Does treatment at the time of locoregional failure of breast cancer alter prognosis?

Cancer Treatment Reviews

Volumn 27, Issue 2, 2001, Pages 83-97

  Clemons, M ^b   Hamilton, T ^a   Goss, P ^a  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

Breast cancer; Locoregional recurrence

Indexed keywords

CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; MEGESTROL ACETATE; PLACEBO; TAMOXIFEN; VINCRISTINE;

AXILLARY LYMPH NODE; BREAST CANCER; CANCER HORMONE THERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LYMPH NODE DISSECTION; MASTECTOMY; MEDICAL DECISION MAKING; METASTASIS; PROGNOSIS; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; REVIEW; TREATMENT FAILURE;

EID: 0034986391     PISSN: 03057372     EISSN: None     Source Type: Journal    
DOI: 10.1053/ctrv.2001.0205     Document Type: Review

References (218)

1. Local-regional breast cancer recurrence following mastectomy
2. Subsequent sites of recurrence in patients with local, regional and soft tissue relapse: An analysis on 1217 cases
3. Relapse of breast cancer after adjuvant treatment in premenopausal and perimenopausal women: Patterns and prognoses
4. Effect of systemic adjuvant treatment on first sites of breast cancer relapse
5. Long-term follow-up of axillary node-positive breast cancer patients receiving adjuvant systemic therapy alone: Patterns of recurrence
6. Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer
7. Significance of ipsilateral breast tumour recurrence after lumpectomy
8. Ipsilateral breast tumour recurrence and survival following lumpectomy and irradiation: Pathological findings from NSABP protocol B-06
9. Locoregional recurrences after 649 modified radical mastectomies: Incidence and significance
10. Local or regionally recurrent carcinoma of the breast: Results of therapy in 121 patients
11. Local recurrences in patients with breast cancer at the North Carolina Memorial Hospital (1970-1982)
12. Local-regional recurrence after mastectomy or breast conserving therapy
13. Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation: Experience of the Eastern Cooperative Oncology Group
14. Prognosis following local or regional recurrence after conservative surgery and radiotherapy for early stage breast carcinoma
15. Breast recurrence following conservative surgery and radiation: Patterns of failure, prognosis, and pathologic findings from mastectomy specimens with implications for treatment
16. Breast cancer. Experiences with conservation therapy
17. Local recurrence after breast-conserving surgery and radiotherapy. Frequency, time course, and prognosis
18. Postmastectomy radiotherapy: Randomized trials
19. Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial
20. Radiotherapy after breast-preserving surgery in women with localized cancer of the breast
21. Sector resection with or without postoperative radiotherapy for stage I breast cancer: Five-year results of a randomized trial
22. Breast tumor recurrence following lumpectomy with and without breast irradiation: An overview of recent NSABP findings
23. Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation
24. Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: An update
25. Randomized clinical trial to assess the effectiveness of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer
26. The clinical significance of skin recurrence after radical mastectomy in women with cancer of the breast
27. Survival following locoregional recurrence of breast cancer: Univariate and multivariate analysis
28. Survival following breast-conserving surgery and irradiation or modified radical mastectomy in patients with invasive breast cancer with a maximum diameter of 1 cm
29. Regional nodal management and patterns of failure following conservative surgery and radiation therapy for stage I and II breast cancer
30. Pattern of dissemination and survival following isolated locoregional recurrence of breast cancer. A prospective study with more than 10 years of follow up
31. Survival and pattern of failure following locoregional recurrence of breast cancer
32. The results of radiation therapy for isolated local regional recurrence after mastectomy
33. Annual hazard rates of recurrence for breast cancer after primary therapy
34. Natural history and prognosis of recurrent breast cancer
35. Improved methodology for analyzing local and distant recurrence
36. Alternative approaches to evaluating the impact of local control on survival
37. Editorial comment on the link between local recurrence and distant metastasis in human breast cancer by Serge Koscienly and Maurice Tubiana
38. Natural history of human breast cancer: Recent data and clinical implications
39. The link between local recurrence and distant metastases in human breast cancer
40. The natural history of human breast cancer. The relationship between involvement of axillary lymph nodes and the initiation of distant metastases
41. Breast cancer: Relationship between the size of the primary tumour and the probability of metastatic dissemination
42. Post-mastectomy megavoltage radiotherapy: The Oslo and Stockholm trials
43. Adjuvant radiotherapy in operable breast cancer: Correlation between dose in internal mammary nodes and prognosis
44. Radiation therapy in operable breast cancer: Results from the Stockholm trial on adjuvant radiotherapy
45. Does locoregional radiation therapy improve survival in breast cancer? A meta-analysis
46. Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial
47. Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy
48. Adjuvant radiotherapy and chemotherapy in node-positive premenopausal women with breast cancer
49. Adequate locoregional treatment for early breast cancer may prevent secondary dissemination
50. Prognostic significance of breast relapse after conservative treatment in node-negative early breast cancer
51. Human cancer natural history, radiation induced immunodepression and post-operative radiation therapy
52. Ipsilateral breast tumor recurrence following breast-conserving surgery for early-stage invasive cancer
53. Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: Results from a randomized trial
54. The prognostic significance of late local recurrence after breast-conserving therapy
55. Locally recurrent carcinoma of the breast. Results of radiation therapy
56. Full thickness chest wall resection for recurrent breast carcinoma involving the bony chest wall
57. Factors associated with local breast cancer recurrence after lumpectomy alone
58. Late breast recurrence after lumpectomy and irradiation
59. Chest wall resection in the treatment of local recurrence of breast cancer
60. Reoperation for locally recurrent breast cancer in patients previously treated with conservative surgery
61. The use of raditherapy for treatment of isolated locoregional recurrence of breast carcinoma after mastectomy
62. Local recurrence and distant metastases after breast-conserving surgery and radiation therapy for early breast cancer
63. Analysis of failures following local treatment of isolated local-regional recurrence of breast cancer
64. Analysis of prognostic factors in patients with isolated chest wall recurrence of breast cancer
65. Chest wall resection for locally recurrent breast cancer: Is it worthwhile?
66. Chest wall resection for locally recurrent breast cancer: Indications, technique, and results
67. Outcome of surgical resection for chest wall recurrence in breast cancer patients
68. Chest wall resection in the treatment of locally recurrent breast carcinoma: Indications and outcome for 44 patients
69. Combined modality approach in breast cancer with isolated or multiple metastases
70. Results of irradiation in the treatment of locoregional breast cancer recurrence
71. Management of locoregional recurrent breast cancer
72. Management of locally recurrent breast cancer
73. Isolated local-regional recurrence following mastectomy for adenocarcinoma of the breast treated with radiation therapy alone or combined with surgery and/or chemotherapy
74. The significance of local recurrence of carcinoma of the breast
75. Locoregional recurrence of breast cancer: A retrospective comparison of irradiation alone versus irradiation and systemic therapy
76. Locoregional recurrence of breast cancer following mastectomy: Always a fatal event? Results of univariate and multivariate analysis
77. Prognostic indicators in patients with isolated local-regional recurrence of breast cancer
78. Prognosticators in recurrent breast cancer. A 15-year experience with irradiation
79. Treatment of locally recurrent breast carcinoma
80. Locoregional first recurrence after mastectomy: Prospective cohort studies with and without immediate chemotherapy
81. A biostatistical study of locally recurrent breast carcinoma
82. Ointments with 5-fluorouracille, used in care of patients with breast exulcerative cancers
83. Miltefosine 6% solution (MIL) as a local treatment in cutaneous metastases of breast cancer in patients receiving a concomitant systemic therapy: Preliminary results
84. An evaluation of photodynamic therapy in the management of cutaneou metastases of breast cancer
85. Recurrence in the conserved breast: Why all this fuss about risk factors?
86. Locoregional recurrence following radical external beam irradiation and interstitial implantation for operable breast cancer-a twenty three year experience
87. Is breast conservation after local recurrence feasible?
88. Prognosis following salvage mastectomy for recurrence in the breast after conservative surgery and radiation therapy for early-stage breast cancer
89. Conservation therapy for breast cancers other than infiltrating ductal carcinoma
90. Salvage mastectomy for local and regional recurrence after breast-conserving operation and radiation therapy
91. Survival following locoregional recurrence after breast conservation therapy for cancer
92. Outcome of treatment for ipsilateral breast tumor recurrence in earlystage breast cancer
93. Analysis of local-regional relapses in patients with early breast cancers treated by excision and radiotherapy: Experience of the Institut Gustave-Roussy
94. Ipsilateral breast tumor recurrence as a predictor of distant disease: Implications for systemic therapy at the time of local relapse
95. Survival from first recurrence: Relative importance of prognostic factors in 1.015 breast cancer patients
96. Total mastectomy is not always mandatory for the treatment of recurrent breast cancer after lumpectomy alone
97. Polychemotherapy for early breast cancer: An overview of the randomised trials
98. Tamoxifen for early breast cancer: An overview of the randomised trials
99. Combined modality therapy for first recurrence of breast cancer: A Southwest Oncology Group study
100. First isolated locoregional recurrence following mastectomy for breast cancer: Results of a phase III multicenter study comparing systemic treatment with observation after excision and radiation
101. Management of locoregional recurrent breast cancer
102. Results of salvage surgery for mammary recurrence following breast-conserving therapy
103. Results of wide excision for mammary recurrence after breast-conserving therapy
104. Local recurrence after breast-conserving surgery and radiotherapy. Frequency, time course, and prognosis
105. High dose chemotherapy and autologous blood stem cell support in women with breast carcinoma and isolated supraclavicular lymph node metastases
106. Local-regional treatment of patients with simultaneous local-regional recurrence and distant metastases following mastectomy
107. Breast conservation: Predictors and treatment of local recurrence
108. Adjuvant chemotherapy with fluorouracil, doxorubicin, and cyclophosphamide, with or without Bacillus Calmette Guerin and with or without irradiation in operable breast cancer. A prospective randomized trial
109. Supraclavicular lymph node metastases (SLM) from breast cancer as only site of distant disease: Has radiotherapy any role?
110. Ten-year experience with CMG-based chemotherapy in resectable breast cancer
111. Radiation therapy for local-regional recurrent breast carcinoma
112. Review of local soft tissue recurrence of breast cancer irradiated with and without actinomycin-D
113. Adjuvant chemoimmunotherapy following regional therapy for isolated recurrences of breast cancer (stage IV NED)
114. Extended survival in 80 patients with operable, locoregionally recurrent breast cancer treated with chemotherapy
115. Recurrent breast cancer: Factors influencing survival, including treatment
116. The significance of local recurrence of carcinoma of the breast
117. Wide local excision of recurrent breast cancer in the thoracic wall
118. The implications of local recurrence of breast cancer as the first site of therapeutic failure
119. Adjuvant radiation therapy versus surgery alone in operable breast cancer: Long-term follow-up of a randomized clinical trial
120. Local recurrences and distant metastases after breast-conserving surgery and radiation therapy for early breast cancer
121. Management of locally recurrent breast cancer
122. Systemic treatment for locoregional relapse of breast cancer: What do European Oncologists recommend?
123. Management of recurrent locoregional breast cancer
124. Predicting the rate and extent of locoregional failure after breast conservation therapy for early breast cancer
125. Local failure and margin status in early-stage breast carcinoma treated with conservation surgery and radiation therapy
126. Conservative treatment versus mastectomy in early breast cancer: Patterns of failure with 15 years of follow-up data
127. Uncontrolled local recurrence after treatment of breast cancer with breast conservation
128. Danish randomized trial comparing breast conservation therapy with mastectomy: Six years of life-table analysis
129. Risk factors in breast-conservation therapy
130. Factors associated with local recurrence as a first site of failure following the conservative treatment of early breast cancer
131. Results of salvage mastectomy for local recurrence after breast-conserving surgery without radiation therapy
132. Breast conservation therapy for invasive breast cancer in Hong Kong: Factors affecting recurrence and survival in Chinese women
133. Breast cancer: A 21 year experience with conservative surgery and radiation
134. Survival from first recurrence: Relative importance of prognostic factors in 1,015 breast cancer patients
135. Tamoxifen with and without radiation after partial mastectomy in patients with involved nodes
136. Local and distant recurrence after conservative management of very low-risk breast cancer are dependent events: A 10-year follow-up
137. Factors influencing local recurrence of cancer after partial mastectomy
138. Local relapse and contralateral tumor rates in patients with breast cancer treated with conservative surgery and radiotherapy (Institut Gustave Roussy 1970-1982)
139. High local recurrence risk after breast-conserving therapy in node-negative premenopausal breast cancer patients is greatly reduced by one course of perioperative chemotherapy
140. Long-term follow-up of axillary node-positive breast cancer patients receiving adjuvant tamoxifen alone: Patterns of recurrence
141. Ten-year results from the National Surgical Adjuvant Breast and Bowel Project (NSABP) clinical trial evaluating the use of L-phenylalanine mustard (L-PAM) in the management of primary breast cancer
142. Prognostic factors of breast recurrence in the conservative management of early breast cancer: A 25-year follow-up
143. Skin recurrences after breast-conserving therapy for early-stage breast cancer
144. Quadrantic excision and axillary node dissection without radiation therapy: The long-term results of a selective policy in the treatment of stage I breast cancer
145. An analysis of age and family history on outcome after breast-conservation treatment: The University of Pennsylvania experience
146. Is breast-conserving surgery with radiation superior to mastectomy in selected patients?
147. Time course and prognosis of local recurrence following primary radiation therapy for early breast cancer
148. Local recurrence in the conservatively treated breast cancer patient: A correlation with age and family history
149. Should multicentric disease be an absolute contraindication to the use of breast-conserving therapy?
150. The significance of local control in the primary treatment of breast cancer. Lucy Wortham James clinical research award
151. Partial mastectomy without radiation therapy
152. Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer
153. Mammographic, pathologic, and treatment-related factors associated with local recurrence in patients with early-stage breast cancer treated with breast conserving therapy
154. Breast conservation treatment of early stage breast cancer: Patterns of failure
155. ctors influencing local recurrence after excision and radiotherapy for primary breast cancer
156. Prognostic implications of age in breast cancer patients treated with tumorectomy and irradiation or with mastectomy
157. Segmental mastectomy without radiotherapy for T1 and small T2 breast carcinomas
158. Salvage radiotherapy for local failures of lumpectomy and breast irradiation
159. Factors affecting recurrence in lumpectomy without irradiation for breast cancer
160. Eight-year results of a prospective non-randomised study on therapy of small breast cancer
161. Isolated axillary recurrences after conservative treatment of breast cancer
162. Pathological factors predictive of local recurrence in patients with invasive breast cancer treated by conservative surgery and radiation therapy
163. Rgin status and local recurrence after breast-conserving surgery
164. Results of the National Cancer Institute early breast cancer trial
165. Factors influencing local relapse and survival and results of salvage treatment after breast-conserving therapy in operable breast cancer: EORTC trial 10801, breast conservation compared with mastectomy in TNM breast cancer
166. Local control of operable breast cancer after radiotherapy alone
167. Local recurrences and distant metastases after conservative breast cancer treatments: Partly independent events
168. Oestrogen receptor status predicts local recurrence following breast conservation surgery for early breast cancer
169. Local recurrence after breast conservation therapy for early stage breast carcinoma: Detection, treatment, and outcome in 266 patients
170. A preliminary assessment of factors associated with recurrent disease in a surgical adjuvant clinical trial for patients with breast cancer with special emphasis on the aggressiveness of therapy
171. The effect of adjuvant radiotherapy on the time of occurrence and prognosis of local recurrence in primary operable breast cancer
172. Low risk of locoregional recurrence of primary breast carcinoma after treatment with a modification of the Halsted radical mastectomy and selective use of radiotherapy
173. Loco-regional recurrence following mastectomy for early breast carcinoma: Efficacy of radiotherapy at the time of recurrence
174. Local recurrence in breast cancer: Implications for systemic disease
175. Locally recurrent breast carcinoma: The effect of adjuvant chemotherapy on prognosis
176. The influence of untreated internal mammary metastases upon the course of mammary cancer
177. Long-range results for breast cancer patients treated by radical mastectomy and postoperative radiation without adjuvant chemotherapy: An update
178. Identification of a subgroup of patients with breast cancer and histologically positive axillary nodes receiving adjuvant chemotherapy who may benefit from postoperative radiotherapy
179. A close or positive margin after mastectomy is not an indication for chest wall irradiation except in women aged fifty or younger
180. Adjuvant chemo-endocrine therapy or endocrine therapy alone for postmenopausal patients: Ludwig Studies III and IV
181. Costs and benefits of adjuvant therapy in breast cancer: A quality-adjusted survival analysis
182. Locally recurrent breast cancer after 'radical' surgery
183. The 5-year results of a randomized trial of adjuvant radiation therapy after chemotherapy in breast cancer patients treated with mastectomy
184. Significance of local recurrence after mastectomy for breast cancer
185. Postoperative radiotherapy in breast cancer-long-term results from the Oslo study
186. Role of radiotherapy following total mastectomy in patients with early breast cancer
187. Chemo- or endocrine adjuvant therapy alone or combined in postmenopausal patients (GABG Trial 1)
188. Adjuvant postoperative radiotherapy, chemotherapy, and immunotherapy in stage III breast cancer. II. 5-year results and influence of levamisole
189. Radical mastectomy versus radical mastectomy plus internal mammary dissection. Five-year results of an international cooperative study
190. Is it useful to remove internal mammary nodes in operable breast cancer?
191. Predictors of recurrence for patients with small (one centimeter or less) localized breast cancer (T1a,b NO MO)
192. Randomised trial of chemo-endocrine therapy, endocrine therapy, and mastectomy alone in postmenopausal patients with operable breast cancer and axillary node metastasis
193. A randomized prospective trial of radical (Halsted) mastectomy versus modified radical mastectomy in 311 breast cancer patients
194. Primary breast cancer treatments: A locoregional recurrence review
195. Adjuvant radiotherapy and chemotherapy in breast cancer
196. Patterns of recurrence and relapse-Anglo-Japanese comparative study
197. West Midlands Oncology Association trials of adjuvant chemotherapy in operable breast cancer: Results after a median follow-up of 7 years. I. Patients with involved axillary lymph nodes
198. A randomized trial of chemotherapy (L-PAM vs CMF) and irradiation for node positive breast cancer. Eleven year follow-up of a Piedmont Oncology Association trial
199. Evaluation of radiotherapy in high-risk breast cancer patients: Report from the Danish Breast Cancer Cooperative Group (DBCG 82) Trial
200. Prognostic factors at presentation and their relevance to the natural history of breast cancer
201. Patterns of tumor relapse following mastectomy and adjuvant systemic therapy in patients with axillary lymph node-positive breast cancer. Impact of clinical, histopathologic, and flow cytometric factors
202. Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without tamoxifen without irradiation: Experience of the Eastern Cooperative Oncology Group
203. The efficacy of delayed radiotherapy for locoregionally recurrent postmastectomy breast cancer
204. Local-regional failure in patients treated with adjuvant chemotherapy for breast cancer
205. Locally recurrent cancer after radical mastectomy
206. Local-regional recurrence in breast cancer after mastectomy and adriamycin-based adjuvant chemotherapy: Evaluation of the role of postoperative radiotherapy
207. Elective irradiation with the electron beam after mastectomy for breast cancer
208. The total incidence of loco-regional recurrence in a randomized trial of breast cancer TNM stage II
209. A randomized trial of five and three drug chemotherapy and chemoimmunotherapy in women with operable node positive breast cancer
210. Adjuvant chemohormonal therapy with cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP) or CMFP plus tamoxifen compared with CMF for premenopausal breast cancer patients
211. The significance of recurrence in breast cancer
212. Long-term results of post-operative radiation therapy following mastectomy with or without chemotherapy in stage I-III breast cancer
213. Salvage treatment of patients suffering relapse after adjuvant CMF chemotherapy
214. Postsurgical adjuvant chemotherapy with or without radiotherapy in women with breast cancer and positive axillary nodes: A South-Eastern Cancer Study Group (SEG) Trial
215. Frequency, anatomical distribution and management of local recurrences after definitive therapy for breast cancer
216. A case-control study on risk factors for local recurrences or distant metastases in breast cancer patients treated with breast-conserving surgery
217. Characteristics of local recurrence following lumpectomy for breast cancer