Intracellular localization of the radiation enhancer motexafin gadolinium using interferometric fourier fluorescence microscopy

Journal of Pharmacology and Experimental Therapeutics

Volumn 297, Issue 3, 2001, Pages 888-894

  Woodburn, Kathryn W ^a  

^a PHARMACYCLICS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM TEXAPHYRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CELL NUCLEUS; CELL ORGANELLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; FIBROSARCOMA; FLUORESCENCE MICROSCOPY; GOLGI COMPLEX; IONIZING RADIATION; LYSOSOME; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOISOTOPE DISTRIBUTION; SARCOMA;

ANIMALS; BIOLOGICAL TRANSPORT; CELL NUCLEUS; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; ENDOPLASMIC RETICULUM; FLUORESCENT DYES; GOLGI APPARATUS; LYSOSOMES; METALLOPORPHYRINS; MICE; MICROSCOPY, FLUORESCENCE; MICROSCOPY, INTERFERENCE; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PHOTOCHEMISTRY; RADIATION-SENSITIZING AGENTS; SARCOMA; SPECTROMETRY, FLUORESCENCE; TUMOR CELLS, CULTURED;

EID: 0034998914     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. 2 with cell iron by zinc-metallothionein. Chem Biol Interact 115: 85-107.
2. Howell KE, Devaney E and Gruenberg J (1989) Subcellular fractionation of tissue culture cells. Trends Biol Sci 14:44-47.
3. Malik Z, Dishi M and Garini Y (1996) Fourier transform multipixel spectroscopy and spectral imaging of protoporphyrin in single melanoma cells. Photochem Photobiol 63:608-614.
4. Minamikawa T, Sriratana A, Williams DA, Bowser DN, Hill JS and Nagley P (1999) Chloromethyl-X-rosamine (MitoTracker Red) photosensitizes mitochondria and induces apoptosis in intact human cells. J Cell Sci 112:2419-2430.
5. Miller RA, Woodburn K, Fan Q, Renschler MF, Sessler JL and Koutcher JA (1999) In vivo animal studies with gadolinium (III) texaphyrin as a radiation enhancer. Int J Rad Oncol Biol Phys 45:981-989.
6. Pasquali C, Fialka I and Huber LA (1999) Subcellular fractionation, electromigration analysis and mapping of organelles. J Chromatogr B 722:89-102.
7. Richards-Kortum R and Sevick-Muraca E (1996) Quantitative optical spectroscopy for tissue diagnosis. Annu Rev Phys Chem 47:555-606.
8. Rockwell SC, Kallman RF and Fajardo LF (1972) Characteristics of a serially transplanted mouse mammary tumor and its tissue culture adapted derivative. J Natl Cancer Inst 49:735-749.
9. Rowinsky ER (1999) Novel radiation sensitizers targeting tissue hypoxia. Oncology 13:61-70.
10. Schröck E, du Manoir S, Veldman T, Schoell B, Wienberg J, Ferguson-Smith MA, Ning Y, Ledbetter DH, Bar-Am I, Soenksen D, et al. (1996) Multicolor spectral karyotyping of human chromosomes. Science (Wash DC) 273:494-497.
11. Sessler JL, Tvermoes NA, Guldi DM, Mody TD and Allen WE (1999) One-electron reduction and oxidation studies of the radiation sensitizer gadolinium(III) texaphyrin (PCI-0120) and other water soluble metallotexaphyrins. J Phys Chem 103:787-794.
12. Twentyman PR, Brown JM, Gray JW, Franko AJ, Scoles MA and Kallman RF (1980) A new mouse tumor model system (Rif-1) for comparison of end-point studies. J Natl Cancer Inst 64:595-604.
13. Woodburn KW, Vardaxis NJ, Hill JS, Kaye AH and Phillips DR (1991) Subcellular localization of porphyrins using confocal laser scanning microscopy. Photochem Photobiol 54:725-732.
14. Young SW, Qing F, Harriman A, Sessler JL, Dow WC, Mody TD, Hemmi GW, Hao Y and Miller RA (1996) Gadolinium(III) texaphyrin: a tumor selective radiation sensitizer that is detectable by MRI. Proc Natl Acad Sci USA 93:6610-6615.