Aptamers as reagents for high-throughput screening

BioTechniques

Volumn 30, Issue 5, 2001, Pages 1094-1110

  Green, Louis S ^a   Bell, Carol ^a   Janjic, Nebojsa ^a,b  

^a GILEAD SCIENCES   (United States)

^b Replidyne Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; DRUG PRODUCTS PLANTS; NUCLEIC ACIDS; PROTEINS;

APTAMERS;

DRUG THERAPY;

AGGLUTININ; APTAMER; NUCLEIC ACID; PLATELET DERIVED GROWTH FACTOR B;

ANIMAL CELL; ARTICLE; ASSAY; BINDING AFFINITY; CONTROLLED STUDY; GENETIC SCREENING; LIGAND BINDING; NONHUMAN; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN INTERACTION; PROTEIN TARGETING; VALIDATION PROCESS;

EID: 0035010462     PISSN: 07366205     EISSN: None     Source Type: Journal    
DOI: 10.2144/01305dd02     Document Type: Article

References (15)

1. Bridonneau, P., Y.-F. Chang, A.V.-B. Buvoli, D. O'Connell, and D. Parma. 1999. Site-directed selection of oligonucleotide antagonists by competitive elution. Antisense Nucleic Acid Drug Dev. 9:1-11.
2. Drolet, D.W., L. Moon-McDermott, and T.S. Romig. 1996. An enzyme-linked oligo-nucleotide assay. Nat. Biotechnol. 14:1021-1025.
3. Ellington, A. and J. Szostak. 1990. In vitro selection of RNA molecules that bind specific ligands. Nature 346:818-822.
4. Floege, J., T. Ostendorf, U. Janssen, M. Burg, H.H. Radeke, C. Vargeese, S.C. Gill, L.S. Green, and N. Janjic. 1999. Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers. Am. J. Pathol. 154:169-179.
5. Garrett, J.S., S.R. Coughlin, H.L. Niman, P.M. Tremble, G.M. Giels, and L.T. Williams. 1984. Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors. Proc. Natl. Acad. Sci. USA 81:7466-7470.
6. Gold, L., B. Polisky, O.C. Uhlenbeck, and M. Yarus. 1995. Diversity of oligonucleotide functions. Annu. Rev. Biochem. 64:763-797.
7. Goldstein, I.J. and R.D. Poretz. 1986. Isolation, physicochemical characterization, and carbohydrate-binding specificity of lectins, p. 33-247. In I.E Leiner, N. Sharon, and I.J. Goldstein (Eds.), The Lectins, Properties, Functions, and Applications in Biology and Medicine. Academic Press, Orlando, FL.
8. Green, L.S., D. Jellinek, R. Jenison, A. Östman, C.-H. Heldin, and N. Janjic. 1996. Inhibitory DNA ligands to platelet-derived growth factor B-chain. Biochemistry 35:14413-14424.
9. Hyde-DeRuyscher, R., L.A. Paige, D.J. Christensen, N. Hyde-DeRuyscher, A. Lim, Z.L. Fredericks, J. Kranz, P. Gallant et al. 2000. Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries. Chem. Biol. 7:17-25.
10. Osborne, S.E. and A.D. Ellington. 1997. Nucleic acid selection and the challenge of combinatorial chemistry. Chem. Rev. 97:349-370.
11. 2+ signaling and cell growth by polysulfonated azo dyes related to the antitumor agent suramin. Cancer Chemother. Pharmacol. 31:223-228.
12. Raines, E.W., D.F. Bowen-Pope, and R. Ross. 1990. Platelet-derived growth factor, p. 173-262. In M.B. Sporn and A.B. Roberts (Eds.), Handbook in Experimental Pharmacology. Peptide Growth Factors and Their Receptors, Vol. 1 Springer Verlag, Heidelberg.
13. 165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J. Biol. Chem. 273: 20556-20567.
14. Tuerk, C. and L. Gold. 1990. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249:505-510.
15. Varani, G. 1997. RNA-protein intermolecular recognition. Accounts Chem. Res. 30:189-195.