Arteriolar nitric oxide concentration is decreased during hyperglycemia-induced βII PKC activation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 2 49-2, 2001, Pages

  Bohlen, H Glenn ^a   Nase, Geoffrey P ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Arteriole; Protein kinase C

Indexed keywords

ACETYLCHOLINE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PROTEIN KINASE C; RUBOXISTAURIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIOLE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HYPERGLYCEMIA; HYPEROSMOLARITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

EID: 0035008602     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.2.h621     Document Type: Article

References (29)

1. Bohlen HG. Determinants of resting and passive intestinal vascular pressures in rat and rabbit. Am J Physiol Gastrointest Liver Physiol 253: G587-G595, 1987.
2. Bohlen HG. Mechanism of increased vessel wall nitric oxide concentrations during intestinal absorption. Am J Physiol Heart Circ Physiol 275: H542-H550, 1998.
3. Bohlen HG and Lash JM. Topical hyperglycemia rapidly suppresses EDRF-mediated vasodilation of normal rat arterioles. Am J Physiol Heart Circ Physiol 265: H219-H225, 1993.
4. Bohlen HG and Lash JM. Endothelial-dependent vasodilation is preserved in non-insulin-dependent Zucker fatty diabetic rats. Am J Physiol Heart Circ Physiol 268: H2366-H2374, 1995.
5. Bohlen HG and Unthank JL. Rat intestinal lymph osmolarity during glucose and oleic acid absorption. Am J Physiol Gastrointest Liver Physiol 257: G438-G446, 1989.
6. Buerk DG, Riva CE, and Cranstoun SD. Nitric oxide has a vasodilatory role in cat optic nerve head during flicker stimuli. Microvasc Res 52: 13-26, 1996.
7. Bursell S, Takagi C, Clermont AC, Takagi H, Mori F, Ishii H, and King GL-E. Specific retinal diacylglycerol and protein kinase C β-isoform modulation mimics abnormal retinal hemodynamics in diabetic rats. Invest Ophthalmol Vis Sci 38: 2711-2720, 1997.
8. Chakravarty U, Hayes RG, Stitt AW, McAuley E, and Archer DB. Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products. Diabetes 47: 945-952, 1998.
9. Falcone JC and Bohlen HG. EDRF from rat intestine and skeletal muscle venules causes dilation of arterioles. Am J Physiol Heart Circ Physiol 258: H1515-H1523, 1990.
10. Haller H, Drab M, and Luft FC. The role of hyperglycemia and hyperinsulinemia in the pathogenesis of diabetic angiopathy. Clin Nephrol 46: 246-255, 1996.
11. Hempel A, Maasch C, Heintze U, Lindschau C, Dietz R, Luft FC, and Haller H. High glucose concentrations increase endothelial cell permeability via activation of protein kinase C-α. Circ Res 81: 363-371, 1997.
12. Ishii DN. Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy. Brain Res 20: 47-67, 1995.
13. Ishii H, Jirousek MR, Koya D, Takagi C, Xia P, Clermont A, Bursell S-E, Kern TS, Ballas LM, Heath WF, Stramm LE, Feener EP, and King GL. Amelioration of vascular dysfunctions in diabetic rats by an oral PKC β inhibitor. Science 272: 728-731, 1996.
14. Jin J-S, and Bohlen HG. Non-insulin-dependent diabetes and hyperglycemia impair rat intestinal flow-mediated regulation. Am J Physiol Heart Circ Physiol 272: H728-H734, 1997.
15. King GL and Wakasaki H. Theoretical mechanisms by which hyperglycemia and insulin resistance could cause cardiovascular diseases in diabetes. Diabetes Care 22 Suppl 3: C31-C37, 1999.
16. Koya D and King GL. Protein kinase C activation and the development of diabetic complications. Diabetes 47: 859-866, 1998.
17. Laakso M, Edelman SV, Brechtel G, and Baron AD. Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM. Diabetes 41: 1076-1083, 1992.
18. Lash JM and Bohlen HG. Time and order dependent changes in functional and nitric oxide-mediated dilation during exercise training. J Appl Physiol 82: 460-468, 1997.
19. Lash JM, Nase GP, and Bohlen HG. Acute hyperglycemia depresses arteriolar NO formation in skeletal muscle. Am J Physiol Heart Circ Physiol 277: H1513-H1520, 1999.
20. Mayhan WG and Patel KP. Acute effects of glucose on reactivity of cerebral microcirculation: role of activation of protein kinase C. Am J Physiol Heart Circ Physiol 269: H1297-H1302, 1995.
21. Nakamura J, Kato K, Hamada Y, Nakayama M, Chaya S, Nakashima E, Naruse K, Kasuya Y, Mizubayashi R, Miwa K, Yasuda Y, Kamiya H, Ienaga K, Sakakibara F, Koh N, and Hotta N. A protein kinase C-β-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats. Diabetes 48: 2090-2095, 1999.
22. Pieper GM, Meier DA, and Hager SR. Endothelial dysfunction in a model of hyperglycemia and hyperinsulinemia. Am J Physiol Heart Circ Physiol 269: H845-H850, 1995.
23. Renaudin C, Michoud E, Rapin JR, Lagarde M, and Wiernsperger N. Hyperglycemia modifies the reaction of microvessels to insulin in rat skeletal muscle. Diabetologia 41: 26-33, 1998.
24. Shiba T, Inoguchi T, Sportsman JR, Heath WF, Bursell S, and King GL. Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation. Am J Physiol Endocrinol Metab 265: E783-E793, 1993.
25. Tesfamariam B. Free radicals in diabetic endothelial cell dysfunction. Free Radic Biol Med 16: 383-391, 1994.
26. Tesfamariam B and Cohen RA. Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am J Physiol Heart Circ Physiol 263: H321-H326, 1992.
27. Tesfamariam B and Halpern W. Endothelium-dependent and endothelium-independent vasodilation in resistance arteries from hypertensive rats. Hypertension 11: 440-444, 1988.
28. Williams SB, Goldfine AB, Timimi FK, Ting HH, Roddy M-A, Simonson DC, and Creager MA. Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo. Circulation 97: 1695-1701, 1998.
29. Wilson PWF, D'Agostino RB, Levy D, Belanger AM, Sibershatz H, and Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation 97: 1837-1847, 1998.