mRNA expression of novel cgrp1 receptors and their activity-modifying proteins in hypoxic rat lung

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 280, Issue 3 24-3, 2001, Pages

  Qing, Xin ^a   Svaren, John ^a   Keith, Ingegerd M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Calcitonin receptor like receptor; RDC 1; Real time quantitative reverse transcription polymerase chain reaction; Receptor activity modifying protein 1; Receptor activity modifying protein 2; Receptor activity modifying protein 3; Semiquantitative reverse transcription polymerase chain reaction

Indexed keywords

ADRENOMEDULLIN; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; MESSENGER RNA; RECEPTOR ACTIVITY MODIFYING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; HYPOXIA; LUNG CIRCULATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; VASODILATATION;

EID: 0034998155     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.280.3.l547     Document Type: Article

References (39)

1. Aiyar N, Rand K, Elshourbagy NA, Zeng Z, Adamou JE, Bergsma DJ, and Li Y. A cDNA encoding the calcitonin gene-related peptide type 1 receptor. J Biol Chem 271: 11325-11329, 1996.
2. Amara SG, Jonas V, Rosenfeld MG, Ong ES, and Evans RM. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature 298: 240-244, 1982.
3. Dennis T, Fournier A, Cadieux A, Pomerleau F, Jolicoeur FB, St. Pierre S, and Quirion R. hCGRP8-37, a calcitonin gene-related peptide antagonist revealing calcitonin gene-related peptide receptor heterogeneity in brain and periphery. J Pharmacol Exp Ther 254: 123-128, 1990.
4. Entzeroth M, Doods HN, Wieland HA, and Wienen W. Adrenomedullin mediates vasodilation via CGRP1 receptors. Life Sci 56: L19-L25, 1995.
5. Fluhmann B, Muff R, Hunziker W, Fischer JA, and Born W. A human orphan calcitonin receptor-like structure. Biochem Biophys Res Commun 206: 341-347, 1995.
6. Fraser NJ, Wise A, Brown J, McLatchie LM, Main MJ, and Foord SM. The amino terminus of receptor activity-modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor. Mol Pharmacol 55: 1054-1059, 1999.
7. Hjelmqvist H, Keil R, Mathai M, Hubschle T, and Gerstberger R. Vasodilation and glomerular binding of adrenomedulin in rabbit kidney are not CGRP receptor mediated. Am J Physiol Regulatory Integrative Comp Physiol 273: R716-R724, 1997.
8. Ichiki Y, Kitamura K, Kangawa K, Kawamoto M, Matsuo H, and Eto T. Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett 338: 6-10, 1994.
9. Kapas S, Catt KJ, and Clark AJ. Cloning and expression of cDNA encoding a rat adrenomedullin receptor. J Biol Chem 270: 25344-25347, 1995.
10. Kapas S and Clark AJ. Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor. Biochem Biophys Res Commun 217: 832-838, 1995.
11. Keith IM and Ekman R. Calcitonin gene-related peptide in hamster lung and its coexistence with serotonin: a chemical and immunocytochemical study. Regul Pept 22: 315-323, 1988.
12. Keith IM, Ekman R, Kraiczi H, and Sandler R. CGRP treatment of chronic hypoxia-induced pulmonary hypertension in rats (Abstract). FASEB J 9: A601, 1995.
13. Keith IM, Pelto-Huikko M, Schalling M, and Hökfelt T. Calcitonin gene-related peptide and its mRNA in pulmonary neuroendocrine cells and ganglia. Histochemistry 96: 311-315, 1991.
14. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, and Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 192: 553-560, 1993.
15. Kitamura K, Sakata J, Kangawa K, Kojima M, Matsuo H, and Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem Biophys Res Commun 194: 720-725, 1993. [Corrigenda. Biochem Biophys Res Commun 202: July 1994, p. 643.]
16. Lang MG, Paterno R, Faraci FM, and Heistad DD. Mechanisms of adrenomedullin-induced dilatation of cerebral arterioles. Stroke 28: 181-185, 1997.
17. Libert F, Parmentier M, Lefort A, Dinsart C, Van Sande J, Maenhaut C, Simons MJ, Dumont JE, and Vassart G. Selective amplification and cloning of four new members of the G protein-coupled receptor family. Science 244: 569-572, 1989.
18. Luu TN, Dashwood MR, Chester AH, Muddle JR, and Yacoub MH. Calcitonin gene-related peptide in healthy and atheromatous human epicardial coronary arteries. Function and receptor characterization. J Vasc Res 32: 93-99, 1995.
19. Mak JC and Barnes PJ. Autoradiographic localization of calcitonin gene-related peptide (CGRP) binding sites in human and guinea pig lung. Peptides 9: 957-963, 1988.
20. Mannan MM, Springall DR, Enard C, Moradoghli-Haftvani A, Eddahibi S, Adnot S, and Polak JM. Decreased endothelium-dependent pulmonary vasodilator effect of calcitonin gene-related peptide in hypoxic rats contrasts with increased binding sites. Eur Respir J 8: 2029-2037, 1995.
21. Marinoni E, Di Iorio R, Alo P, Villaccio B, Alberini A, and Cosmi EV. Immunohistochemical localization of adrenomedullin in fetal and neonatal lung. Pediatr Res 45: 282-285, 1999.
22. McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, and Foord SM. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393: 333-339, 1998.
23. Nandha KA, Taylor GM, Smith DM, Owji AA, Byfield PG, Ghatei MA, and Bloom SR. Specific adrenomedullin binding sites and hypotension in the rat systemic vascular bed. Regul Pept 62: 145-151, 1996.
24. Njuki F, Nicholl CG, Howard A, Mak JC, Barnes PJ, Girgis SI, and Legon S. A new calcitonin-receptor-like sequence in rat pulmonary blood vessels. Clin Sci (Colch) 85: 385-388, 1993.
25. Nuki C, Kawasaki H, Kitamura K, Takenaga M, Kangawa K, Eto T, and Wada A. Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds. Biochem Biophys Res Commun 196: 245-251, 1993.
26. Owji AA, Smith DM, Coppock HA, Morgan DG, Bhogal R, Ghatei MA, and Bloom SR. An abundant and specific binding site for the novel vasodilator adrenomedullin in the rat. Endocrinology 136: 2127-2134, 1995.
27. Quirion R, Van Rossum D, Dumont Y, St. Pierre S, and Fournier A. Characterization of CGRP1 and CGRP2 receptor subtypes. Ann NY Acad Sci 657: 88-105, 1992.
28. Rosenfeld MG, Mermod JJ, Amara SG, Swanson LW, Sawchenko PE, Rivier J, Vale WW, and Evans RM. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature 304: 129-135, 1983.
29. Sakata J, Shimokubo T, Kitamura K, Nakamura S, Kangawa K, Matsuo H, and Eto T. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. Biochem Biophys Res Commun 195: 921-927, 1993.
30. Sams A and Jansen-Olesen I. Expression of calcitonin receptor-like receptor and receptor-activity-modifying proteins in human cranial arteries. Neurosci Lett 258: 41-44, 1998.
31. Terenghi G, Polak JM, Ghatei MA, Mulderry PK, Butler JM, Unger WG, and Bloom SR. Distribution and origin of calcitonin gene-related peptide (CGRP) immunoreactivity in the sensory innervation of the mammalian eye. J Comp Neurol 233: 506-516, 1985.
32. Tjen-A-Looi S, Ekman R, Lippton H, Cary J, and Keith I. CGRP and somatostatin modulate chronic hypoxic pulmonary hypertension. Am J Physiol Heart Circ Physiol 263: H681-H690, 1992.
33. Tjen-A-Looi S, Kraiczi H, Ekman R, and Keith IM. Sensory CGRP depletion by capsaicin exacerbates hypoxia-induced pulmonary hypertension in rats. Regul Pept 74: 1-10, 1998.
34. Umeda Y and Arisawa M. Characterization of calcitonin gene-related peptide (CGRP) receptors in guinea pig lung. Jpn J Pharmacol 51: 377-384, 1989.
35. Van Rossum D, Hanisch UK, and Quirion R. Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors. Neurosci Biobehav Rev 21: 649-678, 1997.
36. Watkins DJ and Burcher E. Autoradiographic localization of calcitonin gene-related peptide receptors in guinea pig respiratory tract: effect of capsaicin pretreatment. Peptides 16: 683-692, 1995.
37. Wimalawansa SJ. Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials. Endocr Rev 17: 533-585, 1996.
38. Wimalawansa SJ. Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily. Crit Rev Neurobiol 11: 167-239, 1997.
39. Zhao L, Brown LA, Owji AA, Nunez DJ, Smith DM, Ghatei MA, Bloom SR, and Wilkins MR. Adrenomedullin activity in chronically hypoxic rat lungs. Am J Physiol Heart Circ Physiol 271: H622-H629, 1996.