Neither GABAA nor strychnine-sensitive glycine receptors are the sole mediators of MAC for isoflurane

Anesthesia and Analgesia

Volumn 92, Issue 1, 2001, Pages 123-127

  Zhang, Yi ^a   Wu, Susan ^a   Eger II, Edmond I ^a   Sonner, James M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; AMPA RECEPTOR; GLYCINE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PICROTOXIN; STRYCHNINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; GABAERGIC SYSTEM; IMMOBILIZATION; INHALATION ANESTHESIA; MALE; MINIMUM LUNG ALVEOLUS CONCENTRATION; NEUROMODULATION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

EID: 0035165456     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200101000-00024     Document Type: Article

References (19)

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3. Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes
4. Ethanol, flunitrazepam, and pentobarbital modulation of GABAA receptors expressed in mammalian cells and xenopus oocytes
5. Comparison of anaesthetic and non-anaesthetic effects on depolarization-evoked glutamate and GABA release from mouse cerebrocortical slices
6. Exaggerated anesthetic requirements in the preferentially anesthetized brain
7. Does the brain influence somatic responses to noxious stimuli during isoflurane anesthesia?
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15. Chronic catheterization of the spinal sub-arachnoid space
16. Intrathecal administration of N-methyl-D-aspartate receptor antagonist reduces the minimum alveolar anaesthetic concentration of isoflurane in rats
17. Intrathecally administered NMDA receptor antagonists reduce the MAC of isoflurane in rats
18. Interactions between NMDA and AMPA glutamate receptor antagonists during halothane anesthesia in the rat
19. Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon