메뉴 건너뛰기




Volumn 28, Issue 3, 2001, Pages 260-273

Tamoxifen to raloxifene and beyond

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 METHYL 2 [4 [2 (1 PIPERIDINYL)ETHOXY]PHENYL] 7 PIVALOYLOXY 2H 1 BENZOPYRAN 3 YLPHENYL] PIVALATE; ACOLBIFENE; AMINOGLUTETHIMIDE; ANASTROZOLE; ANDROSTENEDIONE; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; ARZOXIFENE; DROLOXIFENE; EXEMESTANE; FORMESTANE; FULVESTRANT; IDOXIFENE; LETROZOLE; MEGESTROL ACETATE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR DOWNREGULATOR; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TOREMIFENE; UNCLASSIFIED DRUG;

EID: 0034979311     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/sonc.2001.23492     Document Type: Article
Times cited : (46)

References (119)
  • 2
    • 0032537396 scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomized trials
    • (1988) Lancet , vol.351 , pp. 1451-1467
  • 3
    • 0033575083 scopus 로고    scopus 로고
    • The effects of raloxifene on the risk of breast cancer in postmenopausal women: Results from the more randomized trial. Multiple outcomes of raloxifene evaluation
    • (1999) JAMA , vol.281 , pp. 2189-2197
    • Cummings, S.R.1    Eckert, S.2    Krueger, K.A.3
  • 6
    • 0029903614 scopus 로고    scopus 로고
    • Randomized trial of two versus five years of adjuvant tamoxifen for post-menopausal early stage breast cancer
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1543-1549
  • 7
    • 8044243594 scopus 로고    scopus 로고
    • Preliminary results from the Cancer Research Campaign trial evaluating tamoxifen duration in women aged fifty years or older with breast cancer
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1834-1839
  • 8
    • 0002339492 scopus 로고    scopus 로고
    • Prolonged follow-up of the Swedish randomized trial of two versus five years of adjuvant tamoxifen for postmenopausal early stage breast cancer and relationships to hormone receptor and ERB2 levels
    • abstr
    • (2000) Proc Am Soc Clin Oncol , vol.276 , pp. 72
    • Carstensen, J.1    Rutqvist, L.2    Stal, O.3
  • 11
    • 0001626384 scopus 로고
    • Antitumor activity of the antioestrogen ICI 46,474 (tamoxifen) in the dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma model
    • (1974) J Steroid Biochem , vol.5 , pp. 354
    • Jordan, V.C.1
  • 12
    • 0017078344 scopus 로고
    • Effects of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata
    • (1976) Eur J Cancer , vol.12 , pp. 419-424
    • Jordan, V.C.1
  • 14
    • 0018906517 scopus 로고
    • Evaluation of the anitumour activity of the nonsteroidal antioestrogen monohydroxytamoxifen in DMBA-induced rat mammary carcinoma model
    • (1980) Eur J Cancer , vol.16 , pp. 239-251
    • Jordan, V.C.1    Allen, K.E.2
  • 15
    • 0023229345 scopus 로고
    • The antitumor actions of keoxifene (raloxifene) and tamoxifen in the N-nitromethylurea-induced rat mammary carcinoma model
    • (1987) Cancer Res , vol.47 , pp. 4020-4924
    • Gottardis, M.M.1    Jordan, V.C.2
  • 22
  • 31
    • 0030033913 scopus 로고    scopus 로고
    • Antiatherogenic effects of adjuvant antiestrogens: A randomized trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in postmenopausal women with node-positive breast cancer
    • (1996) J Clin Oncol , vol.14 , pp. 429-433
    • Saarto, T.1    Blomquist, C.2    Ehnholm, C.3
  • 34
    • 0026557343 scopus 로고
    • Systemic therapy of early breast cancer by hormonal, cytotoxic and immune therapy: 133 Randomized trials involving 331,000 recurrances and 24,000 deaths among 75,000 women
    • (1992) Lancet , vol.339 , pp. 1-15
  • 35
    • 0027325734 scopus 로고
    • Cardiac and thromboembolic morbidity among postmenopausal women with early stage breast cancer in a randomized trial of adjuvant tamoxifen
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1398-1406
    • Rutqvist, L.E.1    Mattsson, A.2
  • 36
    • 0025833585 scopus 로고
    • Fatal myocardial infarction in the Scottish adjuvant tamoxifen trial
    • The Scottish Breast Cancer Committee
    • (1991) BMJ , vol.303 , pp. 435-437
    • McDonald, C.C.1    Stewart, H.J.2
  • 40
  • 44
  • 54
    • 0021201213 scopus 로고
    • Antiestrogens 2: Structure-activity studies in a series of 3 aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydrotyphenyl) benzo[b]thiene-3-yl] [4-[2-(1-piperidinyl) ethoxy-phenyl] methanone hydrochloride (LY 156758), a remarkably effective estrogen antagonist with only minimal estrogenicity
    • (1984) J Med Chem , vol.27 , pp. 1057-1066
    • Jones, C.D.1    Jevnikar, M.G.2    Pike, A.J.3
  • 56
    • 0018959791 scopus 로고
    • Uterine bioassay of tamoxifen, trioxifene and a new estrogen antagonist (LY 117018) in rats and mice
    • (1980) Life Sci , vol.26 , pp. 1453-1458
    • Black, L.J.1    Goode, R.L.2
  • 57
    • 0020636027 scopus 로고
    • Inhibition of the uterotropic activity of antiestrogens by the short acting antiestrogen LY 117018
    • (1983) Endocrinolgy , vol.113 , pp. 463-468
    • Jordan, V.C.1    Gosden, B.2
  • 58
    • 0020825481 scopus 로고
    • Differential antiestrogen action on the immature rat uterus: A comparison of hydroxylated antiestrogens with high affinity for the estrogen receptor
    • (1983) J Steroid Biochem , vol.19 , pp. 1249-1258
    • Jordan, V.C.1    Gosden, B.2
  • 59
    • 0344931629 scopus 로고    scopus 로고
    • The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor (ER)
    • (1999) Cancer Res , vol.59 , pp. 4308-4313
    • MacGregor Schafer, J.I.1    Liu, H.2
  • 63
    • 0024509832 scopus 로고
    • Antiestrogen action of toremifene on hormone-dependent, independent and heterogeneous breast tumor growth in the athymic mouse
    • (1989) Cancer Res , vol.49 , pp. 1758-1762
    • Robinson, S.P.1    Jordan, V.C.2
  • 67
    • 0000370865 scopus 로고    scopus 로고
    • Toxicity and early survival results of a prospective, ramdomized adjuvant trial comparing toremifene and tamoxifen in node-positive breast cancer
    • abstr
    • (2000) Proc Am Soc Clin Oncol , vol.334 , pp. 87
    • Holli, K.1
  • 70
  • 71
    • 0025081706 scopus 로고
    • Phase II experience with toremifene in the treatment of ER-positive breast cancer of postmenopausal women
    • (1990) Cancer Invest , vol.8 , pp. 275-276
    • Valavaara, R.1
  • 72
    • 0023913406 scopus 로고
    • Toremifene, a new antiestrogenic compound in the treatment of advanced breast cancer. Phase II study
    • (1990) Eur J Cancer , vol.24 A , pp. 785-790
    • Gunderson, S.1
  • 76
  • 94
    • 0025010197 scopus 로고
    • Metabolism of the 4 iodo derivative of tamoxifen by isolated rat hepatocytes. Demonstration that the iodine atom reduces metabolic conversion and identification of four metabolites
    • (1990) Biochem Pharm , vol.40 , pp. 2277-2283
    • McCague, R.1    Parr, I.B.2    Haynes, B.P.3
  • 96
    • 0003630405 scopus 로고    scopus 로고
    • Discovery and synthesis of [6-hydroxy-3-[4-(1-piperidinyl)-ethoxy-phenoxy]-2-(4-hydroxyphenyl) benzo[b]thiophene: A novel, highly potent selective estrogen receptor modulator (SERM)
    • (1997) J Med Chem , vol.40 , pp. 1407-1416
    • Palkowitz, A.D.1    Glasebrook, A.L.2    Thrasher, J.K.3
  • 100
    • 0030879732 scopus 로고    scopus 로고
    • Characteriztion of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T-47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro
    • (1997) Int J Cancer , vol.73 , pp. 104-112
    • Simard, J.1    Labrie, C.2    Belanger, A.3
  • 101
    • 0031964105 scopus 로고    scopus 로고
    • Comparison of the effects of the antiestrogens EM-800 and tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice
    • (1998) Cancer Res , vol.58 , pp. 60-64
    • Couillard, S.1    Gutman, M.2    Labrie, C.3
  • 102
    • 0031437691 scopus 로고    scopus 로고
    • Inhibitory effect of the novel antiestrogen EM-800 and medroxyprogesterone acetate on estrone-stimulated growth of dimethylbenz[a]an-thracene-induced mammary carcinoma in rats
    • (1997) International J Cancer , vol.3 , pp. 580-586
    • Luo, S.1    Stojanovic, M.2    Labrie, C.3
  • 103
    • 0031765114 scopus 로고    scopus 로고
    • Effect of twenty-four-week treatment with the antiestrogen EM-800 on estrogen-sensitive parameters in intact and ovariectomized mice
    • (1998) Endocrinology , vol.139 , pp. 2645-2656
    • Luo, S.1    Sourla, A.2    Labrie, C.3
  • 112
    • 0028044678 scopus 로고
    • Competitive reverse transcription-polymerase chain reaction analysis indicates that levels of aromatase cytochrome P450 transcripts in adipose tissue of buttocks, thighs and abdomen of women increase with advancing age
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 428-432
    • Bulun, S.E.1    Simpson, E.R.2
  • 113
    • 0027131199 scopus 로고
    • A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
    • erratum 78:494, 1994
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1622-1628
    • Bulun, S.E.1    Price, T.M.2    Aitken, J.3
  • 114
    • 7344242595 scopus 로고    scopus 로고
    • Letrozole, a new oral aromatase inhibitor: Randomized trial comparing 2.5 mg daily, 0.5 mg daily and aminiglutethimide in post-menopausal women with advanced breast cancer
    • Letrozole International Trial Group
    • (1998) Ann Oncol , vol.9 , pp. 639-645
    • Gershanovich, M.1    Chaudri, H.A.2    Campos, D.3
  • 115
    • 0032530988 scopus 로고    scopus 로고
    • Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: Results of a survival update based on a combined analysis of data from two mature phase III trials
    • Arimidex Study Group
    • (1998) Cancer , vol.83 , pp. 1142-1152
    • Buzdar, A.U.1    Jonat, W.2    Howell, A.3
  • 116
    • 0034128928 scopus 로고    scopus 로고
    • Exemestane is superior to megestrol acetate after tamoxifen failure in post-menopausal women with advanced breast cancer: Results of a phase III randomized double-blind trial
    • (2000) J Clin Oncol , vol.18 , pp. 1399-1411
    • Kaufmann, M.1    Bajetta, E.2    Dirix, L.Y.3
  • 117
    • 0031943424 scopus 로고    scopus 로고
    • Letrozole, a new oral aromatase inhibitor for advanced breast cancer: Double-blind randomized trial showing a does effect and improved efficacy and tolerability compared with megestrol acetate
    • (1998) J Clin Oncol , vol.16 , pp. 453-461
    • Dombernowsky, P.1    Smith, I.2    Falkson, G.3
  • 118
    • 0004851436 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer: The coming of age of antiestrogens
    • (1999) Adv Oncol , vol.15 , pp. 3-8
    • Jordan, V.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.