Activities of cholic acid-derived antimicrobial agents against multidrug-resistant bacteria

Journal of Antimicrobial Chemotherapy

Volumn 47, Issue 5, 2001, Pages 671-674

  Schmidt, Erica J ^a   Boswell, J Scott ^a   Walsh, Joshua P ^a   Schellenberg, Matthew M ^a   Winter, Timothy W ^a   Li, Chunhong ^b   Allman, Glenn W ^a   Savage, Paul B ^b  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

^b Brigham Young University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; BETA LACTAM; CATION; CHOLIC ACID DERIVATIVE; CLINDAMYCIN; ERYTHROMYCIN; POLYPEPTIDE ANTIBIOTIC AGENT;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; BACTERIUM; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SENSITIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HYDROPHOBICITY; MULTIDRUG RESISTANCE; NONHUMAN; OUTER MEMBRANE; PROKARYOTE;

EID: 0035001225     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/47.5.671     Document Type: Article

References (7)

1. Hancock, R. E. W., Falla, T. & Brown, M. (1995). Cationic bactericidal peptides. Advances in Microbial Physiology 37, 135-75.
2. Shai, Y. (1999). Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochimica et Biophysica Acta 1462, 55-70.
3. Li, C., Lewis, M. R., Gilbert, A. B., Noel, M. D., Scoville, D. H., Allman, G. W. et al. (1999). Antimicrobial activities of amine- and guanidine-functionalized cholic acid derivatives. Antimicrobial Agents and Chemotherapy 43, 1347-9.
4. Li, C., Budge, L. P., Driscoll, C. D., Willardson, B. M., Allman, G. W. & Savage, P. B. (1999). Incremental conversion of outer-membrane permeabilizers into potent antibiotics for gram-negative bacteria. Journal of the American Chemical Society 121, 931-40.
5. National Committee for Clinical Laboratory Standards. (1997). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically - Fourth Edition: Approved Standard M7-A4. NCCLS, Villanova, PA.
6. Eliopoulos, G. M. & Moellering, R. C. (1991). In Antibiotics in Laboratory Medicine, (Lorian, V., Ed.), pp. 432-92. Williams and Wilkins Co., Baltimore, MD.
7. Matsuzaki, K., Sugishita, K., Fukii, N. & Miyajima, K. (1995). Molecular basis for membrane selectivity of an antimicrobial peptide, magainin 2. Biochemistry 34, 3423-9.