Phospholipase C inhibitors attenuate arrhythmias induced by κ-receptor stimulation in the isolated rat heart

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 10, 1998, Pages 2103-2110

  Bian, Jin Song ^a   Zhang, Wei Min ^a   Xia, Qiang ^a   Wong, Tak Ming ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Arrhythmia; G protein; Inositol 1,4,5 trisphosphate (IP3); Intracellular Ca2+; Isolated rat heart; Pertussis toxin (PTX); Phospholipase C (PLC); U50488; opioid receptor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; KAPPA OPIATE RECEPTOR; NEOMYCIN; NORBINALTORPHIMINE; PHOSPHOLIPASE C INHIBITOR; STREPTOMYCIN;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; HEART ARRHYTHMIA; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0032190917     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0774     Document Type: Article

References (30)

1. 2+ paradox injury in rat heart. Circ Res 74: 360-367.
2. BIAN JS, WANG HX, ZHANG WM, WONG TM, 1998. Effects of κ-opioid receptor stimulation in the heart and the involvement of protein kinase C. Br J Pharmacol 124: 600-606.
3. CURTIS MJ, WALKER MJA, 1988. Quantitation of arrhythmias using scoring systems: an examination of seven scores in an in vivo model of regional myocardial ischaemia. Cardiovasc Res 22: 656-665.
4. DONG H, SHENG JZ, LEE CM, WONG TM, 1993. Calcium antagonistic and antiarrhythmic actions of CPU-23, a substituted tetrahydroisopuinoline. Br J Pharmacol 109: 113-119.
5. 3 release. Circulation 91: 2712-2716.
6. FAGBEMI O, LEPRAN I, PARRATT JR, SZEKERES L, 1982. Naloxone inhibits early arrhythmias resulting from acute coronary ligation. Br J Pharmacol 76: 504-506.
7. FLEMING JW, WISLER PL, WATANABE AM, 1992. Signal transduction by G proteins in cardiac tissues. Circulation 85: 420-433.
8. + exchanger. Cardiologia 38: 25-36.
9. 2+ sensitivity in intact and skinned muscles from normal and diseased human myocardium. Cir Res 67: 744-752.
10. HUANG XD, LEE AYS, WONG TM, ZHAN CY, ZHOU YY, 1986. Naloxone inhibits arrhythmias induced by coronary artery occlusion and reperfusion in anaesthetized dogs. Br J Pharmacol 87: 475-477.
11. JACOBSEN AN, DU XJ, LAMBERT KA, DART AM, WOODCOCK EA, 1996. Arrhythmogenic action of thrombin during myocardial reperfusion via release of inositol 1,4,5-triphosphate. Circulation 93: 23-26.
12. LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ, 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
13. PEPE S, XIAO RP, HOHL C, ALTSCHULD R, LAKATTA EG, 1997. 'Cross talk' between opioid peptide and adrenergic receptor signaling in isolated rat heart. Circulation 95: 2122-2129.
14. PIACENTINI L, WAINWRIGHT CL, PARRATT J, 1993. The antiarrhythmic effect of ischaemic preconditioning in isolated rat heart involves a pertussis toxin sensitive mechanism. Cardiovasc Res 27: 674-680.
15. 2+ accumulation in cardiac sarcoplasmic reticulum. J Biol Chem 265: 4302-4308.
16. 2+ elevations evoked by kappa-opioid receptor in rat myocytes. Eur J Pharmacol 307: 323-329.
17. 2+ in rat ventricular myocytes. Life Sci 59: 2181-2186.
18. i in myocytes. Am J Physiol 272: C560-C564.
19. SITSAPESAN R, PARRATT JR, 1989. The effect of drugs interacting with opioid receptors on the early ventricular arrhythmias arising from myocardial ischaemia. Br J Pharmacol 97: 795-800.
20. THANDROYAN FT, MORRIS AC, HAGLER HK, ZIMAN B, PAI L, WILERSON JT, BUJA LM, 1991. Intracellular calcium transients and arrhythmia in isolated heart cells. Circ Res 69: 810-819.
21. 2+ in cardiac myocytes. Am J Physiol 261: H1671-H1674.
22. 2+ release from an intracellular pool in myocytes and neurons. Circ Res 70: 66-81.
23. WONG TM, LEE AYS, 1987. Chronic morphine treatment reduced the incidence of cardiac arrhythmia induces by dynorphin (1-13) or myocardial ischaemia and reperfusion. Neurosci Lett 77: 61-65.
24. WONG TM, LEE AYS TAI KK, 1990. Effects of drugs interacting with opioid receptors during normal perfusion or ischaemia and reperfusion - an attempt to identify cardiac opioid receptor subtype(s) involved in arrhythmogenesis. J Mol Cell Cardiol 22: 1167-1175.
25. 3 during myocardial ischemia and its relationship to the development of arrhythmias. J Mol Cell Cardiol 28: 2129-2138.
26. XIA Q, SHENG JZ, TAI KK, WONG TM, 1994. Effects of chronic U50,488H treatment on binding and mechanical responses of the rat hearts. J Pharmacol Exp Ther 268: 930-934.
27. XIAO RP, PEPE S, SPURGEON HA, CAPOGROSSI MC, LAKATTA EG, 1997. Opioid peptide receptor stimulation reverses beta-adrenergic effects in rat heart cells. Am J Physiol 41: H797-H805.
28. YU XC, LI HX, WANG HX, WONG TM, 1998. U50,488H inhibits effects of norepinephrine in rat cardiomyocytes. Cross-talk between kappa-opioid and beta-adrenergic receptors. J Mol Cell Cardiol 30: 237-251.
29. 3]U69593 binding and the cardiac effects of U50,488H by calcium channel blockers in the rat heart. Br J Pharmacol 120: 827-832.
30. 2+ release from cardiac sarcoplasmic reticulum. Pflügers Arch 418: 1-6.