HFE mutations do not account for transfusional iron overload in patients with acute myeloid leukemia

Transfusion

Volumn 41, Issue 6, 2001, Pages 828-831

  Parkkila, Seppo ^a,b   Niemelä, Onni ^a,b   Savolainen, Eeva Riitta ^a,b   Koistinen, Pirjo ^a,b  

^a UNIVERSITY OF OULU   (Finland)

^b SOUTH OSTROBOTHNIA CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FERRITIN; RESTRICTION ENDONUCLEASE; RESTRICTION ENDONUCLEASE BCL 1; RESTRICTION ENDONUCLEASE SNAB 1; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE TRANSFUSION; FEMALE; FERRITIN BLOOD LEVEL; GENE; GENE MUTATION; GENETIC SCREENING; HEMOCHROMATOSIS; HFE GENE; HOMOZYGOSITY; HUMAN; IRON OVERLOAD; IRON STORAGE; MALE; PHLEBOTOMY; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT; RISK FACTOR;

ACUTE DISEASE; ADULT; AGED; BLOOD TRANSFUSION; FEMALE; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; IRON OVERLOAD; LEUKEMIA, MYELOID; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION;

EID: 0034974577     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.2001.41060828.x     Document Type: Article

References (26)

1. Hereditary hemochromatosis. Phenotypic expression of the disease
2. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
3. Mutation analysis in hereditary hemochromatosis
4. Haemochromatosis and HLA-H
5. Haemochromatosis and HLA-H
6. A high prevalence of HLA-H 845A mutations in hemochromatosis patients and the normal population in Eastern England
7. Mutations in the MHC class I-like candidate gene for hemochromatosis in French patients
8. Predominance of the HLA-H Cys282Tyr mutation in Austrian patients with genetic haemochromatosis
9. Correlation between genotype and phenotype in hereditary hemochromatosis: Analysis of 61 cases
10. Ethnic differences in the HFE codon 282 (Cys/Tyr) polymorphism
11. HFE gene knockout produces mouse model of hereditary hemochromatosis
12. The C282Y mutation causing hereditary hemochromatosis does not produce a null allele
13. Genes that modify the hemochromatosis phenotype in mice
14. Transfusion iron overload in adults with acute leukemia: Manifestations and therapy
15. Secondary hemochromatosis as a long-term complication of the treatment of hematologic malignancies
16. Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group
17. Comparison between four and eight cycles of intensive chemotherapy in adult acute myeloid leukemia: A randomized trial of the Finnish Leukemia Group
18. Gelatinase A and B (MMP-2, MMP-9) in leukemia. MMP-2 may indicate a good prognosis in AML
19. Polymorphism in intron 4 of HFE may cause overestimation of C282Y homozygote prevalence in haemochromatosis
20. Cell surface expression of HFE protein in epithelial cells, macrophages, and monocytes
21. Kupffer cell staining by an HFE-specific monoclonal antibody: Implications for hereditary hemochromatosis
22. Transfusion-associated iron overload
23. Molecular medicine and hemochromatosis: At the crossroads
24. Increased risk of acute myocardial infarction in carriers of the hemochromatosis gene Cys282Tyr mutation. A prospective cohort study in men in eastern Finland
25. Linkage disequilibrium mapping in isolated populations: The example of Finland revisited
26. Prevalence of hemochromatosis in Finland