A single-center population-based consecutive series of 1500 cytogenetically investigated adult hematological malignancies: Karyotypic features in relation to morphology, age and gender

European Journal of Haematology

Volumn 62, Issue 2, 1999, Pages 95-102

  Mauritzson, Nils ^a   Johansson, B ^a   Albin, M ^a   Billstrom R ^a   Ahlgren, T ^b   Mikoczy, Z ^a   Nilsson, P G ^a   Hagmar, L ^a   Mitelman, F ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b MALMÖ UNIVERSITY   (Sweden)

Author keywords

Age; Chromosomes; Gender; Leukemia; Morphology

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; AGING; ARTICLE; CHRONIC MYELOID LEUKEMIA; CYTOGENETICS; FEMALE; HUMAN; HUMAN CELL; KARYOTYPE; LEUKEMIA; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL;

EID: 0032939412     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1999.tb01728.x     Document Type: Article

References (50)

1. HEIM S, MITTELMAN F. Cancer cytogenetics, 2nd edn. New York: Wiley-Liss, 1995.
2. RABBITTS TH. Chromosomal translocations in human cancer. Nature 1994;372:143-149.
3. MITELMAN F, MERTENS F, JOHANSSON B. A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet 1997;15:417-474.
4. DREXLER HG, MACLEOD RAF, BORKHARDT A, JANSSEN JWG. Recurrent chromosomal translocations and fusion genes in leukemia-lymphoma cell lines. Leukemia 1995;9:480-500.
5. MITELMAN F. Catalog of chromosome aberrations in cancer, 6th edn. New York: Wiley-Liss 1998:(in press).
6. PEDERSEN-BJERGAARD J, ROWLEY JD. The balanced and the unbalanced chromosome aberrations of acute myeloid leukemia may develop in different ways and may contribute differently to malignant transformation. Blood 1994;83:2780-2786.
7. APLAN PD, CHERVINSKY DS, STANULLA M, BURHANS WC. Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors. Blood 1996;87:2649-2658.
8. FOURTH INTERNATIONAL WORKSHOP ON CHROMOSOMES IN LEUKEMIA. Overview of association between chromosome pattern and cell morphology, age, sex, and race. Cancer Genet Cytogenet 1984;11:265-274.
9. FOURTH INTERNATIONAL WORKSHOP ON CHOROMOSOMES IN LEUKEMIA. Correlation between morphology and karyo-type. Cancer Genet Cytogenet 1984;11:275-281.
10. KNAPP RH, DEWALD GW, PIERRE RV. Cytogenetic studies in 174 patients with preleukemic or myelodysplastic syndromes. Mayo Clin Proc 1985;60:507-516.
11. BERGER R, FLANDRIN G, BERNHEIM A, et al. Cytogenetic studies on 519 consecutive de novo acute nonlymphocytic leukemias. Cancer Genet Cytogenet 1987;29:9-21.
12. OLOPADE OI, THANGAVELU M, LARSON RA, et al. Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia. Blood 1992;80:2873-2882.
13. TOYAMA K, OUYASHIKI K, YOSHIDA Y, et al. Clinical implications of chromosomal abnormalities in 401 patients with MDS: a multicentric study in Japan. Leukemia 1993;7:499-508.
14. HAASE D, FONATSCH C, FREUND M, et al. Cytogenetic findings in 179 patients with myelodysplastic syndromes. Ann Hematol 1995;70:171-187.
15. HOFF PM, PIERCE S, ESTEY E. Comparison of acute myeloid leukemia patients at MD Anderson: 1982-1986 vs 1992-1996. Leukemia 1997;11:1997-1998.
16. CASASNOVAS RO, CAMPOS L, MUGNERET F, et al. Immunophenotypic patterns and cytogenetic anomalies in acute non-lymphoblastic leukemia subtypes: a prospective study of 432 patients. Leukemia 1998;12:34-43.
17. BENNETT JM, CATOVSKY D, DANIEL MT, et al. Proposals for the classification of the acute leukaemias. Br J Haematol 1976;33:451-458.
18. BENNETT JM, CATOVSKY D, DANIEL MT, et al. The French-American-British (FAB) Co-operative Group: proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982;51:189-199.
19. BENNETT JM, CATOVSKY D, DANIEL M-T, et al. Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). Ann Int Med 1985;103:460-462.
20. BENNETT JM, CATOVSKY D, DANIEL MT, et al. A report of the French-American-British Cooperative Group: proposed revised criteria for the classification of acute myeloid leukemia. Ann Int Med 1985;103:626-629.
21. BENNETT JM, CATOVSKY D, DANIEL MT, et al. Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-M0). Br J Haematol 1991;78:325-329.
22. ÖST Å, REIZENSTEIN P. Minimal diagnostic criteria for the myelodysplastic syndrome. Leuk Res 1992;16:9-11.
23. BENNETT JM, CATOVSKY D, DANIEL MT, et al. The chronic myeloid leukaemias: guidelines for distinguishing chronic granulocytic, atypical chronic myeloid, and chronic myelomonocytic leukaemia. Proposals by the French-American-British Cooperative Leukaemia Group. Br J Haematol 1994;87:746-754.
24. MITELMAN F, ED. ISCN: an international system for human cytogenetic nomenclature. Basel: Karger 1995.
25. BILLSTRÖM R, NILSSON P-G, MITELMAN F. Cytogenetic analysis in 941 consecutive patients with haematologic disorders. Scand J Haematol 1986;37:29-40.
26. PERKINS D, BRENNAN S, CARSTAIRS K, et al. Regional cancer cytogenetics: a report on 1,143 diagnostic cases. Cancer Genet Cytogenet 1997;96:64-80.
27. LI YS, HAYHOE FGJ. Cytogenetic studies in acute myeloid leukemia using peripheral blood samples sent by post. J Clin Pathol 1982;35:861-865.
28. CZEPULKOWSKI BH, BHATT B, ROONEY DE. Basic techniques for the preparation and analysis of chromosomes from bone marrow and leukaemic blood In: ROONEY DE, CZEPULKOWSKI BH, eds. Human cytogenetics: a practical approach, vol II: Malignancy and acquired abnormalities, 2nd edn, vol 2. Oxford: Oxford University Press, 1992:1-25.
29. WILLIAMS DL, HARRIS A, WILLIAMS KJ, BROSIUS MJ, LEMONDS W. A direct bone marrow chromosome technique for acute lymphoblastic leukemia. Cancer Genet Cytogenet 1984;13:239-257.
30. BUCKLE VJ, KEARNY L. New methods in cytogenetics. Curr Opin Genet Dev 1994;4:374-382.
31. BENTZ M, DÖHNER H, CABOT G, LICHTER P. Fluorescence in situ hybridization in leukemias: "The FISH are spawning!". Leukemia 1994;8:1447-1452.
32. VELDMAN T, VIGNON C, SCHRÖCK E, ROWLEY JD, RIED T. Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping. Nat Genet 1997;15:406-410.
33. MILLER KB. Clinical manifestations of acute myeloid leukemia In: HOFFMAN R, BENZ JR EJ, SHATTIL SJ, FURIE B, COHEN HJ, SILBERSTEIN LE, eds. Hematology: basic principles and practice, 2nd edn. New York: Churchill Livingstone, 1995:993-1014.
34. DUNBAR CE, NIENHUIS AW. Myelodysplastic syndromes In: HANDIN RI, LUX SE, STOSSEL TP, eds. Blood: principles and practice of hematology. Philadelphia: J.B. Lippincott Company, 1995:377-414.
35. BERGER R, LE CONIAT M, DERRÉ J, VECCHIONE D, JONVEAUX P. Cytogenetic studies in acute promyelocytic leukemia: a survey of secondary chromosomal abnormalities. Genes Chromosomes Cancer 1991;3:332-337.
36. HIORNS LR, SWANSBURY GJ, MEHTA J, et al. Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukemia. Br J Haematol 1997;96:314-321.
37. FENAUX P, MOREL P, LAI JL. Cytogenetics of myelodysplastic syndromes. Semin Hematol 1996;33:127-138.
38. BERGER R, FLANDRIN G. Chromosomal abnormalities in secondary acute myeloid leukaemia and the myelodysplastic syndromes In: MUFTI GJ, GALTON DAG, eds. The myelodysplastic syndromes. Edinburgh: Churchill Livingstone, 1992:129-139.
39. BENNETT JM. FAB and MIC classification of myelodysplastic syndromes: points of controversy In: MUFTI GJ, GALTON DAG, eds. The myelodysplastic syndromes. Edinburgh: Churchill Livingstone, 1992:15-21.
40. LI Y-S, KHALID G, HAYHOE FGJ. Correlation between chromosomal pattern, cytological subtypes, response to therapy, and survival in acute myeloid leukemia. Scand J Haematol 1983;30:265-277.
41. LI Y-S. Correlation of karyotype with patient sex and age in acute myeloid leukemia. Cancer Genet Cytogenet 1985;14:73-81.
42. RODELLA S, CICCONE G, REGE-CAMBRIN G, VINEIS P. Cytogenetics and occupational exposures in acute nonlymphocytic leukemia and myelodysplastic syndrome. Scand J Work Environ Health 1993;19:369-374.
43. MERTENS F, JOHANSSON B, MITELMAN F. Age- and gender-related heterogeneity of cancer chromosome aberrations. Cancer Genet Cytogenet 1993;70:6-11.
44. BOULTWOOD J, LEWlS S, WAINSCOAT JS. The 5q- syndrome. Blood 1994;84:3253-3260.
45. PIERRE RV, CATOVSKY D, MUFTI GJ, et al. Clinical-cytogenetic correlations in myelodysplasia (preleukemia). Cancer Genet Cytogenet 1989;40:149-161.
46. MICHALOVA K, MUSILOVA J, ZEMANOVA Z. Consecutive chromosomal studies in patients with myelodysplastic syndrome (MDS). Czechoslovak MDS Cooperative group. Ann Genet 1991;34:212-218.
47. MOREL P, HEBBAR M, LAI J-L, et al. Cytogenetic analysis has strong independent prognostic value in de novo myelodys-plastic syndromes and can be incorporated in a new scoring system: a report on 408 cases. Leukemia 1993;7:1315-1323.
48. WONG KF, HAYES KJ, LEUNG S, GLASSMAN AB. The relationship between age and karyotypic abnormalities in myelodysplastic syndromes. Cancer Genet Cytogenet 1996;88:80-82.
49. THE SWEDISH CANCER REGISTRY. Cancer Incidence in Sweden 1990. Stockholm: The National Board of Health and Welfare, 1993.
50. LEITH CP, KOPECKY KJ, GODWIN J, et al. Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study. Blood 1997;89:3323-3329.