Comparative effect of theophylline and aminophylline on theophylline blood concentrations and peripheral blood eosinophils in patients with asthma

Drugs under Experimental and Clinical Research

Volumn 27, Issue 2, 2001, Pages 83-88

  Kato, M ^a,b   Tatsuta, H ^a   Okada, K ^a   Sakamoto, K ^a   Morita, H ^a  

^a Kaizuka City Hospital   (Japan)

^b Kaizuka City Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHYLLINE; DIPROPHYLLINE; THEODRIP; THEOPHYLLINE;

ADOLESCENT; ADULT; AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CLINICAL TRIAL; DISEASE EXACERBATION; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; EOSINOPHIL; FEMALE; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; SIDE EFFECT;

ADULT; AGED; AGED, 80 AND OVER; AMINOPHYLLINE; ASTHMA; BRONCHODILATOR AGENTS; EOSINOPHILS; FEMALE; HUMANS; MALE; MIDDLE AGED; THEOPHYLLINE;

EID: 0035014407     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Kawai M., Kato M. Theophylline for the treatment of bronchial asthma: Present status. Methods Find. Exp. Clin. Pharmacol., 22(5), 309, 2000.
2. Mitenko P.A., Ogilvie R.I. Rational intravenous doses ot theophylline. N. Eng. J. Med., 289, 600, 1973.
3. Hendeles L., Jenkins J., Temple R. Revised FDA labeling guideline for theophylline oral dosage forms. Pharmacotherapy, 15, 409, 1995.
4. Hendeles L., Bighley L., Richardson R.H. Frequent toxicity from IV aminophylline infusions in critically ill patients. Drug Intel. Clin. Pharm., 11, 12, 1977.
5. Ogilvie R.I. Clinical pharmacokinetics of theophylline. Clin. Pharmacokinet., 3, 267, 1978.
6. Monks T.J., Smith R.L., Caldwell J.A. A metabolic and pharmacokinetics comparison of theophylline and aminophylline (theophylline ethylenediamine). J. Pharm. Pharmacol., 33, 93, 1981.
7. Reiss T.F., Chervinsky P., Dockhorn R.J., et al. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma: A multicenter, randomised, double-blind trial. Montelukast clinical research study group. Arch Intern. Med., 158, 1213, 1998.
8. Kraft M., Djukanovic R., Wilson S., et al. Alveolar tissue inflammation in asthma. Am. J. Respir. Crit. Care Med., 154, 1505, 1996.
9. Martin R.J. "Pathophysiology of Asthma: Inflammatory Response in Small Airways and Alveolar Area. Asthma and the Small Airways". American Thoracic Society, New York, 2000, pp. 1-6.
10. Hamid Q., Song Y., Kotsimbos T.C., et al. Inflammation of small airways in asthma. J. Allergy Clin. Immunol., 100, 44, 1997.
11. Barnes P.J., Pauwels R. Theophylline in the management of asthma: Time for reappraisal. Eur. Respir. J., 7, 579, 1994.
12. Lam A., Newhouse M.T. Management of asthma and chronic airflow limitation. Are methylxanthines obsolete? Chest. 98, 44, 1990.
13. Evans D.J., Taylor D.A., Zetterstrom O., et al. A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma. N. Engl. J. Med., 337, 1412, 1997
14. Barnes P.J. The role of theophylline in severe asthma. Eur. Respir. Rev., 6 88, 1996.
15. Kidney J., Dominguez M., Taylor P.M., et al. Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy. Am. J. Respir. Crit. Care Med., 151, 1907, 1995.
16. Magnussen H. Historical perspectives of theophylline treatment. Eur. Respir. Rev., 6, 70, 1996.
17. Kosmas E.N., Michaelides S.A., Polychronak A., et al. Theophylline induces a reduction in circulating interleukin-4 and interleukin-5 in atopic asthmatics. Eur. Respir. J., 13, 53, 1999.
18. Kojima J., Katoh H., Taniguchi T., et al. Usefulness and safety of theophylline injection form (Theodrio®) for the treatment of acute asthma. Methods Find. Exp. Clin. Pharmacol., 22(4), 247, 2000.
19. Kato M., Ueno, K. The treatment of asthma with a twice-a-day administration of sustained release theophylline (Uniphyl) [in Japanese]. Nikkyou, 59, 207, 2000.
20. Elias J.A., Levinson A.I. Hypersensitivity reactions to ethylenediamine in aminophylline. Am. Rev. Respir. Dis., 123, 550, 1981.
21. Ohta K., Nakagome K., Akiyama, K., et al. Aminophylline is effective on acute exacerbation of asthma in adults: Objective improvements in peak flow, spirogram, arterial blood gas measurements and lung sounds. Clin. Exp. Allergy., 26, 32, 1996.