The prognostic impact of karyotypic subgroups in myelodysplastic syndromes is strongly modified by sex

British Journal of Haematology

Volumn 113, Issue 2, 2001, Pages 347-356

  Mauritzson, N ^a,b,c   Johansson, B ^a   Rylander, L ^b   Albin, M ^c   Stromberg U ^c   Billstrom R ^a   Ahlgren, T ^a   Mikoczy, Z ^a   Mitelman, F ^a   Hagmar, L ^a   Nilsson, P G ^a  

^a Division of Haematology   (Sweden)

^b Department of Clinical Genetics ^*  (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Karyotype; Myelodysplastic syndromes; Prognosis; Sex; Smoking

Indexed keywords

ADULT; AGE; AGED; ARTICLE; CANCER SURVIVAL; CHROMOSOME 5Q; CONTROLLED STUDY; CYTOGENETICS; FEMALE; GENDER; GENE DELETION; HUMAN; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROGNOSIS; SMOKING HABIT;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; KARYOTYPING; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SEX FACTORS; SMOKING; SURVIVAL RATE;

EID: 0034995677     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02750.x     Document Type: Article

References (41)

1. Fluorescence in situ hybridization analyses of hematologic malignancies reveal frequent cytogenetically unrecognized 12p rearrangements
2. Influence of cigarette smoking on the presentation and course of chronic myelogenous leukemia
3. Primary myelodysplastic syndromes: Analysis of prognostic factors in 235 patients and proposals for an improved scoring system
4. FAB and MIC classification of myelodysplastic syndromes: Points of controversy
5. Proposals for the classification of the myelodysplastic syndromes
6. The chronic myeloid leukaemias: Guidelines for distinguishing chronic granulocytic, atypical chronic myeloid, and chronic myelomonocytic leukaemia
7. Normal bone marrow karyotype in acute leukemia or myelodysplasia following rheumatoid arthritis?
8. Bone marrow karyotype and prognosis in primary myelodysplastic syndromes
9. Immune-mediated complications in patients with myelodysplastic syndromes - Clinical and cytogenetic features
10. Clonal CD5-positive B lymphocytes in myelodysplastic syndrome with systemic vasculitis and trisomy 8
11. Smoking and myelodysplastic syndromes
12. Cytogenetic evolution following the transformation of myelodysplastic syndrome to acute myelogenous leukemia: Implications on the overlap between the two diseases
13. International scoring system for evaluating prognosis in myelodysplastic syndromes
14. Chronic myelomonocytic leukemia: Single entity or heterogeneous disorder? A prospective multicenter study of 100 patients
15. Refractory anemia with excess of blasts: A multivariate analysis of prognostic factors in 91 patients and a simplified scoring system for predicting survival
16. Ten novel 11q23 chromosomal partner sites
17. Cigarette smoking, blast crisis, and survival in chronic myeloid leukemia
18. Molecular characterization of 12p abnormalities in hematologic malignancies: Deletion of KIP1, rearrangement of TEL, and amplification of CCND2
19. Cytogenetics of secondary myelodysplasia (sMDS) and acute nonlymphocytic leukemia (sANLL)
20. Trisomy 19 as the sole chromosomal anomaly in hematologic neoplasms
21. Deletion of chromosome arm 3p in hematologic malignancies
22. Utility of the FAB classification for myelodysplastic syndromes: Investigation of prognostic factors in 237 cases
23. Application of the International Prognostic Scoring System for myelodysplastic syndromes
24. New system for assessing the prognosis of refractory anemia patients
25. A single-center population-based consecutive series of 1500 cytogenetically investigated adult hematologic malignancies: Karyotypic features in relation to morphology, age and gender
26. Trisomy 14 in atypical chronic myeloid leukemia
27. Chromosome pattern, occupation, and clinical features in patients with acute non-lymphocytic leukemia
28. High resolution analysis of the 5q-marker chromosome in refractory anemia
29. Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: A report on 408 cases
30. Prognostic factors in myelodysplastic syndromes: Critical analysis of the impact of age and sex and failure to identify a very-low-risk group using standard mortality ratio techniques
31. Myelodysplastic syndromes: A scoring system with prognostic significance
32. Cytogenetic abnormalities in primary myelodysplastic syndrome are highly predictive of outcome after allogeneic bone marrow transplantation
33. Chromosome abnormalities in myelodysplastic syndromes
34. Minimal diagnostic criteria for the myelodysplastic syndrome
35. NRAS mutations are rare in acute myeloid leukaemias with t (8:21) or inv (16)
36. MDS and AML with trisomy 8 as the sole chromosome aberration show different sex ratios and prognostic profiles: A study of 115 published cases
37. Cross-validation of prognostic scores in myelodysplastic syndromes on 386 patients from a single institution confirms importance of cytogenetics
38. Clinical implications of chromosomal abnormalities in 401 patients with myelodysplastic syndromes: A multicentric study in Japan
39. Prognostic factors in the myelodysplastic syndromes
40. Refined chromosome study helps define prognostic subgroups in most patients with primary myelodysplastic syndrome and acute myelogenous leukaemia