Stable recombinant expression and characterization of the two haemophilic factor VIII variants C329s (CRM-) and G1948D (CRMr)

British Journal of Haematology

Volumn 113, Issue 3, 2001, Pages 604-615

  David, Dezsö ^a   Saenko, Evgueni L ^b   Santos, I M Ana ^a   Johnson, Daniel J D ^c   Tuddenham, Edward G D ^c   McVey, John H ^c   Kemball Cook, Geoffrey ^c  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b AMERICAN RED CROSS   (United States)

^c MRC CLINICAL SCIENCES CENTRE   (United Kingdom)

Author keywords

Expression; Factor VIII; Haemophilia; Immunofluorescence; Recombinant

Indexed keywords

BLOOD CLOTTING FACTOR 8; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CHO CELL; GENE MUTATION; HEMOPHILIA A; IMMUNOBLOTTING; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING; RNA TRANSCRIPTION; SITE DIRECTED MUTAGENESIS; SURFACE PLASMON RESONANCE;

ANIMALS; BIOSENSING TECHNIQUES; CHO CELLS; CRICETINAE; FACTOR VIII; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HEMOPHILIA A; HUMANS; IMMUNOBLOTTING; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PHENOTYPE; REGRESSION ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THROMBIN; TRANSGENES;

EID: 0034988758     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02399.x     Document Type: Article

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