Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase

Cellular and Molecular Life Sciences

Volumn 58, Issue 5-6, 2001, Pages 835-843

  Dubus, A ^a   Lloyd, M D ^b   Lee, H J ^b,c   Schofield, C J ^b   Baldwin, J E ^b   Frere J M ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

2 oxoglutarate dependent oxygenase; Cephem antibiotic biosynthesis; Enzyme inactivation; Iron(II); Spectrophotometric assay.

Indexed keywords

6 AMINOPENICILLANIC ACID; ACETYL 6 AMINOPENICILLANIC ACID; ADICILLIN; AMOXICILLIN; AMPICILLIN; CARBENICILLIN; CEFALEXIN; CEPHALOSPORANIC ACID DERIVATIVE; DEACETOXYCEPHALOSPORIN C SYNTHASE; DEACETYLCEPHALOSPORIN C; PENICILLANIC ACID; PENICILLIN DERIVATIVE; PENICILLIN G DERIVATIVE; PENICILLIN V; PHENYLACETYL 7 AMINODEACETOXYCEPHALOSPORANIC ACID; RECOMBINANT ENZYME; SYNTHETASE; TEMOCILLIN; TICARCILLIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG DETERMINATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; NONHUMAN; SPECTROPHOTOMETRY; STREPTOMYCES CLAVULIGERUS;

STREPTOMYCES CLAVULIGERUS;

EID: 0034968454     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000904     Document Type: Article

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