Both cerebral GABAA receptors and spinal GABAA receptors modulate the capacity of isoflurane to produce immobility

Anesthesia and Analgesia

Volumn 92, Issue 6, 2001, Pages 1585-1589

  Zhang, Yi ^a   Stabernack, Caroline ^a   Sonner, James ^a,b   Dutton, Robert ^a   Eger II, Edmond I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ISOFLURANE; PICROTOXIN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN VENTRICLE; DOSE RESPONSE; DRUG RECEPTOR BINDING; IMMOBILIZATION; MALE; MINIMUM LUNG ALVEOLUS CONCENTRATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

EID: 0035001192     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200106000-00047     Document Type: Article

References (14)

1. A nor strychnine-sensitive glycine receptors are the sole mediators of MAC for isoflurane
2. A receptor channel-lining residues probed in cysteine mutants
3. A and glycine receptors
4. The glycine receptor
5. Exaggerated anesthetic requirements in the preferentially anesthetized brain
6. Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia?
7. Anesthetic potency (MAC) is independent of forebrain structures in the rat
8. Anesthetic potency is not altered after hypothermic spinal cord transection in rats
9. The role of the GABAA receptor/chloride channel complex in anesthesia
10. Chronic catheterization of the spinal subarachnoid space
11. Picrotoxin produces a "central" pain-like syndrome when microinjected into the somato-motor cortex of the rat
12. A receptors
13. Does intravenous administration of GABA(A) receptor antagonists induce both descending antinociception and touch evoked allodynia?
14. Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice