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Volumn 13, Issue 3, 2001, Pages 177-183

Combination therapy in rheumatoid arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; COLLAGEN TYPE 2; CORTICOSTEROID; CYCLOSPORIN A; HYDROXYCHLOROQUINE; METHOTREXATE; PREDNISOLONE; SALAZOSULFAPYRIDINE; TETRACOSACTIDE; TUMOR NECROSIS FACTOR ALPHA ANTAGONIST; UNCLASSIFIED DRUG;

EID: 0035002969     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002281-200105000-00005     Document Type: Review
Times cited : (33)

References (47)
  • 1
    • 0024673211 scopus 로고
    • Remodeling the pyramid-a concept whose time has come
    • 1 Wilske KR, Healey LA: Remodeling the pyramid-a concept whose time has come. J Rheumatol 1989, 16:565-567.
    • (1989) J Rheumatol , vol.16 , pp. 565-567
    • Wilske, K.R.1    Healey, L.A.2
  • 2
    • 0021212076 scopus 로고
    • Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years
    • 2 Pincus T, Callahan LF, Sale WG, et al.: Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years. Arthritis Rheum 1984, 27:864-872.
    • (1984) Arthritis Rheum , vol.27 , pp. 864-872
    • Pincus, T.1    Callahan, L.F.2    Sale, W.G.3
  • 3
    • 0023179033 scopus 로고
    • Long-term outcome of treating rheumatoid arthritis: Results after 20 years
    • 3 Scott DL, Symmons DP, Coulton BL, et al.: Long-term outcome of treating rheumatoid arthritis: results after 20 years. Lancet 1987, 1:1108-1111.
    • (1987) Lancet , vol.1 , pp. 1108-1111
    • Scott, D.L.1    Symmons, D.P.2    Coulton, B.L.3
  • 4
    • 0024795367 scopus 로고
    • Course and prognosis of early rheumatoid arthritis
    • 4 Rasker JJ, Cosh JA: Course and prognosis of early rheumatoid arthritis. Scand J Rheumatol 1989, (suppl) 79:45-56.
    • (1989) Scand J Rheumatol , vol.79 , Issue.SUPPL. , pp. 45-56
    • Rasker, J.J.1    Cosh, J.A.2
  • 5
    • 0026630114 scopus 로고
    • Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis: A prospective follow-up study of 147 patients
    • 5 van der Heijde DM, van Riel PL, van Leeuwen MA, et al.; Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis: a prospective follow-up study of 147 patients. Br J Rheumatol 1992, 31:519-525.
    • (1992) Br J Rheumatol , vol.31 , pp. 519-525
    • Van Der Heijde, D.M.1    Van Riel, P.L.2    Van Leeuwen, M.A.3
  • 6
    • 0025124368 scopus 로고
    • A toxicity index for comparison of side effects among different drugs
    • 6 Fries JF, Spitz PW, Williams CA, et al.: A toxicity index for comparison of side effects among different drugs. Arthritis Rheum 1990, 33:121-130.
    • (1990) Arthritis Rheum , vol.33 , pp. 121-130
    • Fries, J.F.1    Spitz, P.W.2    Williams, C.A.3
  • 7
    • 0026043128 scopus 로고
    • The relative toxicity of nonsteroidal antiinflammatory drugs
    • 7 Fries JF, Williams CA, Bloch DA: The relative toxicity of nonsteroidal antiinflammatory drugs. Arthritis Rheum 1991, 34:1353-1360.
    • (1991) Arthritis Rheum , vol.34 , pp. 1353-1360
    • Fries, J.F.1    Williams, C.A.2    Bloch, D.A.3
  • 8
    • 0027415115 scopus 로고
    • The relative toxicity of disease-modifying antirheumatic drugs
    • 8 Fries JF, Williams CA, Ramey D, et al.: The relative toxicity of disease-modifying antirheumatic drugs. Arthritis Rheum 1993, 36:297-306.
    • (1993) Arthritis Rheum , vol.36 , pp. 297-306
    • Fries, J.F.1    Williams, C.A.2    Ramey, D.3
  • 9
    • 0025308298 scopus 로고
    • Reevaluating the therapeutic approach to rheumatoid arthritis: The "sawtooth" strategy
    • 9 Fries JF: Reevaluating the therapeutic approach to rheumatoid arthritis: the "sawtooth" strategy. J Rheumatol 1990, 22 (suppl):12-15.
    • (1990) J Rheumatol , vol.22 , Issue.SUPPL. , pp. 12-15
    • Fries, J.F.1
  • 10
    • 0032833160 scopus 로고    scopus 로고
    • Utility of disease modifying antirheumatic drugs in "sawtooth" strategy: A prospective study of early rheumatoid arthritis patients up to 15 years
    • 10 Sokka T, Hannonen P: Utility of disease modifying antirheumatic drugs in "sawtooth" strategy: a prospective study of early rheumatoid arthritis patients up to 15 years. Ann Rheum Dis 1999, 58:618-622.
    • (1999) Ann Rheum Dis , vol.58 , pp. 618-622
    • Sokka, T.1    Hannonen, P.2
  • 11
    • 0033974483 scopus 로고    scopus 로고
    • Disease-modifying anti-rheumatic drug use according to the "sawtooth" treatment strategy improves the functional outcome in rheumatoid arthritis: Results of a long-term follow-up study with review of the literature
    • 11 Sokka T, Möttönen T, Hannonen P: Disease-modifying anti-rheumatic drug use according to the "sawtooth" treatment strategy improves the functional outcome in rheumatoid arthritis: results of a long-term follow-up study with review of the literature. Rheumatology (Oxford) 2000, 39:34-42.
    • (2000) Rheumatology (Oxford) , vol.39 , pp. 34-42
    • Sokka, T.1    Möttönen, T.2    Hannonen, P.3
  • 13
    • 73649183187 scopus 로고
    • Combined therapy of rheumatoid arthritis with gold and chloroquine, I evaluation of the therapeutic effect
    • 13 Siever K, Hurri L: Combined therapy of rheumatoid arthritis with gold and chloroquine, I Evaluation of the therapeutic effect. Acta Rheum Scand 1963, 9:948-955.
    • (1963) Acta Rheum Scand , vol.9 , pp. 948-955
    • Siever, K.1    Hurri, L.2
  • 14
    • 0027946325 scopus 로고
    • The efficacy and toxicity of combination therapy in rheumatoid arthritis; a meta-analysis
    • 14 Felson DT, Anderson JJ, Meenan RF: The efficacy and toxicity of combination therapy in rheumatoid arthritis; a meta-analysis. Arthritis Rheum 1994, 37:1487-1491.
    • (1994) Arthritis Rheum , vol.37 , pp. 1487-1491
    • Felson, D.T.1    Anderson, J.J.2    Meenan, R.F.3
  • 15
    • 0031949858 scopus 로고    scopus 로고
    • Combination therapy in rheumatoid arthritis: Updated systematic review
    • 15 Verhoeven AC, Boers M, Tugwell P: Combination therapy in rheumatoid arthritis: updated systematic review. Br J Rheumatol 1998, 37:612-619.
    • (1998) Br J Rheumatol , vol.37 , pp. 612-619
    • Verhoeven, A.C.1    Boers, M.2    Tugwell, P.3
  • 16
    • 0034082253 scopus 로고    scopus 로고
    • Factors predicting response to treatment in rheumatoid arthritis: The importance of disease duration
    • 16 Anderson JJ, Wells G, Verhoeven AC, et al.: Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration. Arthritis Rheum 2000, 43:22-29.
    • (2000) Arthritis Rheum , vol.43 , pp. 22-29
    • Anderson, J.J.1    Wells, G.2    Verhoeven, A.C.3
  • 17
    • 0029869174 scopus 로고    scopus 로고
    • The effectiveness of early treatment with "second-line" antirheumatic drugs: A randomized, controlled trial
    • 17 van der Heide A, Jacobs JW, Bijlsma JW, et al.: The effectiveness of early treatment with "second-line" antirheumatic drugs: a randomized, controlled trial. Ann Intern Med 1996, 124:699-707.
    • (1996) Ann Intern Med , vol.124 , pp. 699-707
    • Van Der Heide, A.1    Jacobs, J.W.2    Bijlsma, J.W.3
  • 18
    • 0034101655 scopus 로고    scopus 로고
    • Consequences of delayed therapy with second-line agents in rheumatoid arthritis: A 3 year follow-up on the hydroxychloroquine in early rheumatoid arthritis (HERA) study
    • 18 Tsakonas E, Fitzgerald AA, Fitzcharles MA, et al.: Consequences of delayed therapy with second-line agents in rheumatoid arthritis: a 3 year follow-up on the hydroxychloroquine in early rheumatoid arthritis (HERA) study. J Rheumatol 2000, 27:623-629. This study demonstrates the importance of early treatment with DMARDs.
    • (2000) J Rheumatol , vol.27 , pp. 623-629
    • Tsakonas, E.1    Fitzgerald, A.A.2    Fitzcharles, M.A.3
  • 19
    • 0032957015 scopus 로고    scopus 로고
    • Combination therapy in early rheumatoid arthritis: A randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components
    • 19 Dougados M, Combe B, Cantagrel A, et al.: Combination therapy in early rheumatoid arthritis: a randomised, controlled, double blind 52 week clinical trial of sulphasalazine and methotrexate compared with the single components. Ann Rheum Dis 1999, 58:220-225.
    • (1999) Ann Rheum Dis , vol.58 , pp. 220-225
    • Dougados, M.1    Combe, B.2    Cantagrel, A.3
  • 20
    • 0030696346 scopus 로고    scopus 로고
    • Combination of sulphasalazine and methotrexate versus the single components in early rheumatoid arthritis: A randomized, controlled, double-blind, 52 week clinical trial
    • 20 Haagsma CJ, van Riel PL, de Jong AJ, et al.: Combination of sulphasalazine and methotrexate versus the single components in early rheumatoid arthritis: a randomized, controlled, double-blind, 52 week clinical trial. Br J Rheumatol 1997, 36:1082-1088.
    • (1997) Br J Rheumatol , vol.36 , pp. 1082-1088
    • Haagsma, C.J.1    Van Riel, P.L.2    De Jong, A.J.3
  • 21
    • 0033535754 scopus 로고    scopus 로고
    • Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: A randomised trial. FIN-RACo trial group
    • 21 Möttönen T, Hannonen P, Leirisalo-Repo M, et al.: Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial. FIN-RACo trial group. Lancet 1999, 353:1568-1573. In this study, the beneficial efficacy of the combination of methotrexate, sulfasalazine, hydroxychloroquine, and prednisolone above monotherapy in patients with early RA is demonstrated.
    • (1999) Lancet , vol.353 , pp. 1568-1573
    • Möttönen, T.1    Hannonen, P.2    Leirisalo-Repo, M.3
  • 22
    • 0344286554 scopus 로고    scopus 로고
    • Combination therapy versus monotherapy for the treatment of patients with rheumatoid arthritis
    • 22 Calgüneri M, Pay S, Caliskaner Z, et al.: Combination therapy versus monotherapy for the treatment of patients with rheumatoid arthritis. C in Exp Rheumatol 1999, 17:699-704.
    • (1999) Clin Exp Rheumatol , vol.17 , pp. 699-704
    • Calgüneri, M.1    Pay, S.2    Caliskaner, Z.3
  • 23
    • 0031791048 scopus 로고    scopus 로고
    • Cyclosporine A in the treatment of early rheumatoid arthritis. A prospective, randomized 24-month study
    • 23 Drosos AA, Voulgari PV, Papadopoulos IA, et al.: Cyclosporine A in the treatment of early rheumatoid arthritis. A prospective, randomized 24-month study. Clin Exp Rheumatol 1998, 16:695-701.
    • (1998) Clin Exp Rheumatol , vol.16 , pp. 695-701
    • Drosos, A.A.1    Voulgari, P.V.2    Papadopoulos, I.A.3
  • 24
    • 0034070295 scopus 로고    scopus 로고
    • Influence of cyclosporin A on radiologic progression in early rheumatoid arthritis patients: A 42-month prospective study
    • 24 Drosos AA, Voulgari PV, Katsaraki A, et al.: Influence of cyclosporin A on radiologic progression in early rheumatoid arthritis patients: a 42-month prospective study. Rheumatol Int 2000, 19:113-118.
    • (2000) Rheumatol Int , vol.19 , pp. 113-118
    • Drosos, A.A.1    Voulgari, P.V.2    Katsaraki, A.3
  • 25
    • 0033869333 scopus 로고    scopus 로고
    • Treatment of poor-prognosis early rheumatoid arthritis: A randomized study of treatment with methotrexate, cyclosporin A, and intraarticular corticosteroids compared with sulfasalazine alone
    • 25 Proudman SM, Conaghan PG, Richardson C, et al.: Treatment of poor-prognosis early rheumatoid arthritis: a randomized study of treatment with methotrexate, cyclosporin A, and intraarticular corticosteroids compared with sulfasalazine alone. Arthritis Rheum 2000, 43:1809-1819.
    • (2000) Arthritis Rheum , vol.43 , pp. 1809-1819
    • Proudman, S.M.1    Conaghan, P.G.2    Richardson, C.3
  • 26
    • 0032931201 scopus 로고    scopus 로고
    • Efficacy and safety of a combination therapy of methotrexate, chloroquine and cyclophosphamide in patients with refractory rheumatoid arthritis: Results of an observational study with matched-pair analysis
    • 26 Keyszer G, Keysser C, Keysser M: Efficacy and safety of a combination therapy of methotrexate, chloroquine and cyclophosphamide in patients with refractory rheumatoid arthritis: results of an observational study with matched-pair analysis. Clin Rheumatol 1999, 18:145-151.
    • (1999) Clin Rheumatol , vol.18 , pp. 145-151
    • Keyszer, G.1    Keysser, C.2    Keysser, M.3
  • 27
    • 0032745849 scopus 로고    scopus 로고
    • Combination DMARD treatment with parenteral gold and methotrexate
    • 27 Rau R: Combination DMARD treatment with parenteral gold and methotrexate. Clin Exp Rheumatol 1999, 17:S83-90.
    • (1999) Clin Exp Rheumatol , vol.17
    • Rau, R.1
  • 28
    • 0033611472 scopus 로고    scopus 로고
    • A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
    • 28 Weinblatt ME, Kremer JM, Bankhurst AD, et al.: A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 1999, 340:253-259. This study shows that the combination of a TNF-α blocking agent and methotrexate offers more rapid and greater clinical improvement compared with methotrexate monotherapy in patients with long-term RA.
    • (1999) N Engl J Med , vol.340 , pp. 253-259
    • Weinblatt, M.E.1    Kremer, J.M.2    Bankhurst, A.D.3
  • 29
    • 0002010742 scopus 로고    scopus 로고
    • Etanercept (Enbrel) in addition to methotrexate (MTX) in rheumatoid arthritis (RA): Long-term observations
    • 29 Kremer JM, Weinblatt ME, Fleischman RM, et al.: Etanercept (Enbrel) in addition to methotrexate (MTX) in rheumatoid arthritis (RA): long-term observations [abstract]. Arthritis Rheum 2000, 43:S270.
    • (2000) Arthritis Rheum , vol.43
    • Kremer, J.M.1    Weinblatt, M.E.2    Fleischman, R.M.3
  • 30
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis
    • 30 Lipsky PE, van der Heijde DM, St Clair EW, et al.: Infliximab and methotrexate in the treatment of rheumatoid arthritis. N Engl J Med 2000, 343:1594-1602. The sustained clinical efficacy as well as the sustained prevention of erosions of the combination of methotrexate and a TNF-α blocking agent in patients with chronic RA is demonstrated.
    • (2000) N Engl J Med , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    Van Der Heijde, D.M.2    St Clair, E.W.3
  • 31
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric anti-tumor necrosis factor alpha-monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised phase III trial
    • ATTRACT study group
    • 31 Maini R, St Clair EW, Breedveld F, et al.: Infliximab (chimeric anti-tumor necrosis factor alpha-monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 1999, 354:1932-1939. This study shows the superiority of the combination of a TNF-α blocking agent and methotrexate above methotrexate alone in patients with chronic RA during the first 30 weeks of treatment.
    • (1999) Lancet , vol.354 , pp. 1932-1939
    • Maini, R.1    St Clair, E.W.2    Breedveld, F.3
  • 32
    • 0000609675 scopus 로고    scopus 로고
    • 102-week clinical & radiologic results from the ATTRACT trial: A 2 year, randomized, controlled, phase 3 trial of infliximab (remicade) in patients with active RA despite MTX
    • 32 Lipsky P, van der Heijde D, St Clair W, et al.: 102-week clinical & radiologic results from the ATTRACT trial: a 2 year, randomized, controlled, phase 3 trial of infliximab (Remicade) in patients with active RA despite MTX [abstract]. Arthritis Rheum 2000, 43:S269.
    • (2000) Arthritis Rheum , vol.43
    • Lipsky, P.1    Van Der Heijde, D.2    St Clair, W.3
  • 33
    • 0033000532 scopus 로고    scopus 로고
    • Lack of efficacy of oral bovine type II collagen added to existing therapy in rheumatoid arthritis
    • 33 McKown KM, Carbone LD, Kaplan SB, et al.: Lack of efficacy of oral bovine type II collagen added to existing therapy in rheumatoid arthritis. Arthritis Rheum 1999, 42:1204-1208.
    • (1999) Arthritis Rheum , vol.42 , pp. 1204-1208
    • McKown, K.M.1    Carbone, L.D.2    Kaplan, S.B.3
  • 34
    • 0032751786 scopus 로고    scopus 로고
    • Inpatient treatment of rheumatoid arthritis with synacthen depot: A double blind placebo controlled trial with 6 month follow-up
    • 34 Taylor WJ, Rajapakse CN, Harris KA, et al.: Inpatient treatment of rheumatoid arthritis with synacthen depot: a double blind placebo controlled trial with 6 month follow-up. J Rheumatol 1999, 26:2544-2550.
    • (1999) J Rheumatol , vol.26 , pp. 2544-2550
    • Taylor, W.J.1    Rajapakse, C.N.2    Harris, K.A.3
  • 35
    • 0032808493 scopus 로고    scopus 로고
    • Early referral, diagnosis, and treatment of rheumatoid arthritis: Evidence for changing medical practice
    • 35 Irvine S, Munro R, Porter D: Early referral, diagnosis, and treatment of rheumatoid arthritis: evidence for changing medical practice. Ann Rheum Dis 1999, 58:510-513.
    • (1999) Ann Rheum Dis , vol.58 , pp. 510-513
    • Irvine, S.1    Munro, R.2    Porter, D.3
  • 36
    • 0002184573 scopus 로고    scopus 로고
    • Combination DMARD therapy for rheumatoid arthritis: Apparent universal acceptance
    • 36 O'Dell J: Combination DMARD therapy for rheumatoid arthritis: apparent universal acceptance [abstract]. Arthritis Rheum 1997, 40:S50.
    • (1997) Arthritis Rheum , vol.40
    • O'Dell, J.1
  • 37
    • 0032692182 scopus 로고    scopus 로고
    • Management of patients with newly diagnosed rheumatoid arthritis
    • 37 Emery P, Marzo H, Proudman S: Management of patients with newly diagnosed rheumatoid arthritis. Rheumatology (Oxford) 1999, 38 (suppl 2):27-31.
    • (1999) Rheumatology (Oxford) , vol.38 , Issue.SUPPL. 2 , pp. 27-31
    • Emery, P.1    Marzo, H.2    Proudman, S.3
  • 38
    • 0034079894 scopus 로고    scopus 로고
    • Current treatment paradigms in rheumatoid arthritis
    • 38 Fries JF: Current treatment paradigms in rheumatoid arthritis. Rheumatology (Oxford) 2000, 39 (suppl 1):30-35.
    • (2000) Rheumatology (Oxford) , vol.39 , Issue.SUPPL. 1 , pp. 30-35
    • Fries, J.F.1
  • 39
    • 0032720050 scopus 로고    scopus 로고
    • Rheumatoid arthritis: New developments in the use of existing therapies
    • 39 O'Dell JR, Scott DL: Rheumatoid arthritis: new developments in the use of existing therapies. Rheumatology (Oxford) 1999, 38 (suppl 2):24-26.
    • (1999) Rheumatology (Oxford) , vol.38 , Issue.SUPPL. 2 , pp. 24-26
    • O'Dell, J.R.1    Scott, D.L.2
  • 40
    • 0032760136 scopus 로고    scopus 로고
    • Combination therapy with multiple disease-modifying antirheumatic drugs in rheumatoid arthritis: A preventive strategy
    • 40 Pincus T, O'Dell JR, Kremer JM: Combination therapy with multiple disease-modifying antirheumatic drugs in rheumatoid arthritis: a preventive strategy. Ann Intern Med 1999, 131:768-774.
    • (1999) Ann Intern Med , vol.131 , pp. 768-774
    • Pincus, T.1    O'Dell, J.R.2    Kremer, J.M.3
  • 41
    • 0034091447 scopus 로고    scopus 로고
    • New and future drug therapies for rheumatoid arthritis
    • 41 Simon LS, Yocum D: New and future drug therapies for rheumatoid arthritis. Rheumatology (Oxford) 2000, 39 (suppl 1):36-42.
    • (2000) Rheumatology (Oxford) , vol.39 , Issue.SUPPL. 1 , pp. 36-42
    • Simon, L.S.1    Yocum, D.2
  • 42
    • 0032692512 scopus 로고    scopus 로고
    • The role of current strategies in the future treatment of rheumatoid arthritis
    • 42 Weinblatt ME: The role of current strategies in the future treatment of rheumatoid arthritis. Rheumatology (Oxford) 1999, 38 (suppl 2):19-23.
    • (1999) Rheumatology (Oxford) , vol.38 , Issue.SUPPL. 2 , pp. 19-23
    • Weinblatt, M.E.1
  • 43
    • 0034662099 scopus 로고    scopus 로고
    • Aggressive strategies for treating aggressive rheumatoid arthritis: Has the case been proven?
    • 43 Furst DE: Aggressive strategies for treating aggressive rheumatoid arthritis: has the case been proven? Lancet 2000, 356:183-184.
    • (2000) Lancet , vol.356 , pp. 183-184
    • Furst, D.E.1
  • 44
    • 9244247260 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and nydroxychloroquine, or a combination of all three medications
    • 44 O'Dell JR, Haire CE, Erikson N, et al.: Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and nydroxychloroquine, or a combination of all three medications. N Engl J Med 1996, 334:1287-1291.
    • (1996) N Engl J Med , vol.334 , pp. 1287-1291
    • O'Dell, J.R.1    Haire, C.E.2    Erikson, N.3
  • 45
    • 0029022389 scopus 로고
    • Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis. The methotrexate-cyclosporine combination study group
    • 45 Tugwell P, Pincus T, Yocum D, et al.: Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis. The Methotrexate-Cyclosporine Combination Study Group. N Engl J Med 1995, 333:137-141.
    • (1995) N Engl J Med , vol.333 , pp. 137-141
    • Tugwell, P.1    Pincus, T.2    Yocum, D.3
  • 46
    • 0030751946 scopus 로고    scopus 로고
    • Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis
    • erratum appears in Lancet 1998,351:220
    • 46 Boers M, Verhoeven AC, Markusse HM, et al.: Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis [erratum appears in Lancet 1998,351:220]. Lancet 1997, 350:309-318.
    • (1997) Lancet , vol.350 , pp. 309-318
    • Boers, M.1    Verhoeven, A.C.2    Markusse, H.M.3
  • 47
    • 4243589837 scopus 로고    scopus 로고
    • Legacy of COBRA combination therapy: Gain in damage control is probably permanent
    • 47 Landewe RBM, Boers M, Verhoeven AC: Legacy of COBRA combination therapy: gain in damage control is probably permanent [abstract]. Arthritis Rheum 2000, 43:S382.
    • (2000) Arthritis Rheum , vol.43
    • Landewe, R.B.M.1    Boers, M.2    Verhoeven, A.C.3


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