Molecular characterization of 12p abnormalities in hematologic malignancies: Deletion of KIP1, rearrangement of TEL, and amplification of CCND2

Blood

Volumn 87, Issue 1, 1996, Pages 324-330

  Höglund, Mattias ^a   Johansson, Bertil ^b   Pedersen Bjergaard, Jens ^b   Marynen, Peter ^b   Mitelman, Felix ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; BURKITT LYMPHOMA; CELL CYCLE; CHROMOSOME 12P; CHROMOSOME ABERRATION; CHROMOSOME REARRANGEMENT; CLINICAL ARTICLE; FEMALE; GENE AMPLIFICATION; GENE DELETION; HUMAN; HUMAN CELL; MALE; MYELODYSPLASTIC SYNDROME; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; SCHOOL CHILD; TUMOR SUPPRESSOR GENE;

EID: 0030034007     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.1.324.bloodjournal871324     Document Type: Article

References (38)

1. Mitelman F: Catalog of Chromosome Aberrations in Cancer (ed 5). New York, NY, Wiley-Liss, 1994
2. Johansson B, Mertens F, Mitelman F: Cytogenetic deletion maps of hematologic neoplasms: Circumstantial evidence for tumor suppressor loci. Genes Chromosom Cancer 8:205, 1993
3. Johansson B, Mertens F, Heim S, Kristofferson U, Mitelman F: Cytogenetics of secondary myelodysplasia (sMDS) and acute nonlymphocytic leukemia (sANLL). Eur J Haematol 47:17, 1991
4. Pedersen-Bjergaard J, Philip P, Pedersen N, Hou-Jensen K, Svejgaard A, Jensen G, Nissen NI: Acute nonlymphocytic leukemia, preleukemia and acute myeloproliferative syndrome secondary to treatment of other malignant diseases. Cancer 54:452, 1984
5. Golub TR, Barker GF, Lovett M, Gilliland DG: Fusion of PDGF receptor B to a novel ETS-like gene, TEL, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 77:307, 1994
6. Papadopoulos P, Ridge SA, Boucher CA, Stocking C, Wiederman LM: The novel activation of ABL by fusion to an ets-related gene TEL. Cancer Res 55:34, 1995
7. Golub TR, Barker GF, Bohlander SK, Heibert SC, Ward DC, Bray-Ward P, Morgan E, Raimondi SC, Rowley JD, Gilliland DG: Fusion of the TEL gene on 12p13 to the AMLI gene on 21q22 in acute lymphoblastic leukemia. Proc Natl Acad Sci USA 92:4917, 1995
8. Romana SP, Mauchaffé M, Le Coniat M, Chumakov I, Le Paslier D, Berger R, Bernard OA: The t(12;21) of acute lymphoblastic leukemia results in a TEL-AML1 gene fusion. Blood 85:3662, 1995
9. Lekanne Deprez RH, Riegman PH, Groen NA, Warringa UL, van Biezen NA, Molijn AC, Bootsma D, de Jong PJ, Menon AG, Kley NA, Seizinger BR, Zwarthoff EC: Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma. Oncogene 10:1521, 1995
10. Buijs A, Sherr S, van Baal S, van Bezouw S, ven der Plas D, Guerts van Kessel A, Riegman P, Lekanne Deprez R, Zwarthoff E, Hagemeijer A, Grosveld G: Translocation (12;22)(p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. Oncogene 10:1511, 1995
11. Wlodarska I, Mecucci C, Marynen P, Guo C, Franckx D, La Strza R, Aventin A, Bosly A, Martelli MF, Cassiman JJ, Van den Berghe H: TEL gene is involved in myelodysplastic syndromes with either the typical t(5; 12)(q33;p13) translocation or its variant t(10; 12)(q24;p13). Blood 85:2848, 1995
12. Kobayashi H, Montgomery K, Bohlander S, Adra C, Lim B, Kucherlapati R, Donis-Keller H, Holt M, Le Beau M, Rowley JD: Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases. Blood 84:3473, 1994
13. Kobayashi H, Rowley JD: Identification of cytogenetically undetected 12p13 translocations and associated deletions with fluorescence in situ hybridization. Genes Chromosom Cancer 12:66, 1995
14. ISCN 1991: Cancer Cytogenetics, Supplement to an International System for Human Cytogenetic Nomenclature, vol VI. Basel, Switzerland, S. Karger AG, 1991
15. Höglund M, Åman P, Mandahl N, Lehrach H, Mitelman F: Isolation and regional localization of cosmid linking clones from human chromosome 12. Genomics 21:583, 1994
16. Chaffanet M, Beans M, Aerssens J, Schoenmakers E, Cassiman J-J, Marynen P: Mapping of an ordered set of 14 cosmids to human chromosome 12p by two-color in situ hybridization. Cytogenet Cell Genet 69:27, 1995
17. Wlodarska I, Mecucci C, Marynen P, Guo C, Frankckx D, La Starza R, Aventin A, Bosly MF, Martelli JJ, Cassiman JJ, Van Den Berghe H. TEL gene is involved in myelodysplastic syndromes with either the typical t(5; 12)(q33;p13) or its variant t(10; 12)(q24;p13) Blood 85:2848, 1995
18. Xiong Y, Menninger J, Beach D, Ward DC: Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins. Genomics 13:575, 1992
19. Montgomery KT, LeBlanc JM, Tsal P, McNich JS, Ward DC, de Jong PJ, Kucherlapati R, Krauter KS: Characterization of two chromosome 12 cosmid libraries and development of STSs from cosmids mapped by FISH. Genomics 17:682, 1993
20. Baens M, Aerssens J, Van Zand K, Cassiman JJ, Van Den Berghe H, Marynen P: Isolation and regional assignment of human chromosome 12p cDNAs. Genomics 29:44, 1995
21. Höglund M, Sidén T, Åman P, Mandahl N, Mitelman F: Isolation and characterization of radiation hybrids for human chromosome 12. Cytogenet Cell Genet 69:240, 1995
22. Sahlin P, Mark J, Stenman G: Submicroscopic deletions of 3p sequences in pleomorphic adenomas with t(3;8)(p21;q12). Genes Chromosom Cancer 10:256, 1994
23. Diaz MO, Rubin CM, Harden A, Zeimin S, Larson R, Le Beau MM, Rowley J: Deletions of interferon genes in acute lymphoblastic leukemia. N Engl J Med 322:77, 1990
24. Adra CN, Kobayashi H, Rowley JD, Lim B: Assignment of the human GDID4 gene, GDP/GTP-exchange regulator, to chromosome 12p12.3. Genomics 24:188, 1994
25. Pietenpol JA, Bohlander SK, Sato Y, Papadopoulos N, Liu B, Friedman C, Trask B, Roberts JM, Kinzler K, Rowley JD, Vogelstein B: Assignment of the human p27kip1 gene to 12p13 and its analysis in leukemias. Cancer Res 55:1206, 1995
26. Bullrich F, MacLachlan TK, Sang N, Druck T, Veronese ML, Allen SL, Chiorazzi N, Koff A, Heubner K, Croce CM, Giordano A: Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and cdk inhibitor, p27kip1, to regions involved in human cancer. Cancer Res 55:1199, 1995
27. Ponce-Castaneda MV, Lee M-H, Latres E, Polyak K, Lacombe L, Montgomery K, Mathew S, Krauter K, Sheinfeld J, Massague J, Cordon-Cardo C: p27Kip1: Chromosomal mapping to 12p12-12p13 1 and absence of mutations in human tumors. Cancer Res 55:1211, 1995
28. Sherr CJ: G1 phase progression: Cycling on cue. Cell 79:551, 1994
29. Toyoshima H, Hunter T: p27, a novel inhibitor of G1 cyclinCdk protein kinase activity, is related to p21. Cell 78:67, 1994
30. Stegmaier K, Pendse S, Barker GF, Bray-Ward P, Ward DC, Montgomery KT, Krauter KS, Reynolds C, Sklar J, Donnelly M, Bohlander SK, Rowley JD, Sallan SE, Gilliland DG, Golub TR: Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood. Blood 86:38, 1995
31. Palmero I, Holder A, Sinclair AJ, Dickson C, Peters G: Cyclins D1 and D2 are differentially expressed in human B-lymphoid cell lines. Oncogene 8:1049, 1993
32. Leach FS, Elledge SJ, Sherr CJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B: Amplification of cyclin genes in colorectal carcinomas. Cancer Res 53:1986, 1993
33. Lammie GA, Fantl V, Smith R, Schuuring E, Brookes S, Michalides R, Dickson C, Arnold A, Peters G: D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1. Oncogene 6:439, 1991
34. Withers D, Harvey R, Faust J, Melnyk O, Carey K, Meeker T: Characterization of a candidate bcl-1 gene. Mol Cell Biol 11:4846, 1991
35. Motokura T, Arnold A: PRAD1/cyclin D1 proto-oncogene: Genomic organization, 5′ DNA sequence, and sequence of a tumor-specific rearrangement breakpoint. Genes Chromosom Cancer 7:89, 1993
36. Billström R, Thiede T, Hansen S, Heim S, Kristoffersson U, Mandahl N, Mitelman F: Bone marrow karyotype and prognosis in primary myelodysplastic syndromes. Eur J Haematol 41:341, 1988
37. Heim S, Békàssy AN, Garwicz S, Heldrup J, Kristoffersson U, Mandahl N, Wiebe T, Mitelman F: Bone marrow karyotypes in 94 children with acute leukemia. Eur J Haematol 41:227, 1989
38. Johansson B, Mertens F, Heim S, Kristoffersson U, Mandahl N, Nilsson PG, Mitelman F: Cytogenetic findings in acute megakaryoblastic leukemia (ANLL-M/). Cancer Genet Cytogenet 48:119, 1990