Localized adenovirus gene delivery using antiviral IgG complexation

Gene Therapy

Volumn 8, Issue 9, 2001, Pages 659-667

  Levy, R J ^a   Song, C ^a   Tallapragada, S ^a   DeFelice, S ^a   Travis Hinson, J ^a   Vyavahare, N ^a   Connolly, J ^a   Ryan, K ^a   Li, Q ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Antibody mediated; Local delivery; Site specific

Indexed keywords

AVIDIN; BETA GALACTOSIDASE; COLLAGEN TYPE 1; GANCICLOVIR; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN G; NEUTRAVIDIN; POLYCLONAL ANTIBODY; THYMIDINE KINASE; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS VECTOR; VITROGEN 100;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; AORTA MEDIA; ARTICLE; BIOTINYLATION; CELL CONTACT; CELL CULTURE; CELL DEATH; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCATION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HEART RIGHT VENTRICLE; HERPES SIMPLEX; IMMOBILIZATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPORTER GENE; SMOOTH MUSCLE FIBER; SWINE; VIRION;

ADENOVIRIDAE; ANIMALS; ANTIBODIES, VIRAL; ANTIGEN-ANTIBODY COMPLEX; AORTA; BIOTINYLATION; CELL CULTURE TECHNIQUES; CELL DEATH; COLLAGEN; GANCICLOVIR; GELS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; IMMUNOGLOBULIN G; MUSCLE, SMOOTH, VASCULAR; RATS; SWINE; TRANSDUCTION, GENETIC;

ADENOVIRIDAE; ANIMALIA; DNA VIRUSES; HERPES; SUS SCROFA;

EID: 0034991288     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301452     Document Type: Article

References (36)

1. Gene therapy for lung cancer: Enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer
2. Adenovirus infection in cystic fibrosis patients: Implications for the use of adenoviral vectors for gene transfer
3. Developing adenoviral-mediated in vivo gene therapy for ornithine transcarbamylase deficiency
4. Gene therapy for malignant pleural mesothelioma
5. Human gene therapy for hereditary diseases: A review of trials
6. In situ gene therapy for adenocarcinoma of the prostate: A phase I clinical trial
7. A phase I/II study of hepatic artery infusion with wtp53-CMV-Ad in metastatic malignant liver tumors
8. Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: Results of a phase 1 clinical trial
9. New methods of drug delivery
10. Drug delivery and targeting
11. Sustained delivery of proteins for novel therapeutic agents
12. Perivascular and intravenous administration of basic fibroblast growth factor: Vascular and solid organ deposition
13. Polymers for the sustained release of proteins and other macromolecules
14. Reversible hydrogels from self-assembling artificial proteins
15. Long-acting gonadatropin-releasing hormone implant to maintain medical castration for two years in men with prostate cancer
16. Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo
17. Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimal hyperplasia in a rat carotide artery injury model
18. Antisense oligonucleotide inhibition of PDGFR-beta receptor subunit expression directs suppression of intimal thickening
19. Pressure-mediated oligonucleotide transfection of rat and human cardiovascular tissues
20. Effects of antisense c-myb oligonucleotides on vascular smooth muscle cell proliferation and response to vessel wall injury
21. Localized direct plasmid gene delivery in vivo: Prolonged therapy results in reproducible tissue regeneration
22. A DNA controlled-release coating for gene transfer: Transfection in skeletal and cardiac muscle
23. Gene transfection using biodegradable nanospheres: Results in tissue culture and a rat osteotomy model
24. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
25. DNA delivery from polymer matrices for tissue engineering
26. Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo
27. Coacervate microspheres as carriers of recombinant adenoviruses
28. Enzymatic cleavage of disaccharide side groups in insoluble synthetic polymers: A new method for specific delivery of drugs to the colon
29. A versatile method for the conjugation of proteins and peptides to poly[2-(dimethylamino)ethyl methacrylate]
30. Antibody tethered adenovirus for stent-based vector delivery in pig coronaries
31. Bystander effect of purine nucleoside analogues in HSV-1 tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues
32. Cancer gene therapy with HSV-tk/GCV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo
33. In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene
34. Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery
35. FGF2-targeted adenovirus encoding platelet derived growth factor-B enhances de noco tissue formation
36. Uses of fusions of beta-galactosidase and peptides to proteins