DNA-based vaccination for the treatment of food allergy

Allergy: European Journal of Allergy and Clinical Immunology, Supplement

Volumn 56, Issue 67, 2001, Pages 127-130

  Nguyen, Minh Duc ^a   Cinman, Nadya ^a   Yen, Jack ^a   Horner, Anthony A ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anaphylaxis; CpG motifs; Gene vaccination; Immunostimulatory sequence oligodeoxynucleotides; Immunotherapy

Indexed keywords

ALLERGEN; ALUMINUM POTASSIUM SULFATE; BETA GALACTOSIDASE; DNA VACCINE; FC RECEPTOR; FOOD ALLERGEN; HISTAMINE; IMMUNOGLOBULIN E; OLIGODEOXYNUCLEOTIDE; PERTUSSIS TOXIN;

ALLERGY; ANAPHYLAXIS; ANIMAL MODEL; ANTIBODY RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CROSS LINKING; EXPERIMENTAL MODEL; FOOD ALLERGY; HYPERSENSITIVITY; IMMUNOSTIMULATION; IMMUNOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; SURVIVAL RATE; TH2 CELL; VACCINATION;

ALLERGENS; ANAPHYLAXIS; ANIMALS; DISEASE MODELS, ANIMAL; FOOD HYPERSENSITIVITY; HUMANS; VACCINES, DNA;

EID: 0034973887     PISSN: 01081675     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (19)

1. Food allergy. Part 1: Immunopathogenesis and clinical disorders
2. Fatal and near-fatal anaphylactic reactions to food in children and adolescents
3. DNA-based vaccination reduces the risk of lethal anaphylactic hypersensitivity in mice
4. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization
5. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
6. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants
7. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
8. Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity
9. Anaphylaxis
10. Fatal and near-fatal anaphylactic reactions to food in children and adolescents
11. Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice
12. Passive anaphylaxis in mice with gamma-G antibodies, V. Competitive effects of different immunoglobulins and inhibition of reactions with antiglobulin sera
13. Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gamma RIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis
14. Active anaphylaxis in IgE-deficient mice
15. CpG DNA is a potent enhancer of systemic and mucosal immune responses against hepatitis B surface antigen with intranasal administration to mice
16. Immunostimulatory DNA is a potent mucosal adjuvant
17. Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
18. Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice
19. Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract