메뉴 건너뛰기




Volumn 47, Issue 6, 2001, Pages 541-544

A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide

Author keywords

Cyproheptadine; Diclofenac; DMXAA; Drug interaction; Thalidomide

Indexed keywords

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; CYPROHEPTADINE; DICLOFENAC; SN 24350; THALIDOMIDE;

EID: 0035001126     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800100285     Document Type: Article
Times cited : (11)

References (31)
  • 1
    • 0032100604 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by thalidomide requires metabolic activation which is species-dependent
    • 1. Bauer KS, Dixon SC, Figg WD (1998) Inhibition of angiogenesis by thalidomide requires metabolic activation which is species-dependent. Biochem Pharmacol 55:1827-1834
    • (1998) Biochem Pharmacol , vol.55 , pp. 1827-1834
    • Bauer, K.S.1    Dixon, S.C.2    Figg, W.D.3
  • 3
    • 0022625689 scopus 로고
    • Teratogen metabolism: Thalidomide activation is mediated by cytochrome P450
    • 3. Braun AG, Harding FA, Weinreb SL (1986) Teratogen metabolism: thalidomide activation is mediated by cytochrome P450. Toxicol Appl Pharmacol 82:175-179
    • (1986) Toxicol Appl Pharmacol , vol.82 , pp. 175-179
    • Braun, A.G.1    Harding, F.A.2    Weinreb, S.L.3
  • 4
    • 0028875109 scopus 로고
    • Specificity of human UDP-glucuronosyl-transferases and xenobiotic glucuronidation
    • 4. Burchell B, Brieley CH, Rance D (1995) Specificity of human UDP-glucuronosyl-transferases and xenobiotic glucuronidation. Life Sci 57:1818-1831
    • (1995) Life Sci , vol.57 , pp. 1818-1831
    • Burchell, B.1    Brieley, Ch.2    Rance, D.3
  • 5
    • 0017587522 scopus 로고
    • Effect of thalidomide on a promsimian: Greater galago (Galago crassicaudatus)
    • 5. Butler H (1977) Effect of thalidomide on a promsimian: greater galago (Galago crassicaudatus). J Med Primatol 6:319-324
    • (1977) J Med Primatol , vol.6 , pp. 319-324
    • Butler, H.1
  • 6
    • 0000136391 scopus 로고
    • Preparation of one optical antipode of 2-phthalimidoglutarimide
    • 6. Casini G, Ferappi M (1964) Preparation of one optical antipode of 2-phthalimidoglutarimide. Farmaco 19:563-565
    • (1964) Farmaco , vol.19 , pp. 563-565
    • Casini, G.1    Ferappi, M.2
  • 7
    • 0031846669 scopus 로고    scopus 로고
    • Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid: Concomitant reduction of serum tumour necrosis factor-alpha and enhancement of anti-tumour activity
    • 7. Ching L-M, Browne WL, Tchernegovski R, Gregory T, Baguley BC, Palmer BD (1998) Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid: concomitant reduction of serum tumour necrosis factor-alpha and enhancement of anti-tumour activity. Br J Cancer 78:336-343
    • (1998) Br J Cancer , vol.78 , pp. 336-343
    • Ching, L.-M.1    Browne, W.L.2    Tchernegovski, R.3    Gregory, T.4    Baguley, B.C.5    Palmer, B.D.6
  • 8
    • 0013895422 scopus 로고
    • Teratogenic activity of thalidomide in the rabbit
    • 8. Fabro S, Smith RL (1966) Teratogenic activity of thalidomide in the rabbit. J Pathol Bacteriol 91:511-519
    • (1966) J Pathol Bacteriol , vol.91 , pp. 511-519
    • Fabro, S.1    Smith, R.L.2
  • 9
    • 0001867498 scopus 로고    scopus 로고
    • Thalidomide: A prodrug that inhibits angiogenesis
    • In: Teicher BA (ed). Humana Press, Totowa
    • 9. Figg WD, Reed E, Green S, Pluda JM (1999) Thalidomide: a prodrug that inhibits angiogenesis. In: Teicher BA (ed) Antiangiogenic agents in cancer therapy. Humana Press, Totowa, pp 407-422
    • (1999) Antiangiogenic Agents in Cancer Therapy , pp. 407-422
    • Figg, W.D.1    Reed, E.2    Green, S.3    Pluda, J.M.4
  • 10
    • 0028948889 scopus 로고
    • Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides
    • 10. Green MD, Bishop WP, Tephly TR (1995) Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides. Drug Metab Dispos 23:299-302
    • (1995) Drug Metab Dispos , vol.23 , pp. 299-302
    • Green, M.D.1    Bishop, W.P.2    Tephly, T.R.3
  • 11
    • 0031765698 scopus 로고    scopus 로고
    • Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3
    • 11. Green MD, King CD, Mojarrabi B, Mackenzie PI, Tephly TR (1998) Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3. Drug Metab Dispos 26:507-512
    • (1998) Drug Metab Dispos , vol.26 , pp. 507-512
    • Green, M.D.1    King, C.D.2    Mojarrabi, B.3    Mackenzie, P.I.4    Tephly, T.R.5
  • 12
    • 0033052183 scopus 로고    scopus 로고
    • Plasma disposition, metabolism and excretion of the experimental antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the mouse, rat and rabbit
    • 12. Kestell P, Paxton JW, Rewcastle GW, Dunlop I, Baguley BC (1999) Plasma disposition, metabolism and excretion of the experimental antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the mouse, rat and rabbit. Cancer Chemother Pharmacol 43:323-330
    • (1999) Cancer Chemother Pharmacol , vol.43 , pp. 323-330
    • Kestell, P.1    Paxton, J.W.2    Rewcastle, G.W.3    Dunlop, I.4    Baguley, B.C.5
  • 13
    • 0033895294 scopus 로고    scopus 로고
    • Modulation of the plasma pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid by thalidomide in mice
    • 13. Kestell P, Zhao L, Ching L-M, Baguley BC, Paxton JW (2000) Modulation of the plasma pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid by thalidomide in mice. Cancer Chemother Pharmacol 46:135-141
    • (2000) Cancer Chemother Pharmacol , vol.46 , pp. 135-141
    • Kestell, P.1    Zhao, L.2    Ching, L.-M.3    Baguley, B.C.4    Paxton, J.W.5
  • 14
    • 0030560905 scopus 로고    scopus 로고
    • Thalidomide as an anti-TNF-alpha inhibitor - Implications for clinical use
    • 14. Klausner JD, Freedman VH, Kaplan G (1996) Thalidomide as an anti-TNF-alpha inhibitor - implications for clinical use. Clin Immunol Immunopathol 81:219-223
    • (1996) Clin Immunol Immunopathol , vol.81 , pp. 219-223
    • Klausner, J.D.1    Freedman, V.H.2    Kaplan, G.3
  • 16
    • 0031022925 scopus 로고    scopus 로고
    • Preclinical prediction of factors influencing the elimination of 5,6-dimethylxanthenone-4-acetic acid, a new anticancer drug
    • 16. Miners JO, Valente L, Lillywhite KJ, Mackenzie PI, Burchell B, Baguley BC, Kestell P (1997) Preclinical prediction of factors influencing the elimination of 5,6-dimethylxanthenone-4-acetic acid, a new anticancer drug. Cancer Res 57:284-289
    • (1997) Cancer Res , vol.57 , pp. 284-289
    • Miners, J.O.1    Valente, L.2    Lillywhite, K.J.3    Mackenzie, P.I.4    Burchell, B.5    Baguley, B.C.6    Kestell, P.7
  • 17
    • 0029962068 scopus 로고    scopus 로고
    • Suppression of cytochrome P450-and UDP glucuronosyltransferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes
    • 17. Monshouwer M, Witkamp RF, Numeijer SM, van Amsterdam JG, van Miert ASJPAM (1996) Suppression of cytochrome P450-and UDP glucuronosyltransferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes. Toxicol Appl Pharmacol 137:237-244
    • (1996) Toxicol Appl Pharmacol , vol.137 , pp. 237-244
    • Monshouwer, M.1    Witkamp, R.F.2    Numeijer, S.M.3    Van Amsterdam, J.G.4    Van Miert, A.S.J.P.A.5
  • 18
    • 0032411785 scopus 로고    scopus 로고
    • Chiral inversion and hydrolysis of thalidomide: Mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites
    • 18. Reist M, Carrupt PA, Francotte E, Testa B (1998) Chiral inversion and hydrolysis of thalidomide: mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites. Chem Res Toxicol 11:1521-1528
    • (1998) Chem Res Toxicol , vol.11 , pp. 1521-1528
    • Reist, M.1    Carrupt, P.A.2    Francotte, E.3    Testa, B.4
  • 19
    • 0024605005 scopus 로고
    • Potential antitumour agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumour in vivo
    • 19. Rewcastle GW, Atwell GJ, Baguley BC, Calveley SB, Denny WA (1989) Potential antitumour agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumour in vivo. J Med Chem 32:793-799
    • (1989) J Med Chem , vol.32 , pp. 793-799
    • Rewcastle, G.W.1    Atwell, G.J.2    Baguley, B.C.3    Calveley, S.B.4    Denny, W.A.5
  • 21
    • 0013804543 scopus 로고
    • The metabolism of thalidomide: The spontaneous hydrolysis of thalidomide in solution
    • 21. Schumacher H, Smith RL, Williams RT (1965) The metabolism of thalidomide: the spontaneous hydrolysis of thalidomide in solution. Br J Pharmacol 25:324-337
    • (1965) Br J Pharmacol , vol.25 , pp. 324-337
    • Schumacher, H.1    Smith, R.L.2    Williams, R.T.3
  • 24
    • 0032998193 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia
    • 24. Takemura S, Minamiyama Y, Imaoka S, Funae Y, Hirohashi K, Inoue M, Kinoshita H (1999) Hepatic cytochrome P450 is directly inactivated by nitric oxide, not by inflammatory cytokines, in the early phase of endotoxemia. J Hepatol 30:1035-1044
    • (1999) J Hepatol , vol.30 , pp. 1035-1044
    • Takemura, S.1    Minamiyama, Y.2    Imaoka, S.3    Funae, Y.4    Hirohashi, K.5    Inoue, M.6    Kinoshita, H.7
  • 25
    • 0033630619 scopus 로고    scopus 로고
    • Metabolism of thalidomide in human microsomes, cloned human cytochrome p-450 isozymes, and Hansen's disease patients
    • 25. Teo SK, Sabourin PJ, O'Brien K, Kook KA, Thomas SD (2000) Metabolism of thalidomide in human microsomes, cloned human cytochrome P-450 isozymes, and Hansen's disease patients. J Biochem Mol Toxicol 14:140-147
    • (2000) J Biochem Mol Toxicol , vol.14 , pp. 140-147
    • Teo, S.K.1    Sabourin, P.J.2    Brien, K.3    Kook, K.A.4    Thomas, S.D.5
  • 26
    • 0035001007 scopus 로고    scopus 로고
    • Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetic of 5,6-dimethylxanthenone-4-acetic (DMXAA)
    • in press
    • 26. Zhao L, Ketsell P, Zhuang L, Baguley BC (2001) Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetic of 5,6-dimethylxanthenone-4-acetic (DMXAA). Cancer Chemother Pharmacol (in press)
    • (2001) Cancer Chemother Pharmacol
    • Zhao, L.1    Ketsell, P.2    Zhuang, L.3    Baguley, B.C.4
  • 27
    • 0032589950 scopus 로고    scopus 로고
    • Determination of two major metabolites of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in hepatic microsomal incubations by high-performance liquid chromatography with fluorescence detection
    • 27. Zhou SF, Paxton JW, Tingle MD, McCall J, Kestell P (1999) Determination of two major metabolites of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in hepatic microsomal incubations by high-performance liquid chromatography with fluorescence detection. J Chromatogr B 734:129-136
    • (1999) J Chromatogr B , vol.734 , pp. 129-136
    • Zhou, S.F.1    Paxton, J.W.2    Tingle, M.D.3    McCall, J.4    Kestell, P.5
  • 28
    • 0033673590 scopus 로고    scopus 로고
    • Identification of the human liver cytochrome P450 isozyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid
    • 28. Zhou SF, Paxton JW, Tingle MD, Kestell P (2000) Identification of the human liver cytochrome P450 isozyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid. Drug Metab Dispos 28:1449-1456
    • (2000) Drug Metab Dispos , vol.28 , pp. 1449-1456
    • Zhou, S.F.1    Paxton, J.W.2    Tingle, M.D.3    Kestell, P.4
  • 29
    • 0034743321 scopus 로고    scopus 로고
    • In vitro and in vivo kinetic interactions of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid with thalidomide and diclofenac
    • in press
    • 29. Zhou SF, Paxton JW, Tingle MD, Kestell P, Ching L-M (2001) In vitro and in vivo kinetic interactions of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid with thalidomide and diclofenac. Cancer Chemother Pharmacol (in press)
    • (2001) Cancer Chemother Pharmacol
    • Zhou, S.F.1    Paxton, J.W.2    Tingle, M.D.3    Kestell, P.4    Ching, L.-M.5
  • 30
    • 0035038182 scopus 로고    scopus 로고
    • Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and blood cells in various species
    • in press
    • 30. Zhou SF, Paxton JW, Kestell P, Tingle MD (2001) Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and blood cells in various species. J Pharm Pharmacol (in press)
    • (2001) J Pharm Pharmacol
    • Zhou, S.F.1    Paxton, J.W.2    Kestell, P.3    Tingle, M.D.4
  • 31
    • 0034947850 scopus 로고    scopus 로고
    • Identification and reactivity of the major metabolite (b-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans
    • in press
    • 31. Zhou SF, Paxton JW, Tingle MD, Kestell P, Jameson MB, Thomson PI, Baguley BC (2001) Identification and reactivity of the major metabolite (b-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans. Xenobiotica (in press)
    • (2001) Xenobiotica
    • Zhou, S.F.1    Paxton, J.W.2    Tingle, M.D.3    Kestell, P.4    Jameson, M.B.5    Thomson, P.I.6    Baguley, B.C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.