Dexamethasone blocks antioestrogen- and oxidant-induced death of pituitary tumour cells

Journal of Endocrinology

Volumn 169, Issue 2, 2001, Pages 249-261

  Newton, C J ^a   Bilko, D ^a   Pappa, S ^a   Atkin, S L ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11 [4 [[5 [(4,4,5,5,5 PENTAFLUOROPENTYL)SULFONYL]PENTYL]OXY]PHENYL]ESTRADIOL; ADENOSINE TRIPHOSPHATE; ANTIESTROGEN; DEXAMETHASONE; ESTROGEN RECEPTOR; FULVESTRANT; GLUCOCORTICOID; GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOLYTIC ENZYME; HYDROGEN PEROXIDE; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE; STEROID RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIVISION; CELL GROWTH; CELL MEMBRANE CONDUCTANCE; CELL STRAIN GH3; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; CYTOSKELETON; DRUG INHIBITION; DRUG POTENTIATION; EXPOSURE; FLUORESCENCE MICROSCOPY; GLYCOLYSIS; HYPOPHYSIS TUMOR; MEMBRANE POTENTIAL; MEMBRANE VESICLE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY; TIME; TUMOR CELL; TUMOR CELL LINE;

ADENOSINE TRIPHOSPHATE; CELL DEATH; DEXAMETHASONE; ESTRADIOL; ESTROGEN RECEPTOR MODULATORS; ESTRONE; FLOW CYTOMETRY; FLUTAMIDE; GLUCOCORTICOIDS; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; GONANES; HUMANS; HYDROGEN PEROXIDE; MICROSCOPY, FLUORESCENCE; MIFEPRISTONE; PITUITARY NEOPLASMS; REACTIVE OXYGEN SPECIES; RECEPTOR CROSS-TALK; RECEPTORS, CELL SURFACE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035011949     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1690249     Document Type: Article

References (43)

1. Baker MS, Feigan J & Lowther DA 1989 The mechanism of chondrocyte hydrogen peroxide damage depletion ot intracellular ATP duo to suppression of glycolysis caused by oxidation of glyceraldehyde-3-phosphate dehydrogenase. Journal of Rheumatology 16 7-14.
2. Behl C, Lezoualc'h F, Trapp T, Widmenn M, Skutella T & Holsboer F 1997 Glucocorticoids enhance oxidative stress-induced cell death ot hippocampal neurones in vitro. Endocrinology 138 101-106.
3. Bigsby RM & Young PCM 1993 Progesterone and dexamethasone inhibition of uterine epithelial cell proliferation studies with antiprogesterone compounds in the neonatal mouse. Journal of Steroid Biochemistry and Molecular Biology 46 253-257.
4. Bunone G, Briand P-A, Miksicek RJ & Picard D 1996 Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO Journal 156 2174-2183.
5. Coulter CV, Kelso GF, Lin TK, Smith RAJ & Murphy MP 2000 Mitochondrially targeted antioxidants and thiol reagents. Free Radical Biology and Medicine 28 1547-1554.
6. L antagonize mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Research 57 62-67.
7. Eguchi Y, Shimizu S & Tsujimoto Y 1997 Intracellular ATP levels determine the fate by apoptosis or necrosis. Cancer Research 57 1835-1840.
8. Eguchi Y, Srinivasan A, Tomaselli KJ, Shigeomi S & Tsujimoto Y 1999 ATP-dependent steps in apoptotic signal transduction. Cancer Research 59 2174-2181.
9. Ekert P, MacLusky N, Luo P, Lehotay DC, Smith B, Post M & Tanswell AK 1997 Dexamethasone prevents apoptosis in a neonatal rat model of hypoxic-ischemic encephalopathy (HIE) by a reactive oxygen species-independent mechanism, Bram Reearch 747 9-17.
10. Feng Z, Marti A, Jehn B, Altermatt HJ, Chicaiza G & Jaggi R 1995 Glucocorticoid and progesterone inhibit involution and programmed cell death in the mouse mammary gland. Journal of Cell Biology 131 1095-1103.
11. Friend KE, Chiou YK, Lopes MBS, Laws ER, Hughes KM & Shupnik MA 1994 Estrogen receptor expression in human pituitary correlation with immunohistochemistry in normal tissue and immunohistochemistry and morphology in macroadenomas. Journal of Clinical Endocrinology and Metabolism 78 1497-1504.
12. Glass-Marmor L & Beitner R 1997 Detachment ot glycolytic enzymes from cytoskeleton of melanoma cells induced by calmodulin agonists. European Journal of Pharmacology 328 241-248.
13. Halder J, Ray M & Ray S 1993 Inhibition of glycolysis and mitochondnal respiration of ehrlich ascites carcinoma cells by methylglyoxal. International Journal of Cancer 54 443-449.
14. Harris RA, Hiles ID, Page MJ & O'Hare MJ 1995 The induction of apoptosis in human mammary luminal epithelial cells by expression of activated c-neu and its abrogation by glucocorticoids. British Journal of Cancer 72 386-392.
15. Haug E & Gautvik KM 1976 Effects ot sex steroids on prolactin secreting rat pituitary cells in culture. Endocrinology 99 1482-1487.
16. Hurd C & Moudgil VK 1998 Steroid hormone receptor families. In Handbook of Physiology, vol. 1, pp 383-411. Ed. M Conn. Oxford, UK: Oxford University Press.
17. 1-induced rat hepatoma cells by glucocorticoids. Carcinogenesis 19 1191-1202.
18. Katzenellenbogen BS, Bhakoo HS, Ferguson ER, Lan NC, Tatee T, Tsai TL & Katzenellenbogen JA 1979 Estrogen and antiestrogen action in reproductive tissues and tumours. Recent Progress in Hormone Research 35 259-300.
19. Keller JN, Guo Q, Holtsberg FW, Bruce-Keller AJ & Mattson MP 1998 Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 linked to perturbed calcium homeostasis and enhanced oxyradical production. Journal of Neuroscience 18 4439-4450.
20. Liles WC, Dale DC & Klebanotf SJ 1995 Glucocorticoids inhibit apoptosis of human neutrophils. Blood 86 3181-3188.
21. Maxwell SRJ & Lip GYH 1997 Reperfusion injury: a review of the pathophysiology, clinical manifestations and therapeutic options. International Journal of Cardiology 58 95-117.
22. Morita S, Matsuo K, Tsuruta M, Leng S, Yamashita S, Izumi M & Nagataki S 1990 Stimulatory effect of retinoic acid on GH gene expression: the interaction ot retinoic acid and tri-iodothyronine in rat pituitary cells. Journal of Endocrinology 125 251-256.
23. Newton CJ 1995 Estrogen receptor blockade by the pure antiestrogen. ZM 182780, induces death of pituitary tumour cells. Journal of Steroid Biochemistry and Molecular Biology 55 327-336.
24. Newton CJ, Arzt E & Stalla GK 1994a Involvement of the estrogen receptor in the growth response of pituitary tumour cells to interleukin-2. Biochemical and Biophysical Research Communications 205 1930-1937.
25. Newton CJ, Buric R, Trapp T, Brockmeier S. Pagotto U & Stalla GK 1994b The unliganded estrogen receptor (ER) transduces growth tactor signals. Journal of Steroid Biochemistry and Molecular Biology 48 481-486.
26. Newton CJ, Trapp T, Pagotto U, Renner U, Buric R & Stalla CK 1994c The oestrogen receptor modulates growth ot pituitary tumour cells in the absence of exogenous oestrogen. Journal of Molecular Endocrinology 12 303-312.
27. Newton CJ, Drummond N, Burgoyne CH, Speirs V, Stalla GK & Atkin SL 1999 Functional inactivation of the oestrogen receptor by the antiestrogen, ZM 182780, sensitises tumour cells to reactive oxygen species, Journal of Endocrinology 161 199-210.
28. Newton CJ, Eycott K, Green V & Atkin SL 2000 Response of estrogen receptor-containing tumour cells to pure antiestrogens and the calmodulin inhibitor, calmidzolium chloride. Journal of Steriod Biochemistry and Molecular Biology 73 29-38.
29. 3 pituitary cells. Endocrinology 106 600-605.
30. Reagan LP & McEwen BS 1997 Controversies surrounding glucocorticuid-mediated cell death in the hippocampus. Journal of Chemical Neuroanatomy 13 149-167.
31. Rist RJ & Naftalin RJ 1991 Dexamethasone inhibits the hexose monophosphate shunt in activated rat peritoneal macrophages by reducing hexokinase-mediated sugar uptake. Biochemical Journal 278 129-135.
32. Sahlin L 1995 Dexamethasone attenuates the estradiol-induced increase of IGF-I mRNA in the rat uterus. Journal of Steroid Biochemistry and Molecular Biology 55 9-15.
33. Sapolsky RM & Pulsinelli WA 1995 Glucocorticoids potentiate ischemic injury to neurones: therapeutic implications. Science 229 1397-1400.
34. Scheek RM & Slater EC 1982 Glyceradehyde-3-phosphate dehydrogenase from rabbit muscle. Methods in Enzymology 89 305-309.
35. Schwartzman RA & Cidlowski JA 1993 Apoptosis. The biochemistry and molecular biology of programmed cell death. Endocrine Reviews 14 133-151.
36. Schwartzman RA & Cidlowski JA 1994 Glucocorticoid-induced apoptosis of lymphoid cells. International Archives of Allergy and Immunology 105 347-354.
37. Sorrentino JM, Kirkland WL & Sirbasku DA 1976 Control of cell growth. I. Estrogen independent growth in vivo of a rat pituitary tumor cell line. Journal of the National Cancer Institute 56 1149-1154.
38. Tashjian AH, Yasumura L, Levine L, Sato GH & Parker ML 1968 Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. Endocrinology 82 342-352.
39. Van de Velde P, Nique F, Bouchoux F, Bremaud J, Hameau MC, Lucas D, Moratille C, Viet S, Philibert D & Teutsch G 1994 RU 58668, a new pure antiestrogen inducing a regression of human mammary carcinoma implanted in nude mice. Journal of Steroid Biochemistry and Molecular Biology 48 187-196.
40. Wakeling AE & Bowler J 1991 A potent specific pure antiestrogen with clinical potential. Cancer Research 51 3867-3873.
41. Wiklund J, Wertz N & Gorski J 1981 A comparison of estrogen effects on uterine and pituitary growth and prolactin synthesis in F344 and Holtzman rats. Endocrinology 109 1700-1707.
42. 2 pituitary tumor cells. Endocrinology 128 2761-2768.
43. Zhou-Li F, Albaladejo V, Joly-Pharaboz MO, Nicolas B & Andre J 1992 Antiestrogens prevent the stimulatory effects of 1-triiodothyronine on cell proliferation. Endocrinology 130 1145-1152.