Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus binds to p53 and represses p53-dependent transcription and apoptosis

Journal of Virology

Volumn 75, Issue 13, 2001, Pages 6193-6198

  Seo, T ^a   Park, J ^a   Lee, D ^a   San Gwan Huang, ^a   Choe, J ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON REGULATORY FACTOR 1; PROTEIN P53;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL FUNCTION; DNA BINDING; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; KAPOSI SARCOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; VIRUS TRANSCRIPTION;

APOPTOSIS; BINDING SITES; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; INTERFERON REGULATORY FACTORS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; VIRAL PROTEINS;

EID: 0034968101     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.13.6193-6198.2001     Document Type: Article

References (26)

1. Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300
2. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
3. p53 inhibition by the LANA protein of KSHV protects against cell death
4. KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway
5. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias
6. Characteristics of a human cell line transformed by DNA from human adenovirus type 5
7. p53 mutations in human cancers
8. Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease
9. Oligomerization of oncoprotein p53
10. cAMP response element-binding protein-binding protein binds to human papillomavirus E2 protein and activates E2-dependent transcription
11. p53, the cellular gatekeeper for growth and division
12. Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor
13. Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor
14. Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells
15. Twenty years of p53 research: Structural and functional aspects of the p53 protein
16. The K-bZIP protein from Kaposi's sarcoma-associated herpesvirus interacts with p53 and represses its transcriptional activity
17. Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected disease: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease
18. The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300
19. Sequence-specific transcriptional activation is essential for growth suppression by p53
20. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture
21. Kaposi's sarcoma-associated herpesvirus LANA2 is a B-cell-specific latent viral protein that inhibits p53
22. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)
23. Transcription mapping of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genome in a body cavity-based lymphoma cell line (BC-1)
24. Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) binds to and inhibits transactivation of CREB-binding protein
25. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease
26. Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription