A single amino acid alteration in the human parainfluenza virus type 3 hemagglutinin-neuraminidase glycoprotein confers resistance to the inhibitory effects of zanamivir on receptor binding and neuraminidase activity

Journal of Virology

Volumn 75, Issue 14, 2001, Pages 6310-6320

  Murrell, M T ^a   Porotto, M ^a   Greengard, O ^a   Poltoratskaia, N ^a   Moscona, A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; RECEPTOR; SIALIC ACID; VIRUS GLYCOPROTEIN; VIRUS HEMAGGLUTININ; VIRUS SIALIDASE; ZANAMIVIR;

ANIMAL CELL; ARTICLE; CERCOPITHECIDAE; CONTROLLED STUDY; DRUG RESISTANCE; ENZYME ACTIVITY; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NONHUMAN; PARAINFLUENZA VIRUS 3; PRIORITY JOURNAL; RECEPTOR BINDING; VIRUS INFECTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIVIRAL AGENTS; DRUG RESISTANCE, MICROBIAL; ENZYME INHIBITORS; GUANIDINES; HN PROTEIN; HUMANS; MOLECULAR SEQUENCE DATA; NEURAMINIDASE; PARAINFLUENZA VIRUS 3, HUMAN; POINT MUTATION; PROTEIN BINDING; PYRANS; RECEPTORS, CELL SURFACE; RECEPTORS, VIRUS; SEQUENCE ALIGNMENT; SIALIC ACIDS; ZANAMIVIR;

EID: 0034979362     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.14.6310-6320.2001     Document Type: Article

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