
    • 0028273924 scopus 로고
    • Longitudinal study of frequency of HPRT mutant T cells in patients with multiple sclerosis
    • Sriram, S. (1994) Longitudinal study of frequency of HPRT mutant T cells in patients with multiple sclerosis. Neurology, 44, 311-315.
    • (1994) Neurology , vol.44 , pp. 311-315
    • Sriram, S.1
  • 38
    • 0019504231 scopus 로고
    • Lack of mutagenic activity in urine from hospital pharmacists admixing antitumour drugs
    • Staiano, N., Gallelli, J.F., Adamson, R.H. and Thorgiersson, S.S. (1981) Lack of mutagenic activity in urine from hospital pharmacists admixing antitumour drugs. Lancet, 8220, 74-77.
    • (1981) Lancet , vol.8220 , pp. 74-77
    • Staiano, N.1    Gallelli, J.F.2    Adamson, R.H.3    Thorgiersson, S.S.4
  • 39
    • 0021282243 scopus 로고
    • Blood levels of alkylating metabolites of cyclophosphamide in the mouse after i.v. or oral administration
    • Struck, R. and Alberts, D.S. (1984) Blood levels of alkylating metabolites of cyclophosphamide in the mouse after i.v. or oral administration. Cancer Treatment Rep. 68, 765-770.
    • (1984) Cancer Treatment Rep. , vol.68 , pp. 765-770
    • Struck, R.1    Alberts, D.S.2
  • 40
    • 0027986943 scopus 로고
    • Risk of leukemia following treatment for non-Hodgkin's lymphoma
    • Travis, L.B. et al. (1994) Risk of leukemia following treatment for non-Hodgkin's lymphoma. J. Natl Cancer Inst., 86, 1450-1457.
    • (1994) J. Natl Cancer Inst. , vol.86 , pp. 1450-1457
    • Travis, L.B.1
  • 41
  • 43
    • 0021334121 scopus 로고
    • Monitoring exposure of nursing and pharmacy personnel to cytotoxic drugs: Urinary mutation assays and urinary platinum as markers of absorption
    • Venitt, S., Crofton-Sleigh, C., Hunt, J., Speechley, Y. and Briggs, K. (1984) Monitoring exposure of nursing and pharmacy personnel to cytotoxic drugs: urinary mutation assays and urinary platinum as markers of absorption. Lancet, 8368, 74-77.
    • (1984) Lancet , vol.8368 , pp. 74-77
    • Venitt, S.1    Crofton-Sleigh, C.2    Hunt, J.3    Speechley, Y.4    Briggs, K.5
  • 45
    • 0028032715 scopus 로고
    • Characteristic of hprt-mutant T cell lines in a lupus patient treated with cyclophosphamide
    • Wood, G.M., Dawisha, S. and Gourley, M. (1994) Characteristic of hprt-mutant T cell lines in a lupus patient treated with cyclophosphamide. Arthrit. Rheumat., 37, 1548-1552.
    • (1994) Arthrit. Rheumat. , vol.37 , pp. 1548-1552
    • Wood, G.M.1    Dawisha, S.2    Gourley, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.