Involvement of nitric oxide in cardioprotective effect of endothelin receptor antagonist during ischemia-reperfusion

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 3 49-3, 2001, Pages

  Gourine, A V ^a   Gonon, A T ^a   Pernow, J ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Reperfusion injury

Indexed keywords

DARUSENTAN; ENDOTHELIN RECEPTOR ANTAGONIST; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SWINE;

EID: 0034976733     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.3.h1105     Document Type: Article

References (39)

1. Cloning and expression of a cDNA encoding an endothelin receptor
2. A receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice
3. Evidence that late preconditioning against myocardial stunning in conscious rabbits is triggered by the generation of nitric oxide
4. Endothelin is released from the porcine aorta: Inhibition by endothelium-derived nitric oxide
5. Interaction of nitric oxide and endothelin-1 in ischemia/reperfusion injury of rat heart
6. Role of endothelin, nitric oxide and L-arginine release in ischaemia/reperfusion injury of rat heart
7. Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled
8. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor
9. Effect of nitrovasodilators and inhibitors of nitric oxide synthase on ischaemic and reperfusion function of rat isolated hearts
10. Early phase acute myocardial infarct size quantification: Validation of the triphenyl tetrazolium chloride tissue enzyme staining technique
11. G-monomethyl-L-arginine in conscious rats
12. The endothelin A receptor antagonist LU 135252 protects the myocardium from neutrophil injury during ischaemia/reperfusion
13. The novel non-peptide selective endothelin A receptor antagonist LU 135,252 protects against myocardial ischaemic and reperfusion injury in the pig
14. The endothelin-1 receptor antagonist BQ-123 reduces infarct size in a canine model of coronary occlusion and reperfusion
15. Activated neutrophil by endothelin-1 caused tissue damage in human umbilical cord
16. Ischemia, reperfusion and the determinants of tissue injury
17. The role of neutrophils in myocardial ischemia-reperfusion injury
18. Plasma nitrate as an index of nitric oxide formation in man: Analyses of kinetics and confounding factors
19. Effects of taprostene on neutrophil-endothelial interactions in isolated coronary arteries
20. Peroxynitrite inhibits leukocyte-endothelial cell interactions and protects against ischemia-reperfusion injury in rats
21. Role of L-arginine in preventing myocardial and endothelial injury following ischaemia/reperfusion in the rat isolated heart
22. Effect of endothelin-1 on neutrophil adhesion to endothelial cells and perfused heart
23. The pathogenesis of cardiovascular disease: Role of the endothelium as a target and mediator
24. The role of endothelin, protein kinase C and free radicals in the mechanism of the postischemic endothelial dysfunction in guinea-pig hearts
25. Nitric oxide: Physiology, pathophysiology, and pharmacology
26. Vascular endothelial cells synthesize nitric oxide from L-arginine
27. The protective effect of L-arginine on myocardial injury and endothelial function following ischaemia and reperfusion in the pig
28. No involvement of endogenous nitric oxide in classical ischemic preconditioning in swine
29. Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
30. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
31. Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats
32. Increased in vivo expression and production of endothelin-1 by porcine cardiomyocytes subjected to ischemia
33. Time course and mechanism of endothelial dysfunction in isolated ischemic- and hypoxic-perfused rat hearts
34. Contribution of endothelin to the coronary vasoconstriction in the isolated rat heart induced by nitric oxide synthase inhibition
35. Local overflow and enhanced tissue content of endothelin following myocardial ischaemia and reperfusion in the pig: Modulation by L-arginine
36. Protective effects of non-peptide endothelin receptor antagonist bosentan on myocardial ischaemic and reperfusion injury in the pig
37. The nonpeptide endothelin receptor antagonist bosentan enhances myocardial recovery and endothelial function during reperfusion of the ischemic rat heart
38. Myocardial release of endothelin (ET) and enhanced ET(A) receptor-mediated coronary vasoconstriction after coronary thrombosis and thrombolysis in pigs
39. Dependence of the metabolism of nitric oxide (NO) in healthy human whole blood on the oxygenation of its red cell haemoglobin